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| Cas No.: | 22161-81-5 |
| Chemical Name: | (S)-(+)-ketoprofen |
| Synonyms: | (S)-(+)-ketoprofen;S-(+)-Ketoprofen;(S)-ketoprofen;Dexketoprofen;(D)-KETOPROFEN;(S)-2-(3-Benzoylphenyl)propanoic acid;(2S)-2-(3-benzoylphenyl)propanoic acid;Keral;S-ketoprofen;(S)-(+)-2-(3-Benzoylphenyl)propionic acid |
| SMILES: | O=C(O)[C@@H](C)C1=CC=CC(C(C2=CC=CC=C2)=O)=C1 |
| Formula: | C16H14O3 |
| M.Wt: | 254.280564785004 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | S-(+)-Ketoprofen is a potent inhibitor of both COX-1 and COX-2 with IC50s of 1.9 and 27 nM, respectively. |
| Target: | COX-1:13 μM (IC50) COX-2:370 μM (IC50) |
| In Vitro: | S-(+)-Ketoprofen (Compound 1) is a potent inhibitor of both COX-1 and COX-2 with IC50s of 1.9 and 27 nM, respectively[1]. |
| References: | [1]. Palomer A, et al. Modeling cyclooxygenase inhibition. Implication of active site hydration on the selectivity ofketoprofen analogues. J Med Chem. 2000 Jun 1;43(11):2280-4. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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| 2018-0101 |
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