TRPA1 agonist-3|CAS 3033961-38-2|DC Chemicals

Cas No.:	3033961-38-2
Chemical Name:	TRPA1 agonist-3
Synonyms:	BEN28010;BEN 28010
Formula:	C₂₀H₂₂N₈
M.Wt:	374.44
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC74584	LY2880070	LY2880070 is an orally active inhibitor of CHK1. LY2880070 can be used as an anticancer agent and shows promise in preclinical models of pancreatic ductal adenocarcinoma (PDAC) when used in combination with DNA-damaging agents.
DC8259	PF0477736	PF 477736 is a CHK inhitor with Ki values of 0.49 and 47 nM for Chk1 and Chk2 respectively. A proprietary compound targeting cell cycle checkpoint kinase 1 (chk1) with potential chemopotentiation activity
DC81676	TRPA1 agonist-3	TRPA1 agonist-3 is a selective and orally active TRPA1 agonist, with EC50 values of 50.05 μM and 314.04 μM for human and mouse TRPA1, respectively. TRPA1 agonist-3 does not activate hTRPV1, mTRPV2, hTRPV3, hTRPV4, hTRPC6, or hTRPM8 channels. TRPA1 agonist-3 alleviates inflammatory pain in mice through a channel desensitization mechanism.
DC81635	Thalidomide-5-NH-C9-acid	Thalidomide-5-NH-C9-acid is a synthetic E3 ligase ligand-linker conjugate containing a Thalidomide-based Cereblon ligand and one linker.
DC80292	Barringtogenol C	Barringtogenol C (Theasapogenol B) is one of seeds sapogenols of Thea sinensis L. Barringtogenol C is a type of barrigenol triterpenoid. Barringtogenol C derivatives exhibits antitumor activity.
DC78719	MCL1020	MCL1020 is a CHK1 inhibitor with an IC50 of 1.61 μM. MCL1020 properly occupies the ATP pocket by interacting with a diverse range of the sites of CHK1 kinase. MCL1020 can be used for the study of hematologic malignancies.
DC48120	Chk1-IN-6	Chk1-IN-6 is a potent, selective, and orally bioavailable CHK1 inhibitor candidate.