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BP-198

  Cat. No.:  DC76103  
Chemical Structure
For research use only. We do not sell to patients.
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More than 5000 active chemicals with high quality for research!
Field of application
BP-198 is an Mpro PROTAC degrader. BP-198 promotes the ubiquitination and degradation of Mpro. BP-198 has antiviral effects against SARS-CoV-2 (IC50: 11.8 μM) and has stronger activity against drug-resistant viruses.
Cas No.:
Chemical Name: BP-198
SMILES: C[C@@H](C(N[C@@H](C1CCCCC1)C(N2CCC[C@H]2C3=NC(C(C4=CC(OCCCN5N=NC(CSC(C)([C@H](NC(C(F)(F)F)=O)C(N6[C@H](C(N[C@H](C#N)C[C@@H]7CCNC7=O)=O)[C@]8([H])[C@](C8(C)C)([H])C6)=O)C)=C5)=CC=C4)=O)=CS3)=O)=O)NC.OC(C(F)(F)F)=O
Formula: C56H72F6N12O10S2
M.Wt: 1251.37
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
Cat. No. Product name Field of application
DC40958 A2ti-2 A2ti-2 is a selective and low-affinity annexin A2/S100A10 heterotetramer (A2t) inhibitor with an IC50 of 230 μM. A2ti-2 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. A2ti-2 prevents human papillomavirus type 16 (HPV16) infection.
DC40957 A2ti-1 A2ti-1 is a selective and high-affinity annexin A2/S100A10 heterotetramer (A2t) inhibitor with an IC50 of 24 μM. A2ti-1 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. A2ti-1 prevents human papillomavirus type 16 (HPV16) infection.
DC76105 Secutrelvir Secutrelvir is the inhibitor for 3CL protease that exhibits antiviral activity through inhibition of SARS-CoV-2 replication.
DC76104 Dihydro K22 Dihydro K22 is a derivative of the antiviral agent K22. Pyridoxine tri(2-hexyldecanoate) is a cosmetic ingredient.
DC76103 BP-198 BP-198 is an Mpro PROTAC degrader. BP-198 promotes the ubiquitination and degradation of Mpro. BP-198 has antiviral effects against SARS-CoV-2 (IC50: 11.8 μM) and has stronger activity against drug-resistant viruses.
DC76102 AS-0017445 AS-0017445 is an inhibitor targeting the main protease of both the current coronavirus and the virus that caused the Middle East Respiratory Syndrome (MERS) outbreak. AS-0017445 inhibits the viral protein processing in host cells and thus prevents viral replication.
DC72841 5-Bromo-2′-deoxy-2′-fluorouridine 5-Bromo-2′-deoxy-2′-fluorouridine (Example 1), a 5-halo analog, is potential as an antiviral agent.
DC72299 LabMol-301 LabMol-301 inhibits both NS5 RdRp and NS2B-NS3pro activity (IC50: 0.8 and 7.4 μM, respectively). LabMol-301 has a cytoprotective effect and prevents Zika virus (ZIKV)-induced cell death.
DC72298 NITD-688 NITD-688 is an orally active pan-serotype inhibitor of the dengue virus NS4B protein. NITD-688 can be used in the research of dengue virus (DENV).
DC71199 Hydroxyethylamine Hydroxyethylamine (Compd VII) is a SARS-CoV-2 3CLpro inhibitor with an IC50 of ~10 μM in the spread assay. Hydroxyethylamine has potent antiviral activities.
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