CDK8-IN-2|CAS 150438-02-1|DC Chemicals

Cas No.:	150438-02-1
Chemical Name:	CDK8-IN-2
Formula:	C₂₇H₂₂F₃N₇O₃
M.Wt:	549.5
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC7224	PD 123319	PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM.
DC4210	Azilsartan kamedoxomil	Azilsartan medoxomil is an angiotensin II receptor antagonist indicated for the treatment of mild to moderate essential hypertension.
DC80497	CXCR6 antagonist 1	CXCR6 antagonist 1 (Compound 81) is an orally active CXCR6 antagonist. CXCR6 antagonist 1 inhibits the CXCR6 receptor signaling pathway, including β-arrestin recruitment and Forskolin-induced cAMP production. CXCR6 antagonist 1 reduces tumor growth in a mouse xenograft model of hepatocellular carcinoma. CXCR6 antagonist 1 can be used in research related to hepatocellular carcinoma.
DC80405	CDK8-IN-2	CDK8-IN-2 is an orally active CDK8 inhibitor of an IC50 values of 0.010 μM. CDK8-IN-2 shows a CDK19 IC50 value of 0.026 μM. CDK8-IN-2 inhibits phospho-STAT1, a pharmacodynamic biomarker of CDK8. CDK8-IN-2 inhibits WNT pathway activity. CDK8-IN-2 can be used for the research of colorectal carcinoma.
DC80374	Cathepsin C-IN-7	Cathepsin C-IN-7 (Page 68) is a Cathepsin C inhibitor. Cathepsin C-IN-7 can be used in research related to primary cancers and cancer metastases.
DC79735	PD 121981	PD 121981 is a angiotensin II receptor antagonist. PD 121981 can be used for the research of cardiovascular disease.
DC79479	L-163017	L-163017 is a potent, orally active and nonpeptide angiotensin II receptor (AT) antagonist. L-163017 can inhibit prevent the pressor response to angiotensin II and reduce blood pressure. L-163017 can be used for the research of cardiovascular disease, such as hypertension.
DC79449	L-163007	L-163007 is an orally active AT1/2 receptor antagonist. L-163007 can be used for the research of cardiovascular disease, such as hypertension.
DC79427	GA-0056	GA-0056 is an angiotensin II receptor blocker. GA-0056 can be used in the research of heart disease.
DC79108	L-161638	L-161638 is a potent, selective and orally active AT2 receptor antagonist. L-161638 can be used for the research of cardiovascular disease, such as hypertension.