CVN766|CAS 1803557-42-7|DC Chemicals

Cas No.:	1803557-42-7
Chemical Name:	CVN766
SMILES:	CCC1=NC(C(F)(F)F)=CN=C1N[C@@H]2[C@@H](NC(C3=NC=CC=C3N4N=CC=N4)=O)CCC2
Formula:	C₂₀H₂₁F₃N₈O
M.Wt:	446.44
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

Cat. No.	Product name	Field of application
DC73482	CVN766	CVN766 (CVN 766) is a potent, exquisitely selective orexin 1 receptor (OX1R) antagonist with IC50 of 8 nM, 1000-fold selective over OX2R.
DC73480	(R)-YNT-3708	(R)-YNT-3708 is a potent, selective orexin 1 receptor (OX1R) agonist with EC50 of 7.48 nM and Emax 101%, 22-fold selectivity over OX2R (IC50=168 nM).
DC71983	Nivasorexant	Nivasorexant is a potent orexin receptor antagonist.
DC28246	EMPA	EMPA is a high-affinity, reversible and selective orexin OX2 receptor antagonist. [3H]EMPA binds to human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM respectively.
DC9573	SB-674042	SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM); exhibits 100-fold selectivity for OX1 over OX2 receptors.
DC7277	SB-408124	SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively; exhibits 50-fold selectivity over OX2 receptor.
DC8419	SB-334867	SB-334867 is a selective orexin-1 (OX1) receptor antagonist.
DC7495	SB-334867 HCl	SB-334867 is a selective non-peptide orexin OX1 receptor antagonist with a pKb value of 7.2.
DC11439	Nemorexant	ACT-541468 is a dual orexin receptor antagonist.