MK-0489|CAS 378242-00-3|DC Chemicals

Cas No.:	378242-00-3
Chemical Name:	MK-0489
Formula:	C₁₆H₁₄O₄S
M.Wt:	302.34
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC71542	2-MPPA	2-MPPA (GPI-5693) is an orally active and selective glutamate carboxypeptidase II (GCP II; PSMA) inhibitor with an IC50 of 90 nM.
DC47713	GCPII-IN-1 TFA	GCPII-IN-1 TFA is a glutamate carboxypeptidase II (GCPII, or PSMA) inhibitor scaffold with a Ki of 44.3 nM.
DC81054	MK-0489	MK-0489 is an orally active, highly effective, and selective MC4R agonist. MK-0489 exhibits a strong binding affinity (IC50 = 13 nM) and functional agonist activity (EC50 = 4.6 nM) at human MC4R. MK-0489 shows functional activity of 22 nM (EC50) on mouse MC4R and 1.7 μM (EC50) on mouse MC3R. MK-0489 can be used for the study of obesity.
DC78070	PrCP-7414	PrCP-7414 is a prolylcarboxypeptidase (PRCP) inhibitor. PrCP-7414 can block the receptor tyrosine kinase (RTK) signaling pathway mediated by PRCP and the GPCR-RTK crosstalk. PrCP-7414 can inhibit cancer cells proliferation and induce apoptosis. PrCP-7414 can be used for the research of cancer, such as triple negative breast cancer (TNBC).