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GPS491

  Cat. No.:  DC47604   Featured
Chemical Structure
2655502-29-5
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More than 5000 active chemicals with high quality for research!
Field of application
GPS491 (EC50 = 0.47 μM) suppresses expression of the HIV-1 structural protein Gag and alters HIV-1 RNA accumulation, decreasing the abundance of RNAs encoding the structural proteins while increasing levels of viral RNAs encoding the regulatory proteins.
Chemicals PropertiesBiological activity COAMSDSRelated productsDatasheet
Cas No.: 2655502-29-5
Chemical Name: GPS491
Synonyms: GPS491
SMILES: N(C1=NC2=CC=C(C(F)(F)F)C=C2S1)C(C1=CN=C(C(F)(F)F)S1)=O
Formula: C13H5F6N3Os2
M.Wt: 397.318720579147
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: GPS491 (EC50 = 0.47 μM) suppresses expression of the HIV-1 structural protein Gag and alters HIV-1 RNA accumulation, decreasing the abundance of RNAs encoding the structural proteins while increasing levels of viral RNAs encoding the regulatory proteins.
References: [1]. Zamiri M, et al. 2-Trifluoromethylthiazole-5-carboxamides: Analogues of a Stilbene-Based Anti-HIV Agent that Impact HIV mRNA Processing. ACS Med Chem Lett. 2021 Oct 29;12(11):1818-1823.
COA
MSDS
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