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IY7640

  Cat. No.:  DC70518  
Chemical Structure
1402881-96-2
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More than 5000 active chemicals with high quality for research!
Field of application
IY7640 (IY-7640) is a small molecule targeting the stalk region of the influenza HA protein, blocks HA-mediated membrane fusion of H1N1, H3N2, and influenza B viruses in cells.IY7640 demonstrated potency against H1N1, H3N2, H5N1, H7N9, and H9N2 subtypes of IAV, including the 2009 pandemic H1N1 (pH1N1) virus (A/Korea/01/2009, rK09), with EC50 of 0.62-220 uM in plaque reduction assay in MDCK cells.IY7640 successfully inhibited rK09 replication in cells at a level comparable to that of oseltamivir, K09 HA fusion was inhibited only by 1 uM IY7640.The stalk region of the influenza HA protein is highly conserved across different (sub)types of influenza viruses.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1402881-96-2
Chemical Name: IY7640
Synonyms: IY-7640
Formula: C23H22F3N3O3
M.Wt: 445.442
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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