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JMN3-003

  Cat. No.:  DC70522  
Chemical Structure
1331868-55-3
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More than 5000 active chemicals with high quality for research!
Field of application
JMN3-003 is a host-directed inhibitor with potent antiviral activity against a panel of myxovirus family members with EC50 of 10-70 nM.JMN3-003 shows activity against MeV at 170 (viral CPE-reduction assay) and 30 nM (virus yield reduction assay) and does not display any detectable acute cytotoxicity.JMN3-003 also shows superb antiviral activity against a selection of clinical-relevant paramyxovirus (RSV, MuV, and HPIV3) and orthomyxovirus (influenza) family members.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1331868-55-3
Chemical Name: JMN3-003
Formula: C24H22ClN3O2S
M.Wt: 451.969
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC70936 ZHAWOC9045 ZHAWOC9045 (F2205-0189) is a potent, host-specific small-molecule inhibitor of paramyxovirus (Canine distemper virus, CDV IC50=0.7 uM) and pneumovirus (RSV, IC50=5.9 uM) replication.ZHAWOC9045 displays broad-spectrum antiviral activity, inhibits CDV in a host cell-dependent manner.
DC70935 ZHAWOC21026 ZHAWOC21026 is a highly potent, host-specific small-molecule inhibitor of paramyxovirus (Canine distemper virus, CDV IC50=3.2 nM) and pneumovirus (RSV, IC50=31 nM) replication.
DC21382 EIDD-1931(NHC) EIDD-1931 (β-d-N4-Hydroxycytidine, NHC) inhibits both murine hepatitis virus (MHV) (EC50 of 0.17 μM) and Middle East respiratory syndrome CoV (MERS-CoV) (EC50 of 0.56 μM) with minimal cytotoxicity. It also inhibits SARS-CoV-2 and multiple 2 endemic, epide
DC11647 JNJ-2408068 JNJ 2408068 is a potent RSV (respiratory syncytial virus) inhibitor. JNJ2408068 significantly inhibits replication of RSV A and B subtypes in the lungs of cotton rats without any evidence of toxicity. The minimum protective dose of JNJ 2408068 appears to be approximately 0.39 mg/kg[1].
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DC73031 JNJ-8003 JNJ-8003 is a highly potent, selective, non-nucleoside inhibitor of respiratory syncytial virus (RSV) polymerase with IC50 of 0.67 nM, shows EC50 of 0.15 nM in RSV subgenomic replicon assays.
DC73030 AVG-388 AVG-388 is a potent, allosteric, orally efficacious inhibitor of respiratory syncytial virus (RSV) RNA synthesis, potently blocks RSV RNA-dependent RNA polymerase (RdRP) bioactivity, exhibits strong antiviral efficacy in vivo.
DC72853 BMS-433771 dihydrochloride hydrate BMS-433771 dihydrochloride hydrate is a potent orally active inhibitor of respiratory syncytial virus (RSV). BMS-433771 dihydrochloride hydrate is active against both A and B groups of RSV, with an average EC50 of 20 nM. BMS-433771 dihydrochloride hydrate can be used for the research of respiratory tract disease.
DC70522 JMN3-003 JMN3-003 is a host-directed inhibitor with potent antiviral activity against a panel of myxovirus family members with EC50 of 10-70 nM.JMN3-003 shows activity against MeV at 170 (viral CPE-reduction assay) and 30 nM (virus yield reduction assay) and does not display any detectable acute cytotoxicity.JMN3-003 also shows superb antiviral activity against a selection of clinical-relevant paramyxovirus (RSV, MuV, and HPIV3) and orthomyxovirus (influenza) family members.
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