L 691816|CAS 150461-07-7|DC Chemicals

Cas No.:	150461-07-7
Chemical Name:	L 691816
SMILES:	CC(C)(CC1=NN=NN1)CC2=C3C4=C(C=CC(OCC5=NC=C(C=C5)C6=CC=CC=C6)=C4CC(S3)C)N2CC7=CC=C(C=C7)Cl
Formula:	C₃₆H₃₅ClN₆Os
M.Wt:	635.22
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

Cat. No.	Product name	Field of application
DC46158	CAY10698	CAY10698 (compound 1) is a potent and selective inhibitor of 12-Lipoxygenase (12-LOX) with an IC50 of 5.1 μM. CAY10698 is inactive against 5-LOX, 15-LOX-1, 15-LOX-2 and COX-1/2.
DC44939	CDC 5-LO inhibitor	Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC) is a potent and direct inhibitor of 5-LO (5-Lipoxygenase) that reduces 5-LO activity in cell-free assays. CDC also inhibits 12-LO and 15-LO.
DC76861	WY-50295	WY-50295 is an orally active and selective 5-lipoxygenase inhibitor. WY-5029 inhibits LTB4 formation in rat whole blood leukocytes (IC50: 40 μM and oral ED50: 18 mg/kg). WY-50295 can be used in the study of asthma and other leukotriene-dependent diseases.
DC76860	NCTT-956	NCTT-956 is a very effective platelet 12-lipoxygenase (12-LOX) activity-specific inhibitor.
DC76859	BLX-3887	BLX-3887 is a selective 15-lipoxygenase type 1 (15-LO-1) inhibitor with an IC50 of 32 nM. BLX-3887 can be utilized in research related to the 15-LO pathways.
DC76858	15(S)-HEDE	15(S)-HEDE (Compound 8) is an analogue of 15-HEDE-induced acute liver injury and non-alcoholic steatohepatitis (NASH) in mouse models.
DC72894	L 691816	L 691816 is a potent, selective and orally active inhibitors of 5-lipoxygenase. L 691816 can be used for the research of allergies and asthma.
DC72375	2-TEDC	2-TEDC is a potent inhibitor of 5-, 12-, and 15-lipoxygenase with IC50 values of 0.09 μM, 0.013 μM and 0.5 μM, respectively. 2-TEDC can be used for the research of atheroscrelosi.
DC71810	Masoprocol	Masoprocol (meso-Nordihydroguaiaretic acid) is a potent and orally active lipoxygenase inhibitor. Masoprocol shows antihyperglycemic activity. Masoprocol decreases the glucose concentration and hepatic triglyceride in vivo. Masoprocol has the potential for the research of type II diabetes.
DC71055	HZ52	HZ52 is a potent, reversible 5-lipoxygenase inhibitor, blocking leukotriene synthesis with an IC50 of 0.7 μM in intact human polymorphonuclear leukocytes.