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L2H2-6OTD

  Cat. No.:  DC72320  
Chemical Structure
1016263-75-4
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Field of application
L2H2-6OTD, containing one to four G-quadruplex binding loops, is a telomeric inhibitor analogue. l2H2-6OTD has telomerase inhibitory activity with an IC50 value of 15 nM.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1016263-75-4
Chemical Name: L2H2-6OTD
SMILES: NCCCC[C@H](NC(C1=COC(C2=COC3=N2)=N1)=O)C4=NC(C5=NC(C6=NC(C(N[C@H](C7=NC3=CO7)CCCCN)=O)=CO6)=CO5)=CO4
Formula: C30H30N10O8
M.Wt: 658.62
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_36771_DC72320_1016263-75-4
COA
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Cat. No. Product name Field of application
DC29105 Epithalon Epitalon is an anti-aging agent and a telomerase activator. Epitalon has an inhibitory effect of the on the development of spontaneous tumors in mice, has geroprotective actions and intranasal administration increases neuronal activity. Epitalon can be used for cancer, old age and Retinitis Pigmentosa.
DC8861 2'-Deoxythioguanosine 6-thio-dG is a nucleoside analog and telomerase substrate.
DC11310 MST312 MST312 is a telomerase inhibitor (IC50 = 0.67 μM in a TRAP assay).
DC7085 BIBR-1532 BIBR 1532 is a potent, selective, non-competitive telomerase inhibitor with IC50 of 100 nM.
DC73228 Teloxantron Teloxantron (Telomerase inhibitor TXT4) is a potent small molecule inhibitor of telomerase activity with IC50 of 9.61 uM, 7-fold lower than BIBR1532 (Cat# PC-45170), inhibits the processivity of telomerase with preferential DNA damage on telomeres.
DC73227 DIZ-3 DIZ-3 is a dimeric aryl-substituted imidazole as a selective multimeric G-quadruplex (G4) ligand, intercalates into the G4-G4 interface, induces cell cycle arrest and apoptosis, and inhibits cell proliferation in alternative lengthening of telomere (ALT)
DC72320 L2H2-6OTD L2H2-6OTD, containing one to four G-quadruplex binding loops, is a telomeric inhibitor analogue. l2H2-6OTD has telomerase inhibitory activity with an IC50 value of 15 nM.
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