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TPP-1

  Cat. No.:  DC44155  
Chemical Structure
2426685-25-6
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More than 5000 active chemicals with high quality for research!
Field of application
TPP-1 is a potent inhibitor of the PD-1/PD-L1 interaction. TPP-1 binds specifically to PD-L1 with a high affinity (KD=95 nM). TPP-1 inhibits human tumor growth in vivo via reactivating T-cell function.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2426685-25-6
Chemical Name: TPP-1
Synonyms: SGQYASYHCWCWRDPGRSGGSK
Formula: C107H150N34O32S2
M.Wt: 2488.67
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC46565 PD-1-IN-20 PD-1-IN-20 is the less active enantiomer of PD-1-IN-1. PD-1-IN-1 is an inhibitor of programmed cell dealth-1 (PD-1) extracted from patent WO 2015033299 A1, compound example 4.
DC46218 PD-1-IN-17 TFA PD-1-IN-17 TFA is a programmed cell death-1 (PD-1) inhibitor extracted from patent WO2015033301A1, Compound 12, inhibits 92% splenocyte proliferation at 100 nM.
DC44156 TPP-1 TFA TPP-1 TFA is a potent inhibitor of the PD-1/PD-L1 interaction. TPP-1 TFA binds specifically to PD-L1 with a high affinity (KD=95 nM). TPP-1 TFA inhibits human tumor growth in vivo via reactivating T-cell function.
DC44155 TPP-1 TPP-1 is a potent inhibitor of the PD-1/PD-L1 interaction. TPP-1 binds specifically to PD-L1 with a high affinity (KD=95 nM). TPP-1 inhibits human tumor growth in vivo via reactivating T-cell function.
DC42066 Human PD-L1 inhibitor III Human PD-L1 inhibitor III is a human PD-L1 inhibitor.
DC41989 Human PD-L1 inhibitor V Human PD-L1 inhibitor V, a polypeptide, is a competitive human PD-1 protein inhibitor with a Kd value of 3.32 μM. Human PD-L1 inhibitor V inhibit the interaction of hPD-1/hPD-L1.
DC41988 Human PD-L1 inhibitor IV Human PD-L1 inhibitor IV, a polypeptide, is a competitive human PD-1 protein inhibitor with a Kd value of 1.38 μM. Human PD-L1 inhibitor IV inhibits the interaction of hPD-1/hPD-L1.
DC41982 Human PD-L1 inhibitor II Human PD-L1 inhibitor II is a potent PD-L1 inhibitor with anti-cancer activity.
DC28554 PD-1/PD-L1-IN 5 PD-1/PD-L1-IN 5 is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Example 1, has an IC50 of ≤100 nM.
DC28140 PD-1/PD-L1-IN 3 TFA PD-1/PD-L1-IN 3 TFA is a PD-1/PD-L1 interaction inhibitor extracted from patent WO2014151634A1, compound 1. PD-1/PD-L1-IN 3 TFA inhibits the binding of human PD-1 to PD-Ll with an IC50 of 9 nM.
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