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Zevaquenabant

  Cat. No.:  DC70932  
Chemical Structure
1998760-00-1
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More than 5000 active chemicals with high quality for research!
Field of application
Zevaquenabant ((S)-MRI-1867) is a peripherally restricted, orally bioavailable dual CB1 receptor/iNOS inhibitor.Zevaquenabant ((S)-MRI-1867) (3 mg/kg, p.o.) ameliorated obesity-induced kidney morphological and functional changes via decreasing kidney inflammation, fibrosis, oxidative stress, and renal injury.The hybrid CB1R/iNOS inhibitor Zevaquenabant ((S)-MRI-1867) has greater antifibrotic efficacy than inhibition of CB1R alone.(S)-MRI-1867 reduced hepatic steatosis and the rate of hepatic VLDL secretion, upregulated hepatic LDLR expression, and reduced the circulating levels of proprotein convertase subtilisin/kexin type 9 (PCSK9) in diet-induced obesity (DIO mice).
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1998760-00-1
Chemical Name: Zevaquenabant
Synonyms: (S)-MRI-1867
Formula: C25H21ClF3N5O2S
M.Wt: 547.981
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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