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Antibiotics and Antivirals

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Cat. No. Product Name Field of Application Chemical Structure
DC45450 Haplopine
Haplopine possesses photo-activated antimicrobial and DNA binding activities.
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DC45443 Epimagnolin A
Epimagnolin A, a furfuran lignan, shows mild antiplasmodial activities (IC50=5.7 μg/mL) without noticeable toxicity on mammalian normal cells.
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DC45435 3′,4′,5′,5,6,7-Hexamethoxyflavone
3′,4′,5′,5,6,7-Hexamethoxyflavone is a flavonoid with antiprotozoal activity. 3′,4′,5′,5,6,7-Hexamethoxyflavone inhibits trypanosoma bruceirhodesiense with IC50 of 21.3 μM (8.58 g/mL).
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DC45431 3-Oxobetulin
3-Oxobetulin, an antifungal agent, shows antifungal activities against white rot fungus L. betulina and the brown rot fungus L. sulphureus.
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DC45423 3β,7β,15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone
3β,7β,15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone is a natural compound that could be isolated from G. lucidum with antimycobacterial activity.
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DC45422 Cheilanthifoline
Cheilanthifoline, an alkaloid, is isolated from Corydalis calliantha. Cheilanthifoline exhibits antiplasmodial activities against Plasmodium falciparum, with IC50s of 0.90 μg/mL and 1.22 μg/mL for wild type (TM4) and multidrug resistant (K1) strains, respectively.
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DC45412 (-)-Corypalmine
(-)-Corypalmine (Discretinine), an alkaloid that could be isolated from the stem of Guatteriopsis friesiana, possesses antimicrobial activity.
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DC45408 Nudicaucin B
Nudicaucin B is a triterpenoid saponi found in Hedyotis nudicaulis. Nudicaucin B has antifungal activities.
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DC45405 Chamaechromone
Chamaechromone is a biflavonoid ingredient isolated from the roots of Stellera chamaejasme L. (Thymelaeaceae). Chamaechromone possesses anti-hepatitis B virus (HBV) effects against the surface antigen of HBV (HBsAg) secretion and has insecticidal activities.
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DC45397 4aα,7α,7aα-Nepetalactone
4aα,7α,7aα-Nepetalactone exhibits antibacterial activity, and inhibits Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella typhi and Enterococcus faecalis.
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DC45369 Octaethylene glycol monododecyl ether
Octaethylene glycol monododecyl ether (C12E8) is an non-ionic detergent that can be used for membrane protein extraction. Octaethylene glycol monododecyl ether can solubilize the viral membrane of intact influenza virus.
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DC45367 Latrunculin B
Latrunculin B, an antimicrobial marine alkaloid, is an actin polymerization inhibitor. Latrunculin B regulates pulmonary vein electrophysiological characteristics and attenuates stretch-induced arrhythmogenesis. Antifungal and antiprotozoal activity.
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DC45366 Bruceine B
Bruceine B inhibits protein synthesis and nucleic acid synthesis.
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DC45344 Multicaulisin
Multicaulisin, a new Diels-Alder type adduct from Morus multicaulis roots, potently effects against Staphylococcus aureus (MRSA) isolates. Multicaulisin is an antibacterial drug and has the potential for MRSA infections research.
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DC45191 6-O-Methacrylate
6-O-Methacrylate, a trilobolide, is isolated from the leaves of Wedelia trilobata. 6-O-Methacrylate displays marked antimalarial activity, with IC50 of 8.9 μg/mL against P. falciparum parasite. 6-O-Methacrylate also has anti-tobacco mosaic virus (TMV) activity.
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DC45190 Antitrypanosomal agent 2
Antitrypanosomal agent 2 is a potent and selective trypanosoma brucei inhibitor.
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DC45188 trans-4-Methylcyclohexanamine
trans-4-Methylcyclohexanamine is an intermediate and can be used for the development of T. cruzi enzyme inhibitor.
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DC44937 2′-Deoxy-2′-fluoroguanosine
2′-Deoxy-2′-fluoroguanosine, a nucleoside analog, is a potent inhibitor of influenza virus strains, with an EC90 of <0.35 μM for influenza virus A and B strains. 2′-Deoxy-2′-fluoroguanosine significantly inhibits replication of influenza virus in the upper respiratory tract, resulting in amelioration of fever and nasal inflammation.
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DC44936 Oseltamivir-acetate
Oseltamivir-acetate is an impurity of Oseltamivir. Oseltamivir is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B.
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DC44935 2'-Deoxy-2'-fluorouridine
2'-Deoxy-2'-fluorouridine can be used as an intermediate for antiinfluenza virus agents synthesis.
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DC44934 M2e, human
M2e, human, consisting of the 23 extracellular residues of M2 (the third integral membrane protein of influenza A), has been remarkably conserved in all human influenza A, which is a valid and versatile vaccine candidate to protect against any strain of human influenza A.
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DC44928 2-Hydroxyacetophenone
2-Hydroxyacetophenone is a principal root volatile of the Carissa edulis. 2-Hydroxyacetophenone shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 1.8 mM.
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DC44927 Schisantherin D
Schisantherin D is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera. Schisantherin D shows anti-HIV replication activities with an EC50 of 0.5 μg/mL. Schisantherin D inhibits endothelin receptor B (ETBR) and has hepatoprotective effects.
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DC44926 2-Hydroxycinnamic acid
2-Hydroxycinnamic acid is isolated from the methanol extract of Cinnamomum cassia. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 1.8 mM
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DC44925 Peritassine A
Peritassine A, an alkaloid that could be isolated from Tripterygium wilfordii Hook. f., possesses anti-HIV activity.
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DC44924 PKF050-638
PKF050-638 is a potent and selective inhibitor of HIV-1 Rev (IC50=0.04 μM). PKF050-638 inhibits the CRM1-mediated Rev nuclear export by disrupting CRM1-NES interaction.
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DC44923 Cys-TAT(47-57)
Cys-TAT(47-57) (Cys-[HIV-Tat (47-57)]) is an arginine rich cell penetrating peptide derived from the HIV-1 transactivating protein.
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DC44917 2'-O-Methylcytidine
2'-O-Methylcytidine is a 2'-substituted nucleoside as a inhibitor of HCV replication. 2'-O-Methylcytidine inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.
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DC44909 6-Chloro-7-deazapurine-β-D-riboside
Chloro-7-deazapurine-β-D-riboside is a nucleoside derivative and has antifungal activity.
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DC44908 2'-Deoxy-5'-O-DMT-2'-fluorouridine
2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5’-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity.
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