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Home > Inhibitors & Agonists > Metabolic Enzyme/Protease > Endogenous Metabolite

Endogenous Metabolite

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Cat. No. Product Name Field of Application Chemical Structure
DC76943 D-Galacturonic acid
D-Galacturonic acid (D-galUA), as the main component of pectin, is abundantly present in plants. The carboxyl group of D-Galacturonic acid can bind to metal cations. D-Galacturonic acid plays an important role in the food industry, pharmaceutical field, and heavy metal removal, among other aspects.
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DC76942 Deacetylforskolin
Deacetylforskolin is a deacetylated derivative of forskolin that can be extracted from C. forskohlii. Deacetylforskolin activates rat adipocyte adenylyl cyclase (IC50 = 20 µM), inhibits glucose transport in rat adipocyte plasma membranes and exhibits antihypertensive activity.
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DC76941 D-Biopterin
D-Biopterin is an enantiomer of L-Biopterin.
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DC76940 D3017
D3017 is the main metabolite of D2624, which has oral bioactivity and anti-convulsant effects. D3017 ED50 value is 1.5 mg/kg in mice, and it can be used for research on severe generalized tonic-clonic seizures (grand mal) and complex partial epilepsy.
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DC76939 Corynecin IV
Corynecin IV is a chloramphenicol-like bacterial metabolite originally isolated from Corynebacterium.
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DC76938 Conglobatin C1
Conglobatin C1 is a bacterial metabolite and has anticancer activity. Conglobatin C1 is cytotoxic to NS-1 mouse myeloma cells (IC50 = 1.05 μg/mL) .
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DC76937 Cholylglycylamidofluorescein
Cholylglycylamidofluorescein (CGamF) is a fluorescent probe for hepatic bile acid transport. Cholylglycylamidofluorescein is composed of Cholic acid conjugated via a glycylamino linkage to fluorescein. (Ex/Em = 492/515 nM in Aqueous)
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DC76936 Cholesterol sulfate
Cholesterol sulfate is a DOCK2 inhibitor. Cholesterol sulfate has an IC50 value of 2 μM for mouse DOCK2. Cholesterol sulfate can be used in studies such as immunity and inflammation.
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DC76935 Cetoleic acid
Cetoleic acid is a long-chain monounsaturated fatty acid found in deep-sea fish. Cetoleic acid can promote the synthesis of ALA in human HepG2 cells and EPA in vitro in salmon liver cells, affecting cholesterol levels in rodents. Cetoleic acid has potential applications in cardiovascular disease research.
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DC76934 C32 Ceramide
C32 Ceramide is a naturally occurring ceramide that has been found in the stratum corneum of human and nude mouse skin.
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DC76933 C22 Ceramide (d18:1(14Z)/22:0)
C22 Ceramide (d18:1(14Z)/22:0) is an endogenous bioactive sphingolipid. C22 Ceramide (d18:1(14Z)/22:0) has the effects of promoting cell cycle arrest and inducing apoptosis.
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DC76932 C16 Galactosylceramide
C16 Galactosylceramide is a sphingolipid compound. C16 Galactosylceramide participates in the physiological processes of lipid metabolism and immune regulation in cells. C16 Galactosylceramide can be used in the study of diabetes.
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DC76931 Bufotenidine iodide
Bufotenidine iodide is a component found in toad venom and belongs to the indole alkaloid class.
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DC76930 Benzoyl coenzyme A sodium
Benzoyl coenzyme A (sodium) is the sodium salt form of Benzoyl coenzyme A. AMG 193 is an orally active MTA-cooperative PRMT5 inhibitor with antitumor activity. AMG 193, when complexed with MTA, preferentially inhibits the growth of MTAP-deficient tumor cells by inhibiting PRMT5 (IC50=0.107 μM), thereby protecting normal cells with wild-type MTAP.
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DC76929 Bazedoxifene N-Oxide
Bazedoxifene N-Oxide is the oxidative degradation product of selective estrogen receptor modulator (SERM) Bazedoxifene.
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DC76928 Aspinolide B
Aspinolide B is a pentaketide and a 10-membered lactone with plant growth regulatory activity, which can be extracted from Aspergillus ochraceus. Aspinolide B promotes the growth of lateral roots in S. lycopersicum and can be utilized in related research.
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DC76927 Arimistane
Arimistane is a metabolite of 7-oxo-DHEA and can be used as a diagnostic marker of 7-oxo-DHEA administration.Arimistane is a metabolite of 7-oxo-DHEA and can be used as a diagnostic marker of 7-oxo-DHEA administration.
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DC76926 Amiquinsin hydrochloride monohydrate
Amiquinsin hydrochloride monohydrate is a compound with hypotensive activity. Amiquinsin hydrochloride monohydrate is metabolized in vivo, and the major metabolite is 4-amino-6,7-dimethoxy-3-quinolinol hydrochloride hydrate.
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DC76925 Acremine F
Acremine F is a fungal metabolite that has been found in Acremonium.
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DC76924 8-Oxo-dATP lithium
8-Oxo-dATP lithium, as an oxidized purine nucleoside triphosphate, is hydrolyzed by MTH1 into monophosphates, thereby preventing errors caused by its misincorporation during DNA replication or transcription.
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DC76923 8-Bromo-2'-deoxy-ATP tetrasodium
8-Bromo-2'-deoxy-ATP (8-Bromo-dATP) tetrasodium is a derivative of the nucleoside triphosphate 2'-Deoxyadenosine-5'-triphosphate (dATP).
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DC76922 8-Aminoguanine
8-Aminoguanine is a endogenous purine. 8-Aminoguanine inhibits PNPase (purine nucleoside phosphorylase). 8-Aminoguanine induces diuresis/natriuresis/glucosuria.
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DC76921 6-Hydroxy bexarotene
6-Hydroxy bexarotene is the main circulating metabolite of bexarotene, found in rats, dogs, and humans. Compared to the parent compound, 6-hydroxy-bexarotene shows a significantly reduced ability to bind to retinoid receptors and exhibits very minimal activity in activating retinoic acid receptors.
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DC76920 5-Androstenetriol
5-Androstenetriol is a systemic radiation protector that can boost the host's immunity, leading to increased resistance to infections. 5-Androstenetriol can raise levels of IL-2, IL-3, and IFN, while countering the immunosuppressive effects of Hydrocortisone.
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DC76919 4-Hydroxyphenylpropionylglycine
4-Hydroxyphenylpropionylglycine is a metabolite of the conditionally essential amino acid Tyrosine.
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DC76918 3-Oxochenodeoxycholic acid
3-Oxochenodeoxycholic acid is an endogenous metabolite that can be found in feces. 3-Oxochenodeoxycholic acid can serve as an indicator for the diagnosis of certain diseases, such as COVID-19.
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DC76917 3-Methyl-2-butenal
3-Methyl-2-butenal (3-Methylbut-2-en-1-al) can be isolated from hops.
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DC76916 3-Hydroxylidocaine
3-Hydroxylidocaine is the major metabolite of Lidocaine in rats and sheep.
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DC76915 3-Epideoxycholic acid
3-Epideoxycholic acid is the microbial metabolite of Deoxycholic acid. 3-Epideoxycholic acid targets FXR of dendritic cells, reduces their immunostimulatory properties, promotes the generation of Treg cells, and exhibits anti-inflammatory activity. 3-Epideoxycholic acid promotes the growth of bacteria Bacteroides.
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DC76914 3-cis-Hydroxyglibenclamide
3-cis-Hydroxyglibenclamide is the metabolism of Glibenclamid.
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