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Home > Inhibitors & Agonists > Metabolic Enzyme/Protease > Endogenous Metabolite

Endogenous Metabolite

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Cat. No. Product Name Field of Application Chemical Structure
DC76973 Δ2-trans-Hexadecenoic acid
Δ2-trans-Hexadecenoic acid is a trans fatty acid isolated from the seed oil of Aster tataricus (Thunb.).
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DC76972 Tribromobisphenol A
Tribromobisphenol A (Tri-BBPA; 2,2',6-Tribromobisphenol A) is a phenolic compound isolated from human breast milk.
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DC76971 Thalicpureine
Thalicpureine (compound 12) is a secondary metabolite.
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DC76970 Succinyl CoA
Succinyl CoA is an intermediate of the citric acid cycle. Succinyl CoA can be converted to succinic acid and can also combines with glycine to form δ-amino levulinic acid (ALA) to synthesize porphyrins (heme). Succinyl CoA can be used in the study of metabolic, neurological and haematological abnormalities (such as porphyrias) caused by nutritional vitamin B12 deficiency (resulting in a deficiency in Succinyl CoA synthesis).
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DC76969 SPP-037
SPP-037 is an orally active and selective inhibitor of ST6GAL1 (IC50: 3.59 μM). SPP-037 exhibits anti-MDA-MB-231 cell migration activity by inhibiting integrin α2,6-sialylation and integrin-FAK-paxillin pathway. SPP-037 has anti-tumor activity in MDA-MB-231 xenograft mouse model. SPP-037 can be used in breast cancer research.
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DC76968 Ribulose 1,5-bisphosphate
Ribulose 1,5-bisphosphate (RuBP) is an intermediate in photosynthesis that can be metabolized to 3-phosphoglycerate by ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco), a key enzyme in the Calvin-Benson-Bassham cycle.
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DC76967 Resolvin E4
Resolvin E4 (RvE4) is an endogenous metabolite that stimulates efferocytosis of apoptotic neutrophils and senescent erythrocytes. Resolvin E4 enhances resolution of hemorrhagic exudates and inflammation in vivo.
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DC76966 Remisporine B
Remisporine B is a polyketide, that can be isolated from Penicillium sp. ZJ-SY2. Remisporine B exhibits immunosuppressive efficacy, that inhibits concanavalin A-induced T-cell proliferation and LPS- induced B-cell proliferations of mouse splenic lymphocytes with IC50 of 30.1 µg/mL and 32.4 µg/mL.
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DC76965 Pyridoxine tri(2-hexyldecanoate)
Pyridoxine tri(2-hexyldecanoate) is a derivative of Vitamin B6 and activates the GTPase activity of microtubules[1][2].
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DC76964 Pseudane V
Pseudane V is the secondary metabolite that can be isolated from the marine bacterium Pseudoalteromonas sp. M2. Pseudane V inhibits the melanin synthesis in cell Melan-A, and can be used as a potential skin whitening agent.
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DC76963 Propiverine N-oxide
Propiverine N-oxide is the main metabolite of hydrochloride propiverine, and it can affect bladder contractions and saliva secretion in small pigs.
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DC76962 Previridicatumtoxin
Previridicatumtoxin is a fungal metabolite with antibacterial and anticancer activities. Previridicatumtoxin can be extracted from P. aethiopicum and utilized in research related to cancer as well as infections.
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DC76961 PD-147693
PD-147693 (compound II) is an active metabolite of the presynaptic dopamine autoreceptor agonist CI-1007 and has antipsychotic activity similar to CI-1007.
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DC76960 O-Deshydroxyethyl bosentan
O-Deshydroxyethyl bosentan is a metabolite of Bosentan, which is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors.
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DC76959 Nepetalactone
Nepetalactone is an unsaturated lactone that may be hydrolyzed to nepetalic acid.
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DC76958 N-Cholyl-L-alanine
N-Cholyl-L-alanine is a bile acid amidate, which is found in human fecal samples.
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DC76957 N-Butyl lithocholic acid
N-Butyl lithocholic acid is a derivative of the secondary bile acid Lithocholic acid.
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DC76956 Mevalonate 5-phosphate trilithium
Mevalonate 5-phosphate trilithium is a substrate of phosphomevalonate kinase and mevalonate-5-phosphate decarboxylase.
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DC76955 Mannose 6 phosphate
Mannose 6 phosphate is a source of energy for cellular metabolism through their involvement in glycolysis. Mannose 6 phosphate can protect proteins in the dermis scaffold against oxidation and degradation. Mannose 6 phosphate can reverse the visible signs of aging.
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DC76954 LysoPC(16:1(9Z))
LysoPC(16:1(9Z)) is a type of lysophosphatidylcholine that can be used to study spleen deficiency syndrome.
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DC76953 LY-195448
LY-195448 is a phenethanolamine that exhibits anti-tumour activity across various murine tumour models.
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DC76952 Lunularic acid
Lunularic acid is a dihydrostilbene compound with anti-hyaluronidase activity (IC50: 0.13 nM). Lunularic acid can be used as an endogenous growth inhibitor in liverworts, replacing the function of abscisic acid in higher plants.
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DC76951 LacCer (d18:1/16:0)
LacCer (d18:1/16:0) (C16 Lactosylceramide (d18:1/16:0)) is an endogenous bioactive sphingolipid that can form membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs). The levels of LacCer (d18:1/16:0) are elevated in the plasma of insulin-resistant cattle. In a mouse model of Niemann-Pick type C1 disease (a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder), the expression of LacCer (d18:1/16:0) is also upregulated. LacCer (d18:1/16:0) can be used in research on metabolic diseases and neurodegenerative diseases.
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DC76950 Histamine-15N3
Histamine-15N3 is the 15N3-labeled Histamine. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter.
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DC76949 Fluorocurarine chloride
Fluorocurarine chloride (Metvine; Vincanine methyl chloride) is a plant metabolite that can be isolated from Catharanthus roseus.
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DC76948 Etiocholanolone glucuronide
Etiocholanolone glucuronide (Etio-G) is the metabolite of Etiocholanolone. 4'-Fluorouridine triphosphate can effectively bind to RSV RdRP.
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DC76947 Ethyl 3-methyl-2-butenoate
Ethyl 3-methyl-2-butenoate is a volatile compound that can be isolated from sea buckthorn.
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DC76946 Epothilone C
Epothilone C is a polyketide natural product. Epothilone C is produced by the combined action of one nonribosomal peptide synthetase (NRPS) and nine polyketide synthase (PKS) modules in a multienzyme system. Epothilone C can be used for tumor research.
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DC76945 Docosahexaenoyl-L-carnitine chloride
Docosahexaenoyl-L-carnitine chloride is a long-chain acylcarnitine composed of Docosahexaenoic acid and L-carnitine. Docosahexaenoyl-L-carnitine chloride is transported into mitochondria for β -oxidation and decomposition under the action of carnitine palmitoyltransferase I (CPT I) and others. Docosahexaenoyl-L-carnitine chloride is promising for research of diseases related to fatty acid metabolism.
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DC76944 Dihydromevinolin
Dihydromevinolin is a potent hypocholesterolemic metabolite produced by Aspergillus terreus. Dihydromevinolin is a HMG-CoA reductase inhibitor.
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