Tri-GalNAc(OAc)3 Cbz |CAS 1159408-63-5|DC Chemicals

Cas No.:	1159408-63-5
Chemical Name:	5-Oxa-2,9,13-triazaoctadecanoic acid, 8,14-dioxo-3,3-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-18-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-, phenylmethyl ester
Synonyms:	A-D-galactopyranosyl]oxy]-, phenylmethyl ester;[(2R,3R,4R,5R,6R)-5-acetamido-6-[5-[3-[3-[3-[3-[3-[5-[(2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetyloxy-6;5-Oxa-2,9,13-triazaoctadecanoic acid, 8,14-dioxo-3,3-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-18-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-, phenylmethyl ester;Triantennary GalNac Ligand Building block;Triantennary GalNAc Ligand;5-?Oxa-?2,?9,?13-?triazaoctadecanoic acid, 8,?14-?dioxo-?3,?3-?bis[[3-?oxo-?3-?[[3-?[[1-?oxo-?5-?[[3,?4,?6-?tri-?O-?acetyl-?2-?(acetylamino)?-?2-?deoxy-?β-?D-?galactopyranosyl]?oxy]?pentyl]?amino]?propyl]?amino]?propoxy]?methyl]?-?18-?[[3,?4,?6-?tri-?O-?acetyl-?2-?(acetylamino)?-?2-?deoxy-?β-?D-?galactopyranosyl]?oxy]?-?, phenylmethyl ester;Tri-GalNAc(OAc)3 Cbz
SMILES:	O1[C@H]([C@@H]([C@H]([C@H]([C@H]1COC(C)=O)OC(C)=O)OC(C)=O)NC(C)=O)OCCCCC(NCCCNC(CCOCC(COCCC(NCCCNC(CCCCO[C@H]1[C@H]([C@H]([C@H]([C@@H](COC(C)=O)O1)OC(C)=O)OC(C)=O)NC(C)=O)=O)=O)(COCCC(NCCCNC(CCCCO[C@H]1[C@@H]([C@H]([C@H]([C@@H](COC(C)=O)O1)OC(C)=O)OC(C)=O)NC(C)=O)=O)=O)NC(=O)OCC1C=CC=CC=1)=O)=O
Formula:	C₈₇H₁₃₄N₁₀O₃₈
M.Wt:	1928.03908777237
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC67352	C12-Diacid-Tri-GalNAc-COOH
DC67351	Tri-GalNAc(OAc)3 Cbz	Tri-GalNAc(OAc)3 Cbz is a ligand for asialoglycoprotein receptor (ASGPR) where the sugars are protected by acetylation and the tris tertiary amine is protected by benzyloxycarbonyloxy (Cbz). This peracetylated tri-GalNAc(OAc)3 Cbz can be serve as a valuable building block for ASGPR-targeted therapies. Its three branches or arms, each ending in a GalNAc sugar, ensure strong binding to hepatocyte ASGPR. However, the key feature lies in its protective groups: acetylated sugars allow for controlled removal to expose reactive sites for conjugation, while the Cbz-protected amine provides stability and can be selectively cleaved to introduce a reactive amine group for further biomolecule attachment, ultimately enabling researchers to tailor tri-GalNAc(OAc)3 Cbz into customized conjugates for specific therapeutic applications.
DC67296	Galnac GLS-15	GLS-15 is a novel GalNAc-derived small molecule structure designed for siRNA delivery.
DC66575	Peracetylated GalNAc PEG linker-Acid-2
DC66574	Peracetylated GalNAc-L96-1
DC66572	Peracetylated GalNAc PEG linker-Amino-2
DC66569	GalNAc-L96-Amide
DC66568	Peracetylated GalNAc PEG linker-Amino-1
DC66565	Peracetylated GalNAc-L96-Acid-1
DC66564	Peracetylated GalNAc PEG linker-Acid-1