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BI 703704

  Cat. No.:  DC11995  
Chemical Structure
1423067-48-4
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More than 5000 active chemicals with high quality for research!
Field of application
A novel potent soluble guanylate cyclase (sGC) activator.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1423067-48-4
Chemical Name: (1R,5S,8s)-3-(4-(5-methyl-2-((2-methyl-4-(piperidine-1-carbonyl)benzyl)oxy)phenyl)thiazol-2-yl)-3-azabicyclo[3.2.1]octane-8-carboxylic acid
Synonyms: BI-703704;BI703704
SMILES: [C@@]([H])12[C@H](C(O)=O)[C@@]([H])(CC1)CN(C1=NC(C3=CC(C)=CC=C3OCC3=CC=C(C(N4CCCCC4)=O)C=C3C)=CS1)C2
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: A novel potent soluble guanylate cyclase (sGC) activator; reduces progression of renal damage in the ZSF1 rat, shows the potential as an effective therapy for diabetic nephropathy.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC47004 Mosliciguat Mosliciguat is a guanylate cyclase activator.
DC46515 MM 419447 MM 419447, a linaclotide metabolite, is a guanylate cyclase-C agonist. MM 419447 has the potential for the research of the irritable bowel syndrome with constipation (IBS-C).
DC44916 Guanylate cyclase-IN-1 Guanylate cyclase-IN-1 (Example 46) is a guanylate cyclase inhibitor that can be used for cardiovascular diseases research.
DC41630 Guanylin(human) TFA Guanylin(human) TFA, a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin(human) TFA is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism.
DC41629 Guanylin(human) Guanylin(human), a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin(human) is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism.
DC7787 NS-2028 NS 2028 is a specific inhibitor of soluble guanylyl cyclase.
DC11995 BI 703704 A novel potent soluble guanylate cyclase (sGC) activator.
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