Alternariol is a mycotoxin, topoisomerase I and II inhibitor and potential ER agonist found in Alternaria.

Acepromazine maleate, also known as Sch-10649, is a dopamine D1/2 receptor and 5-HT1A/2A receptor antagonist used to prevent nausea and induce sedation. Acepromazine maleate is discontinued.

Pramiverin HCl is a bioactive chemical.

MS4 is a novel glucocorticoid receptor (GR) agonist with anti-inflammatory activity and displaying reduced impact on islets.

Nevirapine-d3 is deuterized nevirapine, reducing P450 metabolite formation, impacting on phase II metabolism and hepatocyte protein expression.

Garcinoic Acid is a natural and selective agonist of pregnane X receptor.

Levothyroxine sodium is a thyroid hormone.

Oxacillin (trade name Bactocill) is a narrow-spectrum beta-lactam antibiotic of the penicillin class developed by Beecham. It was patented in 1960 and approved for medical use in 1962. Oxacillin is a penicillinase-resistant β-lactam. It is similar to methicillin, and has replaced methicillin in clinical use.

Nafcillin sodium is an antibacterial chemical.

Niclosamide-olamine is a Insect Attractant, Repellent and Chemosterilant.

MRK-740 is a novel potent (IC50: 80?±?16?nM), selective and cell-active PRDM9 inhibitor, specifically and directly inhibiting H3K4 methylation at endogenous PRDM9 target loci.

NPE-caged-HPTS is a caged fluorescent pH indicator, rapidly releasing the fluorophore HPTS (pKa 7.25) upon two-photon excitation (>3000 s-1).

CRBN-6-5-5-VHL is a novel cell-permeable, potent and selective cereblon degrader.

COH34 S-dioxide is an oxidized analog of COH34

C620-0696 is a novel potent inhibitor of bromodomain PHD-finger transcription factor (BPTF).

ZK93426 is a potent, selective and competitive benzodiazepine receptor antagonist (IC50 values are 0.4 and 0.7 nM for inhibition of [3H]-flunitrazepam binding to rat cerebellum and hippocampus respectively)

ZK93423 is a potent benzodiazepine receptor agonist (IC50 = 1 nM). ZK93423 is non-selective between α1-, α2-, α3- and α5-subunit containing GABAA receptors (Ki values are 4.1, 4.2, 6 and 4.5 nM for inhibition of [3H]Ro15-1788 binding to human recombinant α1β3γ2, α2β3γ2, α3β3γ2 and α5β3γ2 receptors respectively).

YS121 is a dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase.

YM976 is an orally active PDE4 inhibitor (IC50 = 2.2 nM). YM976 has low emetogenic activity, suggested to be due to poor brain penetration.

XAP044 is a potent and selective mGlu7 antagonist (IC50 = 88 nM). It inhibits lateral amygdala long term potentiation (LTP) in brain slices from wild type mice. XAP044 displays no effects on the LTP of mGlu7 deficient mice.

WIN 64338 hydrochloride is a potent, non-peptide, competitive bradykinin B2 receptor antagonist.WIN 64338 inhibits [3H]-bradykinin binding on guinea pig trachea with nanomolar affinity but is not active in the rabbit aorta (the classical bradykinin B1 preparation).

WB 4101 hydrochloride is a α1A-adrenergic selective antagonist.

VU0424465 is a potent mGlu5 positive allosteric modulator and agonist

DCPIB is a novel Inhibitor of Volume-Regulated Anion Channels, Distinctly Modulating K2P Channels.

VU0285683 is a negative allosteric modulator of mGlu5 receptors. VU0285683 acts as a full antagonist and blocks the glutamate response to mGlu5 (IC50 = 24.4 nM). VU0285683 is selective for mGlu5 over mGlu1, mGlu3 and mGlu4.

VRT-532 is a CFTR modulator for the treatment of cystic fibrosis.

U69593 is a a selective KOR-1 (κ1-opioid receptor) agonist. U-69593 is known to inhibit cocaine sensitization in meso-limbic dopamine neurons by normalizing basal overflow of dopamine.

TG6-129 is an antagonist of the EP2 receptor, suppressing PGE2-induced elevation of cAMP in cells expressing EP2 with an IC50 value of 1.6 μM. It is without effect on EP4, DP1, IP, and β2-adrenergic receptors. TG6-129 reduces the expression of COX-2, IL-1β, IL-12, IL-23, IL-6, and TNF-α induced by the EP2-selective agonist butaprost in P388D1 macrophages.

SSR 146977 is a new potent nonpeptide tachykinin NK3 receptor antagonist.

SQ-29548 is a highly selective TP receptor antagonist which binds to the human recombinant TP receptor with a Ki of 4.1 nM. SQ-29548 inhibits the aggregation of washed human platelets induced by U-46619 with an IC50 of 0.06 μM.