Vapreotide acetate is a synthetic analog of somatostatin for the treatment of variceal bleeding; also exhibits antitumor activity.

Vapendavir (BTA798) is a novel potent enteroviral capsid binder, inhibits EV71 replication of all isolates with mean EC50 of 0.7 uM.

Vanoxerine (GBR-12909, I-893, Boxeprazine) is a highly potent inhibitor of dopamine uptake in vitro in tissue slices obtained from rat neostriatum with IC50 of 40-50 nM, also inhibits norepinephrine uptake with IC50 of 560-2600 nM.

Valsartan is a nonpeptide angiotensin II AT1-receptor antagonist with an IC50 ranging from 39.5 to 116 μM. This in turn causes blood vessel dilation.

Valganciclovir (hydrochloride), the L-valyl ester of ganciclovir, is actually a prodrug for ganciclovir.

Valdecoxib (SC 65872) is a COX-2 selective inhibitor with an IC50 value of 5 nM.

Valategrast hydrochloride is a potent, α4β1 (VLA-4) and α4β7 dual antagonist..

Valategrast (R411), a small molecule antagonist of α4β1 integrin, represents a potential therapy for asthma

Valacyclovir is an antiviral agent that acts as a very potent inhibitor of viral DNA polymerase.

Valaciclovir HCl

Vaborbactam is a cyclic boronic acid pharmacophore β-lactamase inhibitor.

Vabicaserin hydrochloride is a 5-hydroxytryptamine 2C (5-HT2C) receptor-selective agonist with an EC50 of 8 nM.

V-116517 is a novel potent, selective, oral bioavailable TRPV1 antagonist with IC50 of 35.1 nM.

V-11-0711 (V-11 0711) is a novel potent and selective choline kinase alpha (ChoKα) inhibitor with IC50 of 20 nM, with 11 fold less activity against ChoKβ.

UU-T01 is a novel small-molecule inhibitor of β-catenin/Tcf4 protein-protein interaction with Ki of 3.14 uM, binds to β-catenin with Kd of 0.531 uM..

USP7/USP47 inhibitor is a potent and dual inhibitor of USP7/USP47 with IC50s of 0.42 uM(USP7) and 1.0 uM(USP47).

USP25 and 28 inhibitor AZ-2 is a potent, selective, dual USP25/28 inhibitor with IC50 of 0.9/0.9 uM, respectively.

USP10-IN-9 is a HBX19818 analog, selective USP10 inhibitor with IC50 similar to HBX19818, but does not inhibit USP7 (IC50>100 uM)..

UR-PI376 is a potent, selective histamine H4 receptor (hH4R) agonist with pEC50 of 7.47, shows negligible hH1R and hH2R activities and significant selectivity over the hH3R..

Uridine-5'-triphosphate (UTP) is a pyrimidine nucleoside triphosphate and a substrate for the synthesis of RNA during transcription.

Uridine 5'-monophosphate is a nucleotide that is used as a monomer in RNA.

URB754 is reported to be a potent, noncompetitive inhibitor of monoacylglycerol lipase (MAGL), exhibiting an IC50 of 200 nM for the recombinant rat brain enzyme.

UPF1854 is a potent tankyrase inhibitor with IC50 of 12 nM and 200 nM for TNKS1 and TNKS-2 respectively, displays no cross-reactivity versus other PARP proteins.

UPC-K-005 is a novel p38 inhibitor, exhibiting a IC50 of 13 μM.

UniPR1331 (UniPR-1331) is a selective, orally available antagonist of Eph/ephrin interaction with pIC50 of 5.45, IC50 of 2.9 uM.

UNC4203 (UNC-4203) is a potent, highly selective MerTK with IC50 of 2.4 nM, displays >30- and 4 -foldfold selectivity over Alx (IC50=80 nM) and Tyro3 (IC50=9.1 nM).

UNC-2170 is a small molecule ligand for the methyl-lysine binding protein 53BP1 (p53-binding protein 1) with Kd of 22 uM against the 53BP1 tandem tudor domain.

UNC1666 is a potent, specific dual Mer and Flt3 tyrosine kinase inhibitor with IC50 of 0.55 and 0.69 nM.

UNC119-Src interaction inhibitor 3 is a potent, specific small molecule inhibitor of UNC119-Src interaction with IC50 of 12 nM for displacement of the Src peptide from UNC119A.

UNC-1062 is a potent and selective Mer kinase inhibitor with IC50 of 1.1 nM, Ki of 0.33 nM.