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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DC21102 GW 275175X
GW 275175X is a derivative of BDCRB that displays anti-HCMV activity by inhibition of viral DNA maturation.
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DC9458 GW-1100
GW 1100 is a selective antagonist of GPR40-mediated Ca2+ elevations in HEK293 cells stimulated by GW 9508 (an agonist of both GPR40 and GPR120, another GPCR activated by long chain fatty acids) or linoleic acid with a pIC50 value equal to 5.99.
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DC23117 GV-58
GV-58 is a potent, selective N-Type and P/Q-type Ca2+ Channel agonist with EC50 of 7.2 and 8.8 uM, shows no acitivity for L-type calcium channels (EC50>100 uM).
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DC23297 GUT-70
GUT-70 is a tricyclic coumarin derived from Calophyllum brasiliense, markedly reduces cell proliferation, viability through G1 cell cycle arrest and increases apoptosis.
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DC12076 Guanidinosuccinic acid
Guanidinosuccinic acid is a nitrogenous metabolite isolated in excess from serum and urine.
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DC10233 Guanfacine Hydrochloride
Guanfacine Hydrochloride is a selective α2A-adrenoceptor agonist with anti-hypertensive effect.
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DCAPI1387 Guaifenesin(Guaiphenesin)
Guaifenesin(Guaiphenesin)
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DC21404 GTC 365 hydrochloride
GTC-365 (NSC 177365) is a small drug-like pharmacological chaperone that induces cancer cell death by restoring tertiary DNA structures in mutant human telomerase reverse transcriptase (hTERT) promoters.
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DC21403 GTC 365
GTC-365 (NSC 177365) is a small drug-like pharmacological chaperone that induces cancer cell death by restoring tertiary DNA structures in mutant human telomerase reverse transcriptase (hTERT) promoters.
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DC20399 GSTO1 inhibitor C1-27
GSTO1 inhibitor C1-27 is a potent, selective, covalent glutathione S-transferase omega 1 (GSTO1) inhibitor with IC50 of 31 nM.
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DC23886 GSM-2
GSM-2 is a second-generation γ-secretase modulator (GSM) that only decreases Aβ42 (IC50=65.2 nM), while inversely increasing Aβ38 and having no effect on β-CTF and Aβ40 levels.
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DC23890 GSM-1
GSM-1 (GSM1) is a γ-secretase modulator that directly targets the transmembrane domain (TMD) 1 of presenilin 1, shows potent Aβ42-lowering effect (IC50=0.348 uM) in a cell-based assay.
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DC9712 Iinerixibat
GSK2330672 is a highly potent, nonabsorbable ASBT(apical sodium-dependent bile acid transporter) inhibitor (hASBT IC50=42 ± 3 nM) .
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DC9944 PI3Kδ inhibitor GS2292767
GSK2292767 is a potent and selective PI3Kδ inhibitor.
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DC9943 PI3Kδ inhibitor GS2269557
GSK-2269557 is a potent and selective PI3Kδ inhibitor over the closely related isoforms.
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DC2069 IGF-1R inhibitor GS1904529A
GSK1904529A is a selective inhibitor of IGF-1R and IR with IC50 of 27 nM and 25 nM, respectively.
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DC9515 PI3K inhibitor GS1059615
GSK1059615 is a dual inhibitor of PI3Kα/β/δ/γ (reversible) and mTOR with IC50 of 0.4 nM/0.6 nM/2 nM/5 nM and 12 nM, respectively.
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DC11297 GS-9822
GS-9822 is a novel, potent NCINI with a higher barrier to resistance relative to early prototype NCINIs, including GS-9695.
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DC23244 GS-9695
GS-9695 is a potent, non-catalytic site HIV integrase inhibitor with wild type EC50 of 1.2 nM..
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DC21071 GS-9451
GS-9451 (Vedroprevir) is a potent HCV NS3/4A protease inhibitor with Ki of 0.41 nM, inhibits HCV GT-1b NS3/4A with IC50 of 3.2 nM in enzymatic assays.
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DC23381 GS-626510
GS-626510 (GS-6510, GS 6510, GS 626510) is a novel BET family bromodomains inhibitor with Kd of 0.5-2.8 nM for BRD2/3/4, and BRDT.
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DC21068 GS-493
GS-493 is a novel potent, selective SHP2 inhibitor with IC50 of 71±15 nM in enzyme assay.
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DC21070 GS-1
GS-1 is a close structural analog of GS-5806 that acts an RSV fusion inhibitor.
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DC23564 GS 462808
GS 462808 is a potent Late INa current inhibitor with IC50 of 1.33 uM.
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DCAPI1367 Grape Seed Extract
Grape Seed Extract
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DC9080 Granisetron HCl
Granisetron Hcl(BRL 43694A) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.
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DC9918 Gracillin
Gracillin is a kind of steroidal saponin isolated from the root bark of wild yam Dioscorea nipponica with antitumor agent.
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DC21065 GR-64349
GR-64349 is a potent and selective tachykinin NK2 receptor agonist with EC50 of 3.7 nM, displays >1000- and >300-fold selectivity over NK1 and NK3 receptors, respectively..
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DC11090 GR3027 Featured
GR3027 (Golexanolone) is a GABA-A receptor modulating steroid antagonist that selectively antagonizes the enhanced activation of GABAA receptors by neurosteroids such as allopregnanolone and THDOC.
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DC8820 GR148672X
GR148672X is a specific TGH inhibitor.
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