Novel inhibitor of the human enzyme dimethylarginine dimethylaminohydrolase-1 (DDAH-1)

Potent and selective CLK1 and CLK2 inhibitor

Potent CLK1 and CLK2 inhibitor, also inhibiting SRPK1 and SRPK2

Prostaglandin I2 analogue, dose-dependently inhibiting human and rabbit platelet aggregation and human platelet adhesion in vitro

Novel hypoxia-inducible factor (HIF)-1 inhibitor

Antibiotic, acting as a mechanism-based β-lactamase inhibitor

Novel two-photon polarity-sensitive lipid membrane probe

Natural modulator of voltage-gated sodium (NaV) channels

The most potent clathrin terminal domain-amphiphysin inhibitor reported to date

Novel protein tyrosine phosphatase-1B (PTP1B) inhibitor, neutralizing the toxicity of α-hemolysin, inhibiting β-secretase 1 (BACE1)-mediated insulin receptor cleavage

Inhibitor of respiratory syncytial virus (RSV)

Inhibitor of H5N1 avian influenza A virus infection

Negative control for CK156

Natural Dual Inhibitor for Wild Type and D816V Mutant of c-KIT Kinase

Inhibitor of vascular adhesion molecule-1 (VCAM-1), HMGB1 phosphorylation, iNOS expression, NFkB activation; Antiinflammatory

Novel inhibitor of CK2α, binding in the ATP pocket

Novel cell-permeable and selective inhibitor of human protein kinase CK2, inducing apoptosis in the prostate cancer cell line LNCaP

Novel potent and selective inhibitor of CK2. modulating the aforementioned signaling cascades and counteracting 17-AAG-mediated up-regulation of HSP70 in brain cancer cells

Novel CK2 inhibitor, targeting an allosteric pocket, exhibiting an IC50 of 3.4 μM against purified CK2α in combination with a favorable selectivity profile

Novel potent CK2 inhibitor

Potent, reversible, and ATP-competitive inhibitor of casein kinase-2 (CK2)

Novel selective allosteric modulator of the protein kinase CK2, inducing apoptosis and cell death in 786-O renal cell carcinoma cells (EC50 = 5 µM) and inhibiting STAT3 activation even more potently than the ATP-competitive drug candidate CX-4945

Novel potent PfNDH2 inhibitor

Novel CK2 inhibitor, showing potent CSC inhibitory effects in A549 cells

Long-lasting stimulator of the production of growth hormone (GH) from the pituitary gland

Stimulator of the production of growth hormone (GH) from the pituitary gland

Novel inhibitor of STAT3 activation and dimerization through targeting the phosphotyrosine binding site within the SH2 domain

Anti-HIF-1alpha agent, inhibiting HIF-1alpha and cellular VEGF proteins

Novel non-ATP competitive allosteric inhibitor of Aurora B kinase, binding in the allosteric site F

SecA inhibitor, showing antiprotozoal, antibacterial and antifungal effects, inhibiting post-translational protein transport into the endoplasmic reticulum. also Inhibiting ATP-dependant translocation of precursor proteins acrossing a bacterial cell membr