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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCAPI1372 Ciprofloxacin (Cipro) Featured
Ciprofloxacin (Bay-09867) is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
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DC10868 Cilofexor Featured
Cilofexor (GS-9674, GS9674) is novel specific, non-steroidal farnesoid X receptor (FXR) agonist that reduces liver fibrosis and ameliorates portal hypertension in rat NASH models.
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DC7561 Cilengitide (TFA salt) Featured
Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.
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DC9488 Cilengitide Featured
Cilengitide (EMD 121974; NSC 707544) is a potent integrin inhibitor for αvβ3 and αvβ5 integrin with IC50 of 4.1 nM and 79 nM, respectively; ~10-fold selectivity against gpIIbIIIa.
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DCAPI1021 Cidofovir(Vistide) Featured
Cidofovir(Vistide)
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DC7976 CID 797718 Featured
CID-797718 is a compound with unknown details.
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DC9955 BCL6 inhibitor(CID5721353) Featured
CID5721353 is a B-Cell Lymphoma 6 Inhibitor (BCL6 inhibitor).
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DC10574 CID-25014542
CID-25014542 is novel inhibitor of Raf kinases.
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DC7253 CID-2011756 Featured
CID-2011756 is a cell-active ATP competitive and specific PKD1 inhibitor that inhibits phorbol ester-induced endogenous PKD1 activation in LNCaP prostate cancer cells.
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DC10873 CID16020046 Featured
CID 16020046 is a potent and selective GPR55(LPI receptor) antagonist; inhibitsGPR55 constitutive activity with IC50 of 0.15 uM.
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DC2060 CI994 (Tacedinaline) Featured
CI994 (Tacedinaline) is an anti-cancer drug which inhibits HDAC1 with IC50 of 0.57 μM.
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DC8139 GMX1778(CHS-828) Featured
CHS-828 is a pyridyl cyanoguanidine anti-tumor agent that has been identified as a competitive inhibitor of Nampt as well as an inhibitor of NF-κB pathway activity.
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DC8116 Tosedostat (CHR2797) Featured
CHR-2797 is an aminopeptidase inhibitor, with IC50 values of 100 nM for LAP3 (LAP), 150 nM for PSAP (PuSA) and 220 nM for CD13 (Aminopeptidase N).
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DC9082 Chlorpromazine HCl Featured
Chlorpromazine Hydrochloride is a dopamine and potassium channel inhibitor used as the prototypical phenothiazine antipsychotic drug.
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DC7384 CHIR-98014 Featured
CHIR-98014 is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2.
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DC9292 CHIR-090 Featured
CHIR-090 is a potent LpxC inhibitor, displays two-step time-dependent inhibition and kills a wide range of Gram-negative pathogens as effectively as ciprofloxacin or tobramycin.
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DC7978 Tucidinostat(Chidamide) Featured
Chidamide is a class I HDAC inhibitor with IC50s of 95/160/67/733 nM for HDAC1/2/3/8; also inhibits HDAC10/11(IC50=78/432 nM); no inhibition on HDAC4/5/7/9/6(IC50>30 uM).
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DC7383 CH5424802(Alectinib) Featured
CH5424802(AF 802; Alectinib) is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive to L1196M mutation.
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DC7939 CH-223191 Featured
CH-223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor.
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DC10722 CGP-71683A Featured
CGP 71683A is a potent and highly selective non-peptide antagonist of the NPY Y(5) receptor in the study of obesity.
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DC7381 CGP-57380 Featured
CGP 57380 is a cell-permeable pyrazolo-pyrimidine compound that acts as a selective inhibitor of Mnk1 (IC50 = 2.2 μM) with no inhibitory activity against p38, JNK1, ERK1/2, PKC, or Src-like kinases.
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DC10843 CGP 52432 Featured
CGP 52432 is a potent, selective GABAB receptor antagonist (IC50 = 85 nM).
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DC7101 CGK733 Featured
CGK 733 is a potent and selective inhibitor of ATM/ATR with IC50 of ~200 nM.
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DC7039 CFTR Inhibitor II Featured
CFTR Inhibitor II is a cell-permeable glycinyl hydrazone compound that acts as a potent, selective and reversible open-channel blocker of CFTR with intermediate speed (< 1 min; 95% inhibition at 50 µM; Ki = 4.3 µM in CFTR-expressing FRT cells.
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DC9154 Cetirizine 2HCl
Cetirizine 2Hcl, a second-generation antihistamine, is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist used in the treatment of allergies, hay fever, angioedema, and urticaria.
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DC7814 Cerdulatinib(PRT-062070; PRT2070) Featured
Cerdulatinib(PRT-062070; PRT2070) is an novel oral dual Syk/JAK inhibitor.
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DC9765 CERC-501(LY-2456302,Aticaprant) Featured
CERC-501(LY-2456302) is a potent, selective antagonist of the kappa opioid receptor (KOR) (Ki = 0.81 nM vs. 24.0 nM and 155 nM for the μ-opioid receptor (MOR) and δ-opioid receptor (DOR), respectively.
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DC10337 CEP-40783 Featured
CEP-40783 is a potent, selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively.
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DC11078 Cenupatide Featured
Cenupatide is an urokinase plasminogen activator receptor (uPAR) inhibitor drug candidate. Cenupatide inhibits uPAR binding to the formyl peptide receptors (FPRs) can improve kidney lesions in a rat model of streptozotocin (STZ)-induced diabetes. Cenupati
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DC32353 Cenicriviroc Mesylate Featured
Cenicriviroc, also known as TAK-652 and TBR-652, is an experimental drug candidate for the treatment of HIV infection. It is being developed by Takeda Pharmaceutical and Tobira Therapeutics. Cenicriviroc is an inhibitor of CCR2 and CCR5 receptors, allowi
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