Sarafotoxin S6a, a sarafotoxin analogue, is a endothelin receptor agonist and has an ETA/ETB selectivity profile similar to that of Endothelin-3. Sarafotoxin S6a elicits the pig coronary artery with an EC50 value of 7.5 nM.

Homobaldrinal is a decomposition product of Valepotriate. Homobaldrinal exhibits genotoxic activity in the Salmonella/microsome test.

Cortisol sulfate sodium (Cortisol 21-sulfate) is a metabolite of Cortisol. Cortisol sulfate sodium is a specific ligand for intracellular transcortin.

Necroptosis-IN-1, an analog of Necrostatin-1, is a potent necroptosi inhibitor. Necroptosis-IN-1 is a RIPK inhibitor.

Proguanil hydrochloride, an antimalarial prodrug, is metabolized to the active metabolite Cycloguanil. Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor.

Cortisol sulfate (Cortisol 21-sulfate) is a metabolite of Cortisol. Cortisol sulfate is a specific ligand for intracellular transcortin.

Sulfadiazine-13C6 is a labeled Sulfadiazine. Sulfadiazine is a sulfonamide antibiotic with antimalarial activity.

(E/Z)-AG490 ((E/Z)-Tyrphostin AG490) is a racemic compound of (E)-AG490 and (Z)-AG490 isomers. (E)-AG490 is a tyrosine kinase inhibitor that inhibits EGFR, Stat-3 and JAK2/3.

Vat Blue 2, a indigo derivative, is a dark blue 5,5'-dibromo-4,4'-dichloroindigo dye.

5-HT1A modulator 2 hydrochloride, a derivative of 8-OH-DPAT, is a modulator of 5-HT1A with a Ki of 53 nM for 5-HT1A binding.

N-Desmethyl imatinib mesylate (Norimatinib mesylate) is a metabolite of Imatinib. Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR.

Rafoxanide 13C6 is a labeled Rafoxanide. Rafoxanide is a salicylanilide used as an antiparasitic agent.

5'-Fluoroindirubinoxime (5’-FIO, compound 13), an Indirubin derivative, is a potent FLT3 inhibitor, with an IC50 of 15 nM.

Phenylacetic acid mustard is the major metabolite of the cancer chemotherapeutic agent Chlorambucil. Chlorambucil is an alkylating agent with antitumor activity.

Desoxycarbadox is a metabolite of Carbadox. Carbadox is a quinoxaline-di-N-oxide antibiotic compound.

Resolvin D1 methyl ester (RvD1 methyl ester) is the methyl ester of Resolvin D1. Resolvin D1 methyl ester reduces triglyceride levels.

Nordoxepin D3 hydrochloride (Desmethyldoxepin D3 hydrochloride) is the deuterium labeled Nordoxepin hydrochloride. Nordoxepin hydrochloride is an active metabolite of Doxepin hydrochloride, which is an orally active tricyclic antidepressant.

CLK-IN-T3N, the negative control of CLK-IN-T3, is a chemical probe for CDC-like kinase (CLK).

FM-479 is the negative control of FM-381 and has no activity on JAK3 or other kinases.

O-Desmethyl PKC412-d5 (CGP62221-d5) is a deuterium labeled O-Desmethyl PKC412. O-Desmethyl Midostaurin (CGP62221; O-Desmethyl PKC412) is the active metabolite of Midostaurin via cytochrome P450 liver enzyme metabolism.

Loperamide phenyl is an impurity of Loperamide. Loperamide is an opioid receptor agonist.

Z-VDVA-(DL-Asp)-FMK is a Z-VDVAD-FMK derivative. Z-VDVAD-FMK is a special inhibitor of caspase-2.

QX-222 chloride, a trimethyl analogue of Lignocaine, is a potent Na+ channel blocker.

SAG dihydrochloride is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM). SAG dihydrochloride activates the Hedgehog signaling pathway and counteracts Cyclopamine inhibition of Smo.

Strictosidine, the central intermediate in monoterpene indole alkaloid (MIA) biosynthesis, undergoes a series of reactions to produce over 3,000 known MIAs such as Vincristine, Quinine, and Strychnine.

ABM-14 is a ligand for targeting androgen receptor (AR) for PROTAC. ABM-14 binds to a ligand for VHL via linker to form ARCC-4 to degrade AR。

Melanin probe-2 (compound 5) is a non-radioactive bromopicolinamide precursor. Melanin probe-2 can be used for 18F-Labeled Picolinamide PET probe synthesis.

Desmorpholinyl Navitoclax-NH-Me is a Bcl-xL inhibitor. Desmorpholinyl Navitoclax-NH-Me and a CRBN ligand for the E3 ubiquitin ligase can be used in the synthesis of PROTAC BCL-XL degrader XZ739.

Apcin-A, an Apcin derivative, is an anaphase-promoting complex (APC). Apcin-A interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A can be used to synthesize the PROTAC CP5V.

ELA RR>GG (ELA-32 negative control), an ELABELA (ELA-32 human) mutant peptide, is inactive. ELA RR>GG is a negative control for ELABELA.