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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DC49397 Epicoccone B
Epicoccone B, firstly reported from C. globosum, exhibits the DPPH free radical scavenging ability with IC50 value of 10.8 μM, and has potent α-glucosidase inhibition with IC50 value of 27.3 μM. Anti-HIV activity.
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DC49396 Flavipin
Flavipin is an aryl hydrocarbon receptor (Ahr) agonist that induces the expression of Ahr downstream genes in mouse CD4+ T cells and CD11b+ macrophages. Flavipin inhibits the stabilizing function of Arid5a on Il23a 3′UTR, a newly identified target mRNA. Flavipin exhibits the DPPH free radical scavenging ability with IC50 value of 7.2 μM, and has potent α-glucosidase inhibition with IC50 value of 33.8 μM.
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DC49395 Phenosulfazole
Phenosulfazole is an effective antiviral agent. Phenosulfazole has the potential for the research of poliomyelitis virus.
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DC49394 5-Amino-8-hydroxyquinoline
5-Amino-8-hydroxyquinoline (5A8HQ), a potential anticancer candidate, has promising proteasome inhibitory activity.
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DC49393 3,5,7-Trihydroxychromone
3,5,7-Trihydroxychromone is the analogue of galangin. 3,5,7-Trihydroxychromone is also the binder of bovine serum albumin. 3,5,7-Trihydroxychromone undergoes multiple antioxidant pathways.
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DC49392 (±)-Muscarine chloride
(±)-Muscarine chloride is the racemate of Muscarine chloride. Muscarine is a prototype muscarinic acetylcholine receptor agonist.
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DC49391 D-Isofloridoside
D-Isofloridoside, one of the polysaccharide precursors, has the activity of scavenging free radicals, inhibiting ROS expression, and inhibiting MMP-2 and MMP-9.
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DC49390 PLGA-PEG-NH2
PLGA-PEG-NH2 is a material to synthesis nanomicelles. PLGA-PEG-NH2 nanomicelle is an efficient delivery system of Irinotecan for targeted colorectal cancer and hepatocellular carcinoma.
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DC49389 α-HNJNAc
α-HNJNAc is a potent, competitive hexosaminidases inhibitor without interfering with other glycosidases.
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DC49386 2-Amino-8-oxononanoic acid
2-Amino-8-oxononanoic acid is an amino acid, incorporation into proteins in E.coli in genetic. 2-Amino-8-oxononanoic acid is efficient in labeling of proteins with different probes with a site-specific manner under a mild condition close to the physiological pH.
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DC49384 Piperidione
Piperidione is a cough sedative.
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DC49383 Pheniprazine
Pheniprazine is a potent and long acting inhibitor of monoamine oxidase. Pheniprazine has the potential for the research of depression.
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DC49382 Gepefrine
Gepefrine is an orally active pressor agent and sympathomimetic agent. Gepefrine improves the early orthostatic disregulation of the arterial pressure.
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DC49381 1-Phenyl-1-propanol
1-Phenyl-1-propanol is used as a chiral building block and synthetic intermediate in the pharmaceutical industries. 1-Phenyl-1-propanol is an intermediate of anti-depressant drug Fluoxetine.
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DC49380 L-Tyrosine-17O
L-Tyrosine-17O is the 17O-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
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DC49379 8-Azanebularine
8-Azanebularine, a compound with hydrogen in place of the C6 amino group, inhibits the ADAR2 reaction at high concentrations (IC50=15 mM). 8-Azanebularine is incorporated into an RNA structure recognized by human ADAR2 results in high-affinity binding (KD=2 nM). 8-Azanebularine can be used for the research of ADAR-catalyzed RNA-editing reaction.
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DC49378 rel-Tranylcypromine
rel-Tranylcypromine (SKF 385) is a potent monoamine oxidase (MAO) inhibitor.
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DC49377 RMC-4627
RMC-4627 is a selective mTORC1 inhibitor that activates 4EBP1 and inhibits tumor growth.
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DC49376 2-(4-Chlorophenoxy)ethanol
2-(4-Chlorophenoxy)ethanol is used as an intermediate (such as for herbicides).
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DC49375 Glycerylphosphorylcholine
Glycerylphosphorylcholine is a precursor of free choline in mammalian semen.
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DC49374 Bis-Tris
Bis-Tris is a commonly used buffer.
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DC49371 Cyclo(D-Ala-L-Pro)
Cyclo(D-Ala-L-Pro) is a cyclodipeptide.
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DC49370 4-(Dimethylamino)phenol
4-(Dimethylamino)phenol increases the extracellular lactate dehydrogenase (LDH) without markedly affecting gluconeogenesis. 4-(Dimethylamino)phenol cannot decreases the ATP content until the membrane becomes permeable to LDH.
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DC49369 Endothall
Endothall (Endothal) is a protein phosphatase 2A (PP2A) inhibitor with IC50s of 90 nM and 5 µM for PP2A and PP1, respectively. Endothall can be used as an herbicide. Endothall also is useful in cancer chemotherapy.
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DC49368 2,6-Dimethoxyphenol
2,6-Dimethoxyphenol is a phenolic compound that is extensively used for the measurement of laccase activity.
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DC49367 (S)-1-(4-Hydroxyphenyl)ethane-1,2-diol
(S)-1-(4-Hydroxyphenyl)ethane-1,2-diol is an active constituent of the aerial parts of Angelica sinensis. (S)-1-(4-Hydroxyphenyl)ethane-1,2-diol significantly inhibits the growth of Aeromonas hydrophila. Anticoagulative and antibiotic activities.
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DC49366 Heterobivalent ligand-1
Heterobivalent ligand-1 (compound 26) is a heterobivalent ligand for the Adenosine A 2A-dopamine D 2 receptor heteromer (KDB1 A2AR=2.1 nM, KDB1 D2R= 0.13 nM).
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DC49365 Zendusortide
Zendusortide is a sortilin binding peptide.
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DC49363 L-Tyrosine-4-13C
L-Tyrosine-4-13C is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
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DC49362 L-Tyrosine-1-13C
L-Tyrosine-1-13C is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
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