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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DC28934 VAF347 Featured
VAF347 is a cell permeable and highly affinity aryl hydrocarbon receptor (AhR) agonist and induces AhR signaling. VAF347 inhibits the development of CD14+CD11b+ monocytes from granulo-monocytic (GM stage) precursors. VAF347 has anti-inflammatory effects.
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DC12044 CA-5f Featured
CA-5f is a novel late-stage autophagy inhibitor with potent anti-tumor effect against non-small cell lung cancer.
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DC10736 CaCC(inh)-A01 Featured
CaCC(inh)-A01 is a non-selective inhibitor of calcium-activated chloride channels (CaCCs) that blocks ATP-stimulated chloride conductance in human salivary gland, intestinal, and bronchial epithelium (mean IC50 = 10 µM).
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DC10457 Cadazolid (ACT-179811) Featured
Cadazolid (ACT-179811) is a novel fluoroquinolone-oxazolidinone antibiotic and a protein synthesis inhibitor.
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DC10327 Calcitonin salmon Featured
Calcitonin, Salmon is a calcium regulating hormone secreted from mammalian thyroid parafollicular cells and in non-mammalian species from the ultimobranchial gland.
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DC7967 calpeptin Featured
calpeptin is Ca2+-dependent protease,calpain inhibitor
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DC10744 Cambinol Featured
Cambinol is a SIRT1 and SIRT2 inhibitor with IC50 values of 56 and 59 μM, respectively.
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DC20512 VHL ligand 1 Featured
PROTAC-VHL-ligand is a von Hippel–Lindau (VHL) ligand used for the proteolysis targeting chimeras (PROTACs) method, induces target protein degradation..
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DC8456 Cardiogenol C (hydrochloride) Featured
Cardiogenol C is a diaminopyrimidine that induces cardiomyogenesis in mouse embryonic stem cells.
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DC10847 CAY10441(RO1138452) Featured
CAY10441 is a Selective prostacyclin IP receptor antagonist.
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DC10903 CAY10465 Featured
CAY10465 is an analog of resveratrol acting as a potent and selective aryl hydrocarbon receptor agonist, with a Ki of 0.2 nM.
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DC10579 CAY 10602 Featured
CAY10602 is a SIRT1 activator.
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DC4160 CB-03-01 Featured
CB-03-01 is a steroidal ester, androgen antagonist derived from 11-deoxycortisone, which tightly mimics the profile of an ideal anti-androgen for topical use.
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DC10449 CB7921220 Featured
CB7921220 is an inhibitor of Adenylyl Cyclase isoform-1 (AC1) and isoform-6 (AC6).
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DC8497 CC-223 Featured
CC-223 is a potent mTOR kinase inhibitor (IC50=16 nM), with >150-fold sensitivity over the related lipid kinase PI3Kα (IC50=4 μM).
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DC7096 CC-401 Featured
CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity.
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DC11302 CCG215022 Featured
CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15±0.07 μM, 0.38±0.06 μM and 3.9±1 μM for GRK2, GRK5 and GRK1, respectively.
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DC10005 CCT196969 Featured
CCT196969 is a novel orally available, pan-RAF inhibitor with anti-SRC activity.
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DC8324 CCT244747 Featured
CCT244747 represents the first structural disclosure of a highly selective, orally active CHK1 inhibitor and warrants further evaluation alone or combined with genotoxic anticancer therapies.
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DC10909 BN82002 Featured
CDC25 Phosphatase Inhibitor I, BN82002, is a cell-permeable ortho-hydroxybenzylamino compound that has been reported to display antitumor properties.
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DC12026 CDDO-2P-Imidazolide Featured
CDDO-2P-Im is a new analogue of CDDO-Imidazolid,showing better bioactive than CDDO-Imidazolid.
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DC12027 CDDO-3P-Imidazolide Featured
CDDO-3P-Im is a new analogue of CDDO-Imidazolid,showing better bioactive than CDDO-Imidazolid.
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DC12025 CDDO imidazolide Featured
CDDO-imidazolide is a potent inducer of heme oxygenase-1 and Nrf2/ARE signaling,with potent antiproliferative, differentiating, and anti-inflammatory activities.
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DC9277 C-DIM12 Featured
C-DIM12 is a novel synthetic activator of Nurr1.
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DC20334 CDK2 inhibitor 73 Featured
CDK2 inhibitor 73 is a potent, selective CDK2 inhibitor with IC50 of 44 nM for CDK2/cyclin A, displays 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM)..
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DC48426 Rafutrombopag
Rafutrombopag is a thrombopoietin (TPO) agonist extracted from patent CN113929668 A.
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DC48425 TGFβR-IN-1
TGFβR-IN-1 is a long-acting tumor-activated prodrug of a TGFβR inhibitor.
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DC48422 6-Bnz-cAMP sodium salt
6-Bnz-cAMP sodium salt is a cell-permeable cAMP analog. 6-Bnz-cAMP selectively activates cAMP-dependent PKA but not Epac signaling pathways.
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DC48421 SHP2 protein degrader-1
SHP2 protein degrader-1 is a potent allosteric inhibitor of SHP2. SHP2 protein degrader-1 induces SHP2 degradation and cell apoptosis. SHP2 protein degrader-1 has the potential for the treatment of SHP2 related diseases.
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DC48420 Orexin B, rat, mouse TFA
Orexin B, rat, mouse (Rat orexin B) TFA is an endogenous orexin receptor agonist. Orexin B, rat, mouse TFA binds and activates two closely related orphan G protein-coupled receptors OX1-R and OX2-R. Orexin B, rat, mouse TFA stimulates food intake and energy expenditure and plays a significant role in sleep-wakefulness regulation.
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