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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DC44742 SB-203186 hydrochloride
SB-203186 hydrochloride is a potent and competitive 5-HT4 antagonist. SB-203186 hydrochloride antagonizes the 5-HT4 receptor-mediated relaxations of the carbachol-contracted rat isolated oesophagus against 5-HT with pKB values of 10.9 (rat oesophagus), 9.
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DC44741 Poriol
Poriol is a flavonoid isolated from Pseudotsuga sinensis.
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DC44740 Allylestrenol
Allylestrenol is an orally active progestagen of the 19-nortestosterone series resembling progesterone.
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DC44739 Ponceau S
Ponceau S (Acid Red 112) is the most commonly used stain for immunoblotting protocols. Ponceau S dye is applied as an acidic aqueous solution, and the proteins on the membrane are stained with red color.
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DC44738 Oil Red O
Oil red O (ORO) is a commonly used dye for the tissue staining, which recognizes nitroglycerin and cholesterol esters. Oil red O can be fluorescently lighted up upon meeting dsDNA with emission peak localized at 600 nm, although it almost does not fluores
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DC44737 PNPP
PNPP (p-nitrophenyl phosphonate) is a substrate for alkaline and acid phosphatases used in enzyme-linked immunoassay (ELISA) and conventional spectrophotometric assays.
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DC44736 1,3-Diphenylisobenzofuran
1,3-Diphenylisobenzofuran (DPBF) is a fluorescent probe which possesses a highly specific reactivity towards singlet oxygen (1O2) forming an endoperoxide which decomposes to give 1,2-dibenzoylbenzene. 1,3-Diphenylisobenzofuran can detect the generation of
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DC44735 NEP
NEP (VDP-green (NEP)) is a turn-on fluorescent probe based on the intramolecular charge transfer (ICT) mechanism for sensing vicinal dithiol-containing proteins (VDPs). NEP is exhibits high selectivity toward VDPs in live cells and in vivo and displays a
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DC44734 EtS-DMAB
EtS-DMAB (HClO-green) is a fluorescent probe, which can selectively detect hypochlorous acid (HOCl) (λex=440 nm, λem=610 nm). EtS-DMAB is applied to image exogenous and endogenous HOCl in live cells.
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DC44733 Fast-TRFS
Fast-TRFS is a selective and superfast fluorogenic probe of thioredoxin reductase (TrxR). Fast-TRFS can be used for imaging TrxR activity in live cells.
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DC44732 BODIPY-TS
BODIPY-TS (Thiol-green 2) is a fast response and thiol-specific turn-on probe. BODIPY-TS utilizes the thiosulfonate scaffold as a thiol recognition unit. BODIPY-TS has low toxicity, and features high selectivity, low detection limit, and quantitative reac
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DC44731 EDANS
EDANS (1,5-EDANS) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET).
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DC44730 Acrylodan
Acrylodan, reacted with thiols, is sensitive to the local environmental dipolarity and dynamics within the binding pocket surrounding Cys34.
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DC44729 Sel-green
Sel-green, a selective selenol fluorescent probe, is applied to quantify the Sec content in the selenoenzyme thioredoxin reductase and image endogenous Sec in live HepG2 cells.
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DC44728 Mito-TRFS
Mito-TRFS, the first off-on probe, is used to image the mitochondrial thioredoxin reductase (TrxR2) in live cells.
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DC44727 Seph-PAO
Seph-PAO is the modified PAO attached a sepharose fluorophore and is used to detect the thioredoxin reductase (TrxR).
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DC44725 13,21-Dihydroeurycomanone
13,21-Dihydroeurycomanone, a natural compound isolated from Eurycoma longifolia root, possesses anti-parasite activity for Plasmodium falciparum and Toxoplasma gondii.
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DC44724 Cyanidin 3-sambubioside chloride
Cyanidin 3-sambubioside chloride (Cyanidin-3-O-sambubioside chloride), a major anthocyanin, a natural colorant, and is a potent NO inhibitor. Cyanidin 3-sambubioside chloride is a H274Y mutation inhibitor, and inhibits influenza neuraminidase activity wit
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DC44723 2'-Deoxy-2'-fluorocytidine
2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency of both compounds antiviral effects
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DC44721 Antifungal agent 6
Antifungal agent 6 is an antifungal agent.
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DC44720 Neocnidilide
Neocnidilide is an alkylphthalide, which has the activity of inhibiting the growth of mycotoxin-producing fungi. Neocnidilide also has larvicidal activity against D. melanogaster with a LC50 value of 9.9 μmol/mL.
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DC44719 3,5-Di-tert-butylphenol
3,5-Di-tert-butylphenol is an volatile organic compound with anti-biofilm and antifungal activities. 3,5-Di-tert-butylphenol induces accumulation of reactive oxygen species (ROS).
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DC44718 Tunicamycin V
Tunicamycin V (Tunicamycin A) is a nucleoside natural product that inhibits bacterial phospho-N-acetylmuramyl-pentapeptide transferase (MraY) with an IC50 of 0.35 μM. Tunicamycin V has antibacterial activties.
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DC44717 Diethyl butylmalonate
Diethyl butylmalonate exhibits toxicity to T. pyriformis, with a log(IGC50-1) of 0.557.
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DC44716 Hexahydrofarnesyl acetone
Hexahydrofarnesyl acetone (6,10,14-Trimethyl-2-pentadecanone), a sesquiterpene isolated from Launaea mucronata, is the major constituents of the essential oil. Hexahydrofarnesyl acetone has antibacterial, anti-nociceptive and anti-inflammation activities.
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DC44715 8-Br-GTP
8-Br-GTP, a GTP analog, is a competitive FtsZ polymerization and GTPase activity (Ki of 31.8 μM) inhibitor. 8-Br-GTP can be used for nucleic acid modification.
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DC44714 Procaine penicillin G
Penicillin G Procaine (PGP, Penicillin G Procaine, Bicillin C-R), a crystalline complex combining penicillin G with procaine, is a β-lactam antibiotic.
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DC44713 Cefpiramide
Cefpiramide (Cefpiramide acid, Cefpiramido, Cefpiramidum, WY-44635, SM-1652) is a pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity.
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DC44706 Metformin
Metformin (1,1-Dimethylbiguanide), a widely used drug for treatment of type 2 diabetes, activates AMP-activated protein kinase (AMPK) in hepatocytes. Metformin promotes mitophagy in mononuclear cells. Metformin induces apoptosis of lung cancer cells throu
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DC44705 3-Hydroxy-2-methylpyridine
3-Hydroxy-2-methylpyridine, isolated from alkaline extracts of cocoa, is used in the synthesis of pyrimidine.
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