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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DC42175 Prion Protein 106-126 (human)
Prion Protein 106-126 (human), a peptide fragment of prion, and can induct neuronal apoptosis, antiproteinase K digestion, fiber formation, and mediate the conversion of normal cellular prion protein (PrPc) into pathogenic isoform (PrPSc). Prion Protein 106-126 (human) is generally used as the model to investigate neural degeneration of prion disease.
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DC42174 4-Hydroxybenzyl cyanide
4-Hydroxybenzyl cyanide is an endogenous metabolite.
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DC42173 4-Ethoxyphenol
4-Ethoxyphenol is an endogenous metabolite.
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DC42172 1,4-Dimethoxybenzene
1,4-Dimethoxybenzene is an endogenous metabolite.
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DC42171 2',4'-Dimethylacetophenone
2',4'-Dimethylacetophenone is an endogenous metabolite.
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DC42170 Acetylvaline
Acetylvaline is an endogenous metabolite.
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DC42169 β-Ionone
β-Ionone, isolated from plant oils, is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity.
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DC42168 Anabasine hydrochloride
Anabasine ((S)-Anabasine) hydrochloride is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical?pesticide?nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM).
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DC42167 BPBA
BPBA (2-Bromopyridine-5-boronic acid) is a new labeling reagent to derivatize brassinosteroids (BRs).
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DC42166 2-Naphthoxyacetic acid
2-Naphthoxyacetic acid is an endogenous metabolite.
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DC42165 Metamitron
Metamitron is a pre- and post-emergence herbicide used for the control of broad-leaved weeds and grasses in sugar beet.
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DC42164 2,4-Di-tert-butylphenol
2,4-Di-tert-butylphenol is an endogenous metabolite.
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DC42163 Dichlormid
Dichlormid is a herbicide safener. Dichlormid up-regulates expression of ZmGST27 and ZmMRP1 and increases ZmGT1.
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DC42162 AP-18
AP-18, a potent and selective TRPA1 inhibitor, blocks activation of TRPA1 by 50 μM Cinnamaldehyde with an IC50 of 3.1 μM and 4.5 μM for human and mouse TRPA1, respectively. AP-18 reverses complete Freund's adjuvant (CFA)-induced mechanical hyperalgesia in mice. AP-18 attenuated 30 μM AITC-induced Yo-Pro uptake in a concentration-dependent manner, with an IC50 of 10.3 μM.
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DC42161 3-Phenoxybenzoic acid
3-Phenoxybenzoic acid is an endogenous metabolite.
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DC42160 7-Aminodeacetoxycephalosporanic acid
7-Aminodeacetoxycephalosporanic acid (7-ADCA) is a key intermediate in the synthesis of cephalosporins.
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DC42159 4-(3-Methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid
4-(3-Methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid has hypoglycaemic activity. 4-(3-Methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid follows a mechanism based on the response to the oral glucose overcharge.
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DC42158 2-Palmitoylglycerol
2-Palmitoylglycerol (2-Palm-Gl), an congener of 2-arachidonoylglycerol (2-AG), is a modest cannabinoid receptor CB1 agonist. 2-Palmitoylglycerol also may be an endogenous ligand for GPR119.
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DC42157 Thiodicarb
Thiodicarb is a carbamate insecticide used to control flies in animal and poultry houses and dairies. Thiodicarb is metabolized into methomyl in animals and plants, and subsequently degraded into carbon dioxide and acetonitrile.
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DC42156 Chlorhexidine diacetate
Chlorhexidine diacetate is a biguanide disinfectant with rapid bactericidal activity against both Gram-positive and Gram-negative organism. The antibacterial effect of chlorhexidine diacetate is related to its action on the bacterial cell membrane and to precipitation of intracellular contents.
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DC42155 6-Aminopenicillanic acid
6-Aminopenicillanic acid (6-APA) is an important precursor for the synthesis of ?-lactam antibiotics. 6-Aminopenicillanic acid is the main product of Penicillin G (PenG) hydrolyzed by penicillin acylase (PA).
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DC42152 3-Methyl-2-cyclopenten-1-one
3-Methyl-2-cyclopenten-1-one is an endogenous metabolite.
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DC42150 2-Thiophenecarboxaldehyde
2-Thiophenecarboxaldehyde is an endogenous metabolite.
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DC42149 D-Threonine
D-Threonine (H-D-Thr-OH) is an enantiomer of L-threonine. D-Threonine is a metabolite of Saccharomyces cerevisiae.
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DC42148 p-Tolualdehyde
p-Tolualdehyde is an endogenous metabolite.
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DC42147 4-Methylanisole
4-Methylanisole (4-Methoxytoluene) is food flavoring agent and can be naturally found in Ylang Ylang fragrance oil.
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DC42146 Isoquinoline
Isoquinoline is an analog of?pyridine. Isoquinoline structural-based alkaloids, such as tropoloisoquinoline, phthalideisoquinoline, and naphthylisoquinoline has anti-cancer activities.
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DC42145 2-Methylacetophenone
2-Methylacetophenone is an endogenous metabolite.
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DC42144 4-Ethylbenzaldehyde
4-Ethylbenzaldehyde is an endogenous metabolite.
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DC42143 1,5,5-Trimethylhydantoin
1,5,5-Trimethylhydantoin (TMH) is a non-isotopic internal standard (IS).
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