GLPG-0259 is a small-molecule inhibitor of mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), a kinase enzyme that plays a role in important inflammatory pathways.

Fasnall is a selective FASN inhibitor that acts through its co-factor binding sites. Fasnall also shows potent anti-tumor activity in the MMTV-Neu model of HER2(+) breast cancer, particularly when combined with carboplatin.

UCL2077 is a selective slow-afterhyperpolarization (sAHP) channel blocker. UCL2077 suppresses the sAHP present in hippocampal neurons in culture and in the slice preparation. UCL2077 is selective and has minimal effects on Ca(2+) channels, action potentials, input resistance and the medium afterhyperpolarization.

Inz-1 is a fungal-selective inhibitor of mitochondrial cytochrome bc1.

RBI-257 Maleate is a highly potent dopamine D4 receptor-selective ligand. RBI-257 Maleate may be a useful probe or radioligand for brain dopamine D4 receptors.

ISAM-140 is a potent and highly selective A2B adenosine receptor antagonist.

Coumarin 343 is a blue emitting fluorophore used as a laser dye. The fluorophore can serve as a FRET donor for FAM (fluorescein).

TAMRA alkyne for Click chemistry, pure 5-isomer. TAMRA (TMR, tetramethylrhodamine) is a xanthene dye. It forms a FRET pair with fluorescein. This alkyne is suitable for Copper-catalyzed Click chemistry (CuAAC).

Blue emitting Coumarin 343 dye can form a FRET pair with fluorescein (FAM). An amine reactive form, activated NHS ester. This amine-reactive NHS ester contains an aminohexanoyl linker between the fluorophore, and the reactive group. This linker provides better solubility and spatial separation between the fluorophore, and the target molecule being labeled.

2-Iodobenzoic acid is an organic compound and the impact-sensitive intermediate in the synthesis of the Dess-Martin periodinane.

Mecoprop is an herbicide and used to control broadleaf weeds.

2-Acetylnaphthalene is an anticonvulsant/antimicrobial and a fragrance agent. It has a sulfurous type odor and an onion type flavor.

Phenyl ethyl ketone is an aryl ketone. It is a colorless, sweet-smelling liquid that is insoluble in water, but miscible with organic solvents. It is used in the preparation of other compounds.

NCT-14b is a selective HDAC6 inhibitor. It inhibits cell growth of α-positive MCF-7 breast cancer cells treated with estrogen but not untreated cells.

Risocaine is a local anesthetic.

Bensulfuron-methyl is a herbicide.

Lithium guanosine triphosphate functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.

Dienestrol diacetate is a derivative of the synthetic non-steroid phenolic compound, DIENESTROL, which exhibits estrogenic activities.

Ligustilide A is an active ingredient isolated from the medicinal plants Cnidium officinale and Angelica acutiloba. Ligustilide A inhibits benzo(a)pyrene-induced CYP1A1 upregulation in cultured human keratinocytes via ROS-dependent Nrf2 activation.

Cinnamtannin B1 is an A-type proanthocyanidin contained in several plant species such as Laurus nobilis L., Vaccinium vitis-idaea, Parameria laevigata, Cinnamomum zeylanicum and Lindera umbellata. Cinnamtannin B-1 is a potent antioxidant and protective agent against oxidative stress and apoptosis in human platelets. Cinnamtannin B-1 is a Cox-2 (cyclooxygenase-2) inhibitor.

Lapachol has antimicrobial properties against many pathogens. It has anti-inflammatory, analgesic and antibiotic properties. It is inhibitor of epithelial tumors in Drosophila melanogaster heterozygote.

N(G)-Nitroarginine-4-nitroanilide is an anti-nociceptive agent in the mouse.

Neurokinin K is a mammalian neuropeptide of 10 amino acids that belongs to the tachykinin family. It is similar in structure and action to SUBSTANCE P and NEUROKININ A with the ability to excite neurons, dilate blood vessels, and contract smooth muscles, such as those in the URINARY BLADDER and UTERUS.

Neurokinin A is a mammalian neuropeptide of 10 amino acids that belongs to the tachykinin family. It is similar in structure and action to SUBSTANCE P and NEUROKININ B with the ability to excite neurons, dilate blood vessels, and contract smooth muscles, such as those in the BRONCHI.

L-6355 is a bioactive chemical.

Sorbose is a ketose sugar that is commonly used in the commercial synthesis of ASCORBIC ACID.

L-Serine-1-13C is an amino acid.

Tartaric acid is a white crystalline organic acid that occurs naturally in many fruits, most notably in grapes, but also in bananas, tamarinds and citrus[4]. Its salt, potassium bitartrate, commonly known as cream of tartar, develops naturally in the process of winemaking. It is commonly mixed with sodium bicarbonate and is sold as baking powder used as a leavening agent in food preparation. The acid itself is added to foods as an antioxidant and to impart its distinctive sour taste. Tartaric is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics, and is a dihydroxyl derivative of succinic acid.

JWH 249 is a synthetic cannabinoid (CB) that potently activates the central CB1 and peripheral CB2 receptors (Ki = 8.4 and 20 nM, respectively).

JWH 167 is a synthetic cannabinoid (CB) with moderate affinities for both central CB1 (Ki = 90 nM) and peripheral CB2 (Ki = 159 nM) receptors. Its physiological and toxicological properties are not known. This product is intended for forensic and research purposes.