mGluR

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Cat. No.	Product Name	Field of Application
DC11121	VU0418506	VU0418506 (VU 0418506) is a potent and selective mGlu4 positive allosteric modulator (PAM) with EC50 of 68 nM (hmGlu4). More description
DC9074	Topiramate	Topiramate is an anticonvulsant that antagonizes GluR5 receptors and acts as a positive allosteric modulator of GABA receptor-mediated currents. More description
DC9507	MTEP (hydrochloride)	MTEP Hcl is a potent, selective and non-competitive mGlu5 antagonist with IC50 and Ki of 5 nM and 16 nM, respectively. More description
DC11323	LY354740	LY354740 is an agonist of the group II metabotropic glutamate receptor (mGluR) subtypes mGluR2 and mGluR3 (Kis = 99 and 94 nM, respectively). More description
DC9937	BMT-145027	BMT-145027 is a potent mGluR5 PAM with no inherent mGluR5 agonist activity. More description
DC11894	Foliglurax	A potent, selective, brain-penetrant and orally bioavailable mGluR4 positive allosteric modulator with EC50 of 79 nM. More description
DC11895	Foliglurax hydrochloride	A potent, selective, brain-penetrant and orally bioavailable mGluR4 positive allosteric modulator with EC50 of 79 nM. More description
DC11609	VU6010608	A potent, highly selective, CNS penetrant mGlu7 negative allosteric modulator with IC50 of 0.76 uM. More description
DC10160	(1R,2S)-VU0155041	(1R,2S)-VU0155041, Cis regioisomer of VU0155041, is a partial mGluR4 agonist with an EC50 of 2.35 μM. More description