Highly selective, extremely potent Mps1 kinase inhibitor

Novel Entry Inhibitor of both CCR5- and CXCR4-Tropic Strains of Human Immunodeficiency Virus Type 1 (HIV-1), Targeting a Novel Site on gp41

Novel potent and selective inhibitor of the activation-loop mutant Kit phosphorylation and tumor growth

Potent, ATP-competitive, reversible inhibitor of FAK

Antimalarial, actively against Plasmodium liver stages

Selective and potent PDK1 inhibitor inducing anti-tumor activity in breast cancer cells

Potent and selective 5-HT2C receptor agonist

Highly selective, extremely potent Mps1 kinase inhibitor

Novel dual H3/4 histamine receptor antagonist

Potent, selective non-peptidic antagonist of the V1a receptor

Natural cyclic tetrapeptide HDAC Inhibitor through the inhibition of PfHDAC1 catalytic activity, potently inducing the synthesis of metallothionein

Novel SAM Competitive PRMT5 Inhibitor, Demonstrating Antitumor Activity in Splicing Dysregulated NSCLC with Decreased Liability of Drug Resistance

Novel prdrug of PF-06843195, a potent PI3Kα-selective inhibitor

Novel potent and selective inhibitor of MAP4K4

Novel tyrosine residues probe, rationally targeting active site

Novel potent and selective inhibitor of MAP4K4

Novel non-brain-penetrant long-acting peptide oxytocin (OT) receptor agonist with increased selectivity for the OT receptor and significantly increased pharmacokinetic stability

Novel potent and highly selective leucine rich repeat kinase 2 (LRRK2) inhibitor

Novel potent TRPV4 antagonist (hTRPV4 IC50 4nM; rTRPV4 IC50 27nM)

Novel selective hTRPV4 Antagonist (hTRPV4 IC50 49nM; rTRPV4 IC50 1,150nM)

Irriversible inhibitor of kynurenine amino transferase II (KAT II)

Novel potent and selective PDE8B/8A inhibitor

Selective dopamine D3/D2 receptor antagonist

Dose dependent inhibitor of multiple fibrotic genes

Novel γ-secretase inhibitor

Novel allosteric inhibitor of E. coli Hsp70 (DnaK) and human Hsp70 proteins

Non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor

Exceptionally Potent and Membrane-Embedded Inhibitor of Bilayer Lipid Peroxidation

Agonist of dopamine receptor subtypes D1 and D2

Broad-spectrum virus- and host-targeting peptide, inhibiting coronaviruses and other respiratory viruses