Novel cell permeable caged Luciferin

Novel potent and selective PROTAC degrader of myeloid cell leukemia 1 (MCL1)

Novel non-nucleoside inhibitor of Zika viral RNA-dependent RNA polymerase (RdRp) enzymes

Novel blocker of the TLR2 and TLR4 downstream signaling pathway, effectively inhibiting mRNA expression of MyD88 and p65, major subunit of nuclear factor-kappaB

Novel antineoplastic agent, exhibiting remarkable anticancer activity as well as excellent cellular selectivity

Novel multi-target anticancer prodrug activated by the tumor specific CYP1B1 enzyme, potently inhibiting HCT-15, HCT-116 and K562 cells growth, showing moderate anti-proliferative activity towards MDA-MB-231, HepG2, PANC, Bel7402 and MGC803 cancer cells,

Prodrug of CPPTL, inducing apoptosis in a dose-dependent manner via the ROS/JNK pathway in acute myeloid leukemia

Chromogenic peptide substrate, being highly sensitive for the measurement of activated Protein C.

Ultrasensitive bioluminogenic enzyme substrate

Competitive inhibitor of both SPHK1 and SPHK2

Specific protein disorder catalyzer of HIV-1 Nef

Novel potent anti-MRSA agent, disrupting biofilms with no resistance development, sensitizing rifampicin and tetracycline against multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa

Novel acetylcholinesterase inhibitor, promoting synaptic function and neuronal survival, ameliorating cognitive deficits in SAMP8 mice via improved mitochondrial dynamics and increased activity of the NMDAR-CREB-BDNF pathway

Novel autophagonizer, inducing autophagic cell death in apoptosis-defective cell line

Inhibitor of NF-kappaB-mediated GROalpha expression, suppressing the TNFalpha-induced invasive capability of MDA-MB-231 human breast cancer cells

Novel inducer of apoptotic cell death in TNBC cell lines without causing cytotoxicity in the normal mammary epithelial cell line

Novel inducer of apoptotic cell death in TNBC cell lines without causing cytotoxicity in the normal mammary epithelial cell line

Novel selective Factor Xa inhibitor, reducing thrombus formation with low risk of bleeding

Parasympathomimetic with longer duration of action

Antibiotic, specifically inhibiting the initiation of RNA synthesis, binding isohelically to the minor groove of B-DNA at A/T rich sites

Inhibitor of ATPase activity of HSP70

Novel negative allosteric modulator of the mGlu5 receptor

Novel activator of the bone marker alkaline phosphatase (ALP), markedly promoting osteoblast differentiation, including expression of Runx2, Osterix, and Osteocalcin, mediating osteogenesis through activation of p38-β

Potent antagonist of GABA A receptors that contain alpha1 and beta2 subunits

Natural full D1 dopamine receptor agonist

Long-lasting prodrug of nalbuphine, acting as a moderate-efficacy partial agonist or antagonist of the μ-opioid receptor and as a high-efficacy partial agonist of the κ-opioid receptor

Inhibitor of Topoisomerase>DNA topoisomerase II; very potent cytotoxic antitumor agent

Anti-infective agent against certain protozoa such as Babesia, Trypanosoma, Cytauxzoon, and certain bacteria including Brucella and Streptococcus

Novel analog of etomidate, potently inhibiting 11-beta-hydroxylase without GABAA receptor positive modulatory and sedative-hypnotic activities

Serotonin antagonist and histamine antagonist