Novel activator of nuclear factor-erythroid-related factor 2 (Nrf-2)

Novel inducer of autophagic cell death through regulating PI3 kinase class III/beclin 1/Atg-related proteins in cisplatin-resistant CAR human oral cancer cells

Peptide hormone that causes vasoconstriction and an increase in blood pressure

Novel angiogenesis agent, showing better efficacy than salidroside in enhancing the accumulation of the HIF-1α protein and stimulating the paracrine functions of skeletal muscle cells, significantly increasing the angiogenic potential of vascular endothel

Novel anticancer agent against metastatic Castration resistance and neuroendocrine variant prostate cancers (mCRPC/NEPC), exhibiting synergistic anticancer effect in combination with standard therapy docetaxel and cabazitaxel in mCRPC/NEPC, upregulating H

Novel Potent Anticonvulsant Agent with In Vitro Neuroprotection

Anticholinergic agent

Novel anti-filariasis agent, being effective in killing Brugia malayi, B. pahangi, and Litomosoides sigmodontis worms

Inhibitor of TLR2-, TLR3-, TLR4- and TLR5-mediated TNF-α, IL-1β and IL-6

Novel potent and selective leucyl-tRNA synthetase inhibitor

Novel Neuraminidase (NA) inhibitor

Novel Anti-Wolbachia Agent with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis

DNA polymerase lambda and beta inhibitor

Novel inhibitor of the replication of a disease-causing polyomavirus in cell culture

Novel small molecule prodrug for use with SEAKER cells, exhibiting enhanced anticancer activity

Novel potent inhibitor of peroxiredoxin I (PrxI), increasing cellular ROS, leading to the activation of both mitochondria- and apoptosis signal-regulated kinase-1-mediated signaling pathways

Novel Metallo-β-lactamase Inhibitor

Novel agonist of AMPK signaling

Potent allosteric activator of the AMPK

Potent allosteric activator of AMPK

Novel rapid and specific inhibitor of electrophile-sensitive DEAD-box proteins with high selectivity over the wild-type enzyme

The most potent AMPA stabilizer

Potent A1/A2A adenosine receptor agonist, protecting against myocardial infarction

Light-activated DNA, RNA crosslinking agent

L-type calcium channel blocker

Inhibitor of the re-uptake of norepinephrine and serotonin, inhibiting N-methyl-D-aspartate (NMDA) receptors

Immunomodulator

NSAID (non-steroidal anti-inflammatory drug) and non selective COX inhibitor

Radiation-protective agent, causing splenic vasodilation and blocking autonomic ganglia

Cysteine trapping agent, protecting cysteines exposed to the aqueous environment from subsequently added mal-PEG