Clickable PPARγ inhibitor

Potent and selective L1196M ALK and ROS1 dual inhibitor

Prodrug of the anthracycline antibiotic doxorubicin, binding selectively to the cysteine-34 position of albumin via its maleimide moiety, inhibiting DNA synthesis, and inducing apoptosis

Novel ALDH inhibitor, inhibiting ALDH3A1 activity in SCC4 HNSCC xenografts

Potent and specific covalent inhibitor of aldehyde dehydrogenases

Novel activator of ALDH3A1

Neuromuscular blocking (NMB) agent

Novel nucleoside phytotoxin

Natural antitumor agent, inducing caspase-dependent apoptosis and ferroptosis as a p53 activator through the mitochondrial pathway

Potent DNA gyrase inhibitor

Potent analgesic, psychotomimetic or hallucinogen, and morphine or opioid antagonist

α-Linolenic acid-Valproic acid conjugate, not only modulating microglia polarization, but also counteracting neurodegeneration and demyelination and induce oligodendrocyte precursor cell differentiation, by acting on multiple biochemical and epigenetic pa

Novel anti-MRSA antibacterial agent, targeting infections caused by Gram-positive bacteria

Novel HCV NS5B Polymerase Inhibitor for the Treatment of Chronic Hepatitis C

Non-steroidal selective modulator for the glucocorticoid receptor (GR)

Potent, selective, and efficacious ocular hypotensive serotonin-2 receptor agonist

Cell-permeable Akt1/2 inhibitor with improved solubility and Ak2 selectivity

Novel potent and selective aldo-keto reductase 1C3 inhibitor, displaying selectivity for AKR1C3 over other AKR1C enzymes and COX

Novel S1P1 agonist

Novel inhibitor of p38 MAP kinase

Novel Inhibitor of EGF-EGFR Interactions

Novel and potent PAK1 (p21-activated kinase 1) inhibitor, suppressing the proliferation of human gastric cancer cells significantly by downregulation of PAK1-NFκB-CyclinB1 pathway

Novel antiproliferative agent

Novel protein kinase C (PKC) activator, preferentially binding to the novel PKC isoforms PKCδ and PKC∈, stimulated a striking preferential redistribution of PKC∈ to the plasma membrane relative to PKCα, inducing major changes in cytoskeletal reorganizatio

Novel β3-Adrenoceptor agonist, reducing body fat in obese beagles

Novel inhibitor of long chain fatty acid elongase 6 (ELOVL6)

Novel FMS-like tyrosine kinase 3 (FLT3) inhibitor, showing improved anti-leukemic efficacy in FLT3-ITD-positive AML cells, specifically inhibiting cell growth and apoptotic death, down-regulating DNA repair genes involved in homologous recombination and n

Novel quorum sensing (QS) signaling molecule produced by Staphylococcus aureusagr type IV

Natural selective inhibitor of IKKα/β by covalently binding a conserved cysteine

Microtubule>Tubulin polymerization inhibitor with marked antitumor activities