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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC77908 | ALG-097558 |
ALG-097558 is an orally active 3CLpro inhibitor. ALG-097558 demonstrates pan-coronavirus activity against various SARS-CoV-2 variants as well as other human coronaviruses (HCoVs) such as SARS-CoV-1, α-HCoV 229E, and β-HCoV OC43. ALG-097558 demonstrates potent inhibition with IC50s of 2 nM (SARS-CoV-2 3CLpro) and 6 nM (229E 3CLpro). ALG-097558 demonstrates antiviral activity in the SARS-CoV-2 hamster infection model. ALG-097558 can be used for the study of viral infections[1].
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| DC77907 | GPI2A |
GPI2A is a 20-mer antisense oligonucleotide sequence that is complementary to a region of the HIV-1 gag gene. GPI2A shows a significant inhibitory effect on p55 and its cleavage product p39/41.
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| DC77906 | GPI2A sodium |
GPI2A sodium is a 20-mer antisense oligonucleotide sequence that is complementary to a region of the HIV-1 gag gene. GPI2A shows a significant inhibitory effect on p55 and its cleavage product p39/41.
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| DC77905 | GNKG168 |
GNKG168 is a synthetic, 21-mer, unmethylated CpG oligodeoxynucleotide. It acts as a TLR9 agonist with immunostimulatory activity.
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| DC77904 | GNKG168 sodium |
GNKG168 sodium is a synthetic, 21-mer, unmethylated CpG oligodeoxynucleotide. It acts as a TLR9 agonist with immunostimulatory activity.
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| DC77903 | GD3 Ganglioside ammonium |
GD3 Ganglioside ammonium is a prominent ganglioside of human melanoma. GD3 Ganglioside ammonium is an inducer of mitochondrial permeability. GD3 ganglioside ammonium directly targets mitochondria in a bcl-2-controlled fashion. GD3 ganglioside ammonium is rapidly synthesized from accumulated ceramide after the clustering of death-inducing receptors and triggers apoptosis.
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| DC77902 | Gatuzosiran |
Gatuzosiran, a siRNA,is a 17-beta-hydroxysteroid dehydrogenase 13 (HSD17B13) synthesis reducer. It is used for the study of fatty liver disease.
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| DC77901 | Gatuzosiran sodium |
Gatuzosiran sodium, a siRNA,is a 17-beta-hydroxysteroid dehydrogenase 13 (HSD17B13) synthesis reducer. It is used for the study of fatty liver disease.
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| DC77900 | Gataparsen |
Gataparsen is an antisense oligonucleotide directed against survivin mRNA with potential antitumor activity.
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| DC77899 | Gataparsen sodium |
Gataparsen sodium is an antisense oligonucleotide directed against survivin mRNA with potential antitumor activity.
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| DC77898 | GalNac-siRNA negative control (21nt) |
GalNac-siRNA negative control (21nt) is the negative control form of GalNac-siRNA. GalNac-siRNA is an Asialoglycoprotein receptor (ASGPR)-targeted inhibitor conjugate. GalNac-siRNA is promising for research of hereditary transthyretin amyloidosis, acute hepatic porphyria, hemophilia and hypercholesterolemia.
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| DC77897 | Etidaligide |
Etidaligide, an AsiDNA, a first-in-class DNA repair inhibitor designed to prevent the repair of DNA damage in tumour cells. It also activates DNA-dependent protein kinase (DNA-PK) and poly (ADP-ribose) polymerase enzymes that induce phosphorylation of H2A
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| DC77896 | Etidaligide sodium |
Etidaligide sodium, an AsiDNA, a first-in-class DNA repair inhibitor designed to prevent the repair of DNA damage in tumour cells. It also activates DNA-dependent protein kinase (DNA-PK) and poly (ADP-ribose) polymerase enzymes that induce phosphorylation
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| DC77895 | Erisonersen |
Erisonersen, an antisense oligonucleotide, is a prion protein synthesis reducer. It is used for the study of Prion disease.
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| DC77894 | Erisonersen sodium |
Erisonersen sodium, an antisense oligonucleotide, is a prion protein synthesis reducer. It is used for the study of Prion disease.
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| DC77893 | Edutirsen |
Edutirsen, an antisense oligonucleotide, is a 1-acylglycerol-3-phosphate O-acyltransferase (PNPLA3) synthesis reducer.
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| DC77892 | Edutirsen sodium |
Edutirsen sodium, an antisense oligonucleotide, is a 1-acylglycerol-3-phosphate O-acyltransferase (PNPLA3) synthesis reducer.
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| DC77891 | Edifoligide |
Edifoligide is a decoy oligonucleotide that binds to and inhibits E2F transcription factors and thus may prevent neointimal hyperplasia and vein graft failure
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| DC77890 | Edifoligide sodium |
Edifoligide sodium is a decoy oligonucleotide that binds to and inhibits E2F transcription factors and thus may prevent neointimal hyperplasia and vein graft failure
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| DC77889 | Ecad saRNA |
Ecad saRNA is a small activating RNA (saRNA) targeting the E-cadherin genes. Ecad saRNA induce expression of the E-cadherin genes, and targets the E-cadherin promoters at ?215 relative to gene's transcription start site.
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| DC77888 | dsP53-285 saRNA |
dsP53-285 saRNA is a small activating RNA (saRNA) that readily activates wild-type p53 expression by targeting its promoter. dsP53-285 saRNA suppresses bladder cancer cells growth and metastasis.
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| DC77887 | DNMT1 aptamer sodium |
DNMT1 aptamer sodium is a DNA aptamer for binding and inhibition of DNA methyltransferase 1 (DNMT1).
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| DC77886 | Diranersen |
Diranersen, an antisense oligonucleotide, is a tau protein synthesis reducer. It is used for the study of Alzheimer's disease.
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| DC77885 | Diranersen sodium |
Diranersen sodium, an antisense oligonucleotide, is a tau protein synthesis reducer. It is used for the study of Alzheimer's disease.
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| DC77884 | Daplusiran |
Daplusiran is a siRNA in JNJ-3989 (JNJ-73763989). JNJ-3989 is comprised of 2 siRNAs (Daplusiran and Tomligisiran), that target hepatitis B virus (HBV) mRNAs for degradation, thereby inhibiting HBV replication.
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| DC77883 | Daplusiran sodium |
Daplusiran sodium is a siRNA in JNJ-3989 (JNJ-73763989). JNJ-3989 is comprised of 2 siRNAs (Daplusiran and Tomligisiran), that target hepatitis B virus (HBV) mRNAs for degradation, thereby inhibiting HBV replication.
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| DC77882 | Cupabimod |
Cupabimod is a decoy oligodeoxynucleotide for transcription factor NF-κB.
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| DC77881 | Cupabimod sodium |
Cupabimod sodium is a decoy oligodeoxynucleotide for transcription factor NF-κB.
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| DC77880 | CpG-ODN c41 |
CpG-ODN c41, an oligonucleotide, is an antagonist of TLR9.
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| DC77879 | CpG-ODN c41 sodium |
CpG-ODN c41 sodium, an oligonucleotide, is an antagonist of TLR9.
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