BDP FL DBCO is a PEG derivative containing a reactive DBCO group. DBCO will react with azide-bearing compounds or biomolecules to form a stable triazole linkage without copper catalyst.

Sulfo DBCO-PEG4-amine is a water-soluble carboxyl-reactive building block with extended PEG spacer arm. In the presence of of activators (e.g. EDC, or DCC), this reagent can be used to derivatize carboxyl groups or activated esters (e.g. The NHS ester) through a stable amide bond. The hydrophilic sulfonated spacer arm greatly improves water solubility of DBCO derivatized molecules and a provides a long and flexible connection.

Acid-PEG4-S-S-PEG4-acid is a cleavable PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.

Acid-PEG3-SS-PEG3-acid is a cleavable PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.

Bromoacetamido-PEG8-t-butyl ester is a PEG derivative containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Bromo-PEG6-azide is a PEG derivative containing a bromide group and a terminal azide. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.

Bromo-PEG3-CH2CO2tBu is a PEG derivative containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

t-Boc-N-Amido-PEG7-propargyl is a PEG derivative containing a propargyl group and Boc-protected amino group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine.

t-Boc-N-Amido-PEG5-propargyl is a PEG derivative containing a propargyl group and Boc-protected amino group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Azido-PEG2-t-Boc-hydrazide is a PEG derivative containing an azide group and a Boc-protected hydrazide. The azide group can react with alkyne groups, BCN, and DBCO via Click Chemistry to yield a stable triazole linkage. The Boc can be deprotected under mild acidic conditions to form a reactive hydrazide, which can then be coupled with various carbonyl groups.

t-boc-N-amido-PEG9-azide is a PEG derivative containing an azide group and Boc-protected amino group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine.

t-boc-N-amido-PEG7-azide is a PEG derivative containing an azide group and Boc-protected amino group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine.

t-Boc-N-amido-PEG5-NHS ester is a PEG derivative containing an NHS ester and a Boc-protected amino group. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

t-Boc-N-amido-PEG7-acid is a PEG derivative containing a terminal carboxylic acid and Boc-protected amino group. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Bis-PEG10-acid is a PEG derivative containing two terminal carboxylic acid groups. The terminal carboxylic acids can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of antibody drug conjugates (ADCs).

N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester is a Biotin PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.

2-(Biotin-amido)-1,3-bis(carboxylethoxy)propane is a Biotin PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.

N-(Biotin-PEG4)-N-bis(PEG4-acid) HCl salt is a PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.

N-(Biotin)-N-bis(PEG1-alcohol) is a PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.

N-(Propargyl-PEG4)-biocytin is a biotin PEG derivative containing a carboxylic group and an alkyne group. Reaction of carboxylic with primary amino (-NH2) forms stable, irreversible amide bonds. The alkyne group can react with azide moiety in Cu(I)-catalyzed Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound.

N-(Azido-PEG4)-biocytin is a biotin PEG derivative containing a carboxylic group and an azide group. Reaction of carboxylic with primary amino (-NH2) forms stable, irreversible amide bonds. The azide group can react with alkyne moiety in Cu(I)-catalyzed Click Chemistry reaction or DBCO moiety in copper-free Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound.

Dde Biotin-PEG4-Picolyl azide is a cleavable reagent containing a biotin moiety and a picolyl azide moiety which can be conjugated with alkyne-containing biomolecules. This biotin reagent incorporates a copper-chelating motif that dramatically accelerates the Cu(I)-catalyzed Click Chemistry. Dde protecting group allows efficient release of captured biotinylated molecules from streptavidin under mild conditions with hydrazine.

Biotin-PEG12-TFP ester with primary amino (-NH2) forms stable, irreversible amide bonds. The hydrophilic PEG spacer arm imparts water solubility that is transferred to the biotinylated molecule. Therefore, Biotin-PEG-TFP esters may be useful in the development of antibody drug conjugates.

Biotin-PEG6-NHS ester is PEG derivative containing a biotin group and an NHS ester group. The NHS group reacts specifically and efficiently with lysine and N-terminal amino groups at pH 7-9 to form stable amide bonds. PEG Linkers may be useful in the development of antibody drug conjugates.

Benzyloxy carbonyl-PEG3-NHS ester is a Benzyl PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.

Benzyloxy carbonyl-PEG3-acid is a Benzyl PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.

N-(Aminooxy-PEG3)-N-bis(PEG4-t-butyl ester) is an Aminooxy PEG Linker. Aminooxy-PEG can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage.

Fmoc-aminooxy-PEG12-acid is an Aminooxy PEG Linker. Aminooxy PEGs may be useful in bioconjugation experiments.

t-Boc-Aminooxy-PEG3-oxyamine is an Aminooxy PEG Linker. These PEG Linkers may be useful in bioconjugation experiments.

t-Boc-Aminooxy-PEG7-methane is a crosslinker containing a t-Boc-aminooxy group and a methane group. The protected amine can be deprotected under mild acidic conditions. Aminooxy PEG Linkers may be useful in bioconjugation experiments.