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Cat. No. Product Name Field of Application Chemical Structure
DC37569 Atraton
Atraton is an Agricultural Chemical.
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DC35975 TCO-amine hydrochloride
TCO-amine hydrochloride is a simple building block containing a TCO moiety and a free amine. This reagent can be used to derivatize carboxyl groups or activated esters (e.g. NHS esters) with the TCO moiety through a stable amide bond in the presence of of activators (e.g. EDC, or DCC). The low mass weight will add minimal spacer to modified molecules.
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DC37776 L-Dithiothreitol
L-Dithiothreitol is a chiral bidentate dithiol with two stereogenic centers, may be used in chiroptical response research. L-DDT is proposed as a stereoselective reducing agent for disulfide bridges in complex molecules.
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DC34815 Propargyl-PEG4-Maleimide
Propargyl-PEG4-Maleimide is a PEG derivative containing a propargyl group and a maleimide group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The terminal alkyne will react with azides via copper-catalyzed Click Chemistry. PEG Linkers are useful for the development of antibody drug conjugates.
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DC34221 PF2562
PF2562 is a non-catechol dopamine 1 receptor agonist. Dopamine D1 receptors are implicated in numerous neuropharmacological and neurobiological functions. For example, D1 receptors are involved in different types of memory function and synaptic plasticity.
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DC35964 Azido-PEG4-beta-D-glucose
Azido-PEG4-beta-D-glucose is a PEG derivative containing one azide group and one D-glucose group. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media. D-glucose increases solubility in aqueous media and increases the selectivity of the PEGylation reaction.
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DC34851 endo-BCN-PEG8-NHS ester
endo-BCN-PEG8-NHS ester is a PEG derivative containing an NHS ester group and a BCN group. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The BCN group can react with azide-tagged biomolecules. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC36416 LL-D 37187α
Martinomycin is a polyether antibiotic active against a variety of bacteria including 11 strains of S. aureus, three strains of S. pneumoniae, and E. faecalis.
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DC35895 PEG3-bis-(ethyl phosphonate)
PEG3-bis-(ethyl phosphonate) is a PEG Linker.
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DC37929 (R)-Lamivudine sulfoxide
Lamivudine sulfoxide, (R)- is a metabolite of Lamivudine; a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has been used for treatment of chronic hepatitis B.
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DC34458 EPPS
EPPS is a rescuer of A? aggregation and behavioural deficits, binding to A? aggregates and converting them into monomers.
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DC33860 Sulfo-Cyanine 7 NHS ester
Sulfo-Cyanine7 is an improved analog of Cy7 fluorophore with higher quantum yield and photostability. This fluorescent dye is especially useful for NIR imaging. Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and drug design related experiments.
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DC37206 Ethyl phenylglyoxylate
Ethyl phenylglyoxylate is a simultaneous inhibitor and substrate of chicken liver carboxylesterase
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DC35811 Mal-PEG6-PFP
Mal-PEG6-PFP is a PEG Linker.
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DC35804 Mal-PEG6-NHS ester
Mal-PEG6-NHS ester is a PEG derivative containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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DC37950 Alachlor
Alachlor is a herbicide and pesticide.
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DC33898 Cyanine5.5 maleimide
Cyanine5.5 maleimide is a thiol reactive dye which is capable of selective labeling of sulfhydryl groups in proteins, an analog of Cy5.5? maleimide. Near infrared emission of Cyanine5.5 makes this dye suitable for bioimaging applications. Cyanine5.5 can replace Cy5.5?, Alexa Fluor 680, and DyLight 680.
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DC34817 Bis-propargyl-PEG5
Bis-propargyl-PEG5 is a crosslinker containing two propargyl groups at each terminal end. The propargyl groups can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages.
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DC36454 Carboxyibuprofen
Ibuprofen carboxylic acid is a major metabolite of ibuprofen.
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DC37150 Calcium stearate
Calcium Stearate as an Effective Alternative to Poly(vinyl alcohol) in Poly-Lactic-co-Glycolic Acid Nanoparticles Synthesis.
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DC37869 N-Iminoethyl-L-lysine dihydrochloride
L-NIL HCl is a relatively selective inhibitor of iNOS. It exhibits IC50 values of 0.4-3.3 μM for iNOS as opposed to 8-38 and 17-92 μM for eNOS and nNOS, respectively. L-NIL effectively inhibits iNOS both in vitro and in vivo.4,5,3 L-NIL has been used to demonstrate a critical role for iNOS in the immune response to infection by the protozoan L. major.
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DC35174 N-Boc-PEG12-alcohol
N-Boc-PEG12-alcohol is a PEG derivative containing a hydroxyl group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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DC34554 3F-8
3F8 is a selective and potent GSK-3? inhibitor.
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DC34732 LC-SPDP Crosslinker
LC-SPDP Crosslinker, also known as SPDP-C6-NHS ester, is a cleavable, water insoluble, amino and thiol (sulfhydryl) reactive heterobifunctional crosslinking reagent. The "long chain" LC-SPDP crosslinking reagent has a 15.7 angstrom spacer arm, compared to the shorter 6.8 angstrom spacer arm version of SPDP crosslinker. Often, due to steric hindrances, it is desirable to empirically test which of the two versions will work best in your specific application. LC-SPDP Crosslinker is useful for making Antibody Drug Conjugates (ADCs).
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DC37840 Pralmorelin
Pralmorelin (free base) stimulates growth hormone secretion.
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DC36611 Desbutylbupivacaine
Desbutylbupivacaine also known as N-Desbutyl Bupivacaine, it is a major metabolite of Bupivacaine.
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DC36394 Collismycin A
Collismycin A is a bacterial metabolite with antibacterial, antiproliferative, and neuroprotective properties. It is active against a variety of bacteria and fungi. It inhibits proliferation of A549 lung, HCT116 colon, HeLa cervical cancer cells, and NIH373 fibroblasts but not MDA-MD-231 breast cancer cells. Collismycin A forms a complex with Fe(II) and Fe(III) at a 2:1 ratio, and the addition of iron ions inhibits the antiproliferative effect of collismycin A on HeLa cells, an effect that does not occur with the addition of zinc, manganese, copper, or magnesium ions. Collismycin A (1 μM) prevents apoptosis in the brain region of zebrafish larvae by 44% in a model of neuronal cell death induced by all-trans retinoic acid.
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DC36424 BODIPY 558/568 C12
BODIPY 558/568 C12 is a fatty acid-conjugated fluorescent probe for lipid droplets. It displays excitation/emission maxima of 558/568 nm, respectively, and has been used to monitor the localization and dynamics of lipid droplets in live cells.
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DC34449 Dofequidar fumarate
Dofequidar fumarate is a potent inhibitor of MDR-1.
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DC34605 aPKCI
aPKC-I is an inhibitor of atypical protein kinase C (aPKC ) which inhibits both PKCζ and PKCι with high specificity and prevents VEGF-induced endothelial permeability in cell culture and in vivo, thereby blocking ischemia-reperfusion (IR)-induced permeability.
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