Triadimenol is a flammable white to gray solid with phenolartigem odor which is practically insoluble in water. It decomposes when heated above 150 ° C. The compound is present in several isomeric front forms, the technical product to 78 to 88% of the diastereoisomer A is (RS + SR). The compound is stable to hydrolysis at pH values ??of 4, 7 and 9 and is subject to a small extent of photolysis. Triadimenol is a systemic fungicide with a broad spectrum. It inhibits the ergosterol - and gibberellin - biosynthesis , and thus the rate of cell division.

SKF1 is a suppressor of the ability of FK506 to inhibit cell growth in the presence of high levels of NaCl, inducing cell death in low salt conditions, interacting directly with yeast mitochodria.

Triadimefon is an azole fungicide.

TMI-1 is a novel orally active inhibitor of ADAM17 (TACE) and MMP, inducing tumor apoptosis in a breast cancer.

Tomelukast, also known as LY171883, is a leukotriene inhibitor. Tomelukast showed protective effects in traumatic shock. LY-171883 stimulates the activity of BK(Ca) channels in a manner unlikely to be linked to its blockade of leukotriene receptors or stimulation of peroxisome proliferator-activated receptors. The stimulatory effects on these channels may, at least in part, contribute to the underlying cellular mechanisms by which LY-171883 affects neuronal or neuroendocrine function.

MAFP is an irreversible inhibitor of Ca(2+)-independent phospholipase A2 (iPLA2).

Proxyfan Oxalate is a potent histamine H3 receptor ligand, acting as a protean agonist with activity ranges from full agonist to inverse agonist depending on system used. also displaying partial agonist effects on cAMP inhibition and MAPK activity, neutral antagonist activity on histamine release and partial inverse agonism of [3H]-arachidonic acid release.

Thiolactomycin is a novel reversible dual inhibitor of D-Aspartate oxidase (DDO) and D-amino acid oxidase (DAO).

Tebuconazole is a triazole fungicide used agriculturally to treat plant pathogenic fungi. Though the U.S. Food and Drug Administration considers this fungicide to be safe for humans, it may still pose a risk. It is listed as a possible carcinogen in the United States Environmental Protection Agency Office of Pesticide Programs carcinogen list with a rating of C (possible carcinogen). Its acute toxicity is moderate. According to the World Health Organization toxicity classification, it is listed as III, which means slightly hazardous.

AZ-PFKFB3-67 is a novel potent and selective PFKFB3 inhibitor.

Z-LLNle-CHO, also known as gamma-Secretase Inhibitor I, is a cell permeable inhibitor of gamma-secretase, inducing apoptosis of human glioblastoma tumor-initiating cells by proteasome inhibition and mitotic arrest response.

FKGK11 is a novel potent inhibitor of GVIA iPLA2 with little or no inhibition against GIVA cPLA2 (XI(50) = 0.0073 and >0.91, respectively).

HUN85199, also known as B-Raf inhibitor 1 dihydrochloride, is a novel potent and selective B-Raf inhibitor. HUN85199 has CAS#1191385-19-9, was first reported in Journal of Medicinal Chemistry (2009), 52(20), 6189-6192. It has no code name. For the convenience of scientific communication, we name it as HUN85199 by using CAS# ahdn inchi key as proposed by Hodoodo Chemical Nomenclature (see https://hodoodo.com/hodoodo-chemical-nomenclature).

Sulbactam pivoxil, also known as CP-47904 and Pivsulbactam, is an irreversible inhibitor of β-lactamase; it binds to the enzyme and does not allow it to degrade the antibiotic.

Sudoxicam is a nonsteroidal anti-inflammatory drugs (NSAIDs) from the enol-carboxamide class.

Sulfamonmethoxine is a competitive inhibitor of dihydropteroate synthetase, blocking the synthesis of folic acid.

MHY908 is a novel inhibitor of melanogenesis, potently inhibiting mushroom tyrosinase activity in a dose-dependent manner.

CP-944629 is a novel, potent, and selective p38alpha inhibitor.

BMS-770767 is a novel inhibitor of 11-betahydroxysteroid dehydrogenase type I (11?-HSD1).

Sofalcone is an oral gastroprotective, gastrointestinal medication. It is a synthetic analog of sophoradin.

HA-1004 is an inhibitor of PKA, cGKI, PKC, MYLK, and calcium channel protein.

Pyrabactin is a plant growth inhibitor, acting as a seed-selective abscisic acid (ABA) agonist; Novel PYL agonist.

Triclabendazole is an anthelmintic and fasciolicidal, binding to beta-tubulin and preventing the polymerization of the microtubules of which they are part. Studies in vitro and/or in infected animals suggest that triclabendazole and its active metabolites (sulfoxide and sulfone) are absorbed by the tegument of the immature and mature worms, leading to a decrease of the resting membrane potential, inhibition of tubulin function as well as protein and enzyme synthesis. These metabolic disturbances are associated with inhibition of motility, disruption of the surface as well as ultrastructure that includes inhibition of spermatogenesis and vitelline cells.

SB 224289 is a selective 5-HT1B receptor antagonist (pKi = 8.2). SB 224289 displays > 60-fold selectivity over 5-HT1D, 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A and 5-HT2C receptors in radioligand binding and functional assays. SB 224289 is a centrally active following oral administration in vivo.

Suprafenacine is a novel cell permeable selective inhibitor of cancer cell proliferation, binding microtubules at the colchicine-binding site and inhibiting polymerization, leading to G2/M cell cycle arrest and cell death via a mitochondria-mediated apoptotic pathway.

TBMP is a novel inhibitor of the viral envelope protein hemagglutinin (HA)-mediated entry.

Ro 24-7429 is a Tat antagonist. Ro 24-7429 blocks the action of the HIV tat protein and is an analog of Ro 5-3335.

Aminotadalafil is an analog of Tadalafil as a phosphodiesterase type 5 (PDE-5) inhibitor.

2-DG is an inhibitor of glycolysis via its actions on hexokinase, the rate limiting step of glycolysis.

Cyclo-L-Trp-L-Trp is a broad spectrum antifungal, inducing a high degree of acetylation of histones.