Cat. No. | Product Name | Field of Application | Chemical Structure |
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DC21496 | PF-03382792 |
PF-03382792 (PF-3382792) is a clinical compound under phase 1 investigation for an unknown indication..
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DC21470 | PF-03049423 |
PF-03049423 is a potent, selective, orally active, and brain penetrant inhibitor of PDE5 with IC50 of 0.2 nM.
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DC23574 | PF-02575799 |
PF-02575799 is a highly potent microsomal triglyceride transfer protein (MTP) inhibitor with IC50 of 0.77 nM.
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DC21495 | PF-02413873 |
PF-02413873 (PF-2413873) is a potent, selective, fully competitive, and orally active progesterone receptor (PR) antagonist with Ki of 9.7 nM.
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DC21500 | PF-00610355 |
PF-00610355 (PF 610355) is a potent, selective, and long-acting β2-adrenoreceptor agonist with EC50 of 0.26 nM.
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DC21516 | PF 5212372 |
PF 5212372 (PLA-950, ZPL-521, ZPL 5212372) is a potent, selective inhibitor of cPLA2 (cytosolic phospholipase A2α) with IC50 of 7 nM.
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DC8147 | PF 4800567 |
PF 4800567 is a selective casein kinase 1ε inhibitor; displays 22-fold greater potency towards CK1ε than CK1δ (IC50 values are 32 and 711 nM for CK1ε and CK1δ respectively).
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DC12192 | PF 03709270 (ulopenem etzadroxil) |
PF 03709270 is an orally available ester prodrug form of sulopenem, with broad-spectrum antibacterial activity against most gram-positive and gram-negative bacteria.
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DC12207 | Petroselinic acid |
Petroselinic acid, a positional isomer of oleic acid, is isolated from the vegetable oil of Coriandrum sativum fruits.
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DC20708 | Perlapine |
Perlapine (AW-14233.
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DC12137 | Perisesaccharide C |
Perisesaccharide C is an oligosaccharide isolated from the root barks of Periploca sepium.
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DC12139 | Perisesaccharide B |
Perisesaccharide B is an oligosaccharide isolated from the root barks of Periploca sepium.
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DC9143 | Perindopril erbumine |
Perindopril erbumine is a potent ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease.
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DC20495 | Perhexiline |
Perhexiline is a prophylactic antianginal agent that inhibits carnitine palmitoyltransferase (CPT1/CPT2).
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DC20494 | Peptide Fz7-21 |
Peptide Fz7-21 is a potent, selective peptide inhibitor of Frizzled 7 receptor, inhibits exogenous WNT3A stimulated Wnt-β-catenin signaling in HEK293 cells with IC50 of 100 nM.
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DCAPI1224 | Penicillamine (Cuprimine) |
Penicillamine (Cuprimine)
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DCAPI1314 | Pefloxacin mesylate |
Pefloxacin mesylate
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DC23807 | PDEδ-IN-99 |
PDEδ-IN-99 is a novel potent K-Ras-PDEδ inhibitor that binds to the farnesyl binding pocket of PDEδ with Kd of 8±4 nM..
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DC23698 | PDE4D-IN-26b |
PDE4D-IN-26b is a potent, highly selective PDE4D inhibitor with IC50 of 0.6 nM, displays 75-fold lower activity against the PDE4A, B, and C subtypes, also exhibits 18,000-fold decreased potency against other PDE family members.
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DC12555 | PDE2 inhibitor 4 |
PDE2 inhibitor 4 is a potent, selective, orally available inhibitor of PDE2 with IC50 of 2 nM, displays high selectivity versus other PDE isoforms.
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DC23701 | PDE10A-IN-32 |
PDE10A-IN-32 is a potent, highly selective, brain penetrant PDE10A inhibitor with IC50 of 0.14 nM, displays no significant activity against other PDEs (IC50>1,000 nM)..
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DC23693 | PDE10A-IN-31 |
PDE10A-IN-31 is a potent, highly selective PDE10A inhibitor with IC50 of 2 nM for both rPDE10A and hPDE10A.
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DC21936 | PD1-PD L1 inhibitor Polaris |
PD1-PD L1 inhibitor Polaris is a novel potent, small molecule inhibitor of PD-1/PD-L1 interaction (IC50=0.1-10 nM in ELISA assays) with anti-cancer activity.
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DC12219 | PD1-IN-2 |
PD1-IN-2 is a PD1 signaling pathway inhibitor, which acts as an immunomodulator.
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DC23758 | PCSK9-IN-7l |
PCSK9-IN-7l is a potent, small molecule PCSK9 mRNA translation inhibitor with IC50 of 1.37 uM, shows limited bone marrow toxicity (IC50=27.1 uM)..
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DC23759 | PCSK9 modulator 10 |
PCSK9 modulator 10 is a highly potent, orally active PCSK9 modulator that inhibits PCSK9 production in HepG2 cells with IC50 of 0.036 nM.
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DC12080 | PCI-33380 |
PCI-33380 is an irreversible Bruton's Tyrosine Kinase (BTK) inhibitor (fluorescent probe).
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DC23651 | PCARBTP |
PCARBTP is a derivative, potent, specific Kv1.3 channel inhibitor, reduces cell viability and efficiently kills B16F10 cancer cells at 1 uM.
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DC23061 | L-45 |
PCAF BRD inhibitor L-45 is a potent, selective, and cell-active PCAF bromodomain inhibitor with Ki of 47 nM in HTRF assays, >4,500-fold selectivity over BRD4.
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DC21460 | PC945 |
PC945 is a novel broad spectrum antifungal agent that potently inhibits Aspergillus fumigatus sterol 14α-demethylase (CYP51A and CYP51B) with IC50 of 0.23 and 0.22 uM, respectively.
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