Cat. No. | Product Name | Field of Application | Chemical Structure |
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DC22177 | NLY01 |
NLY01 (NLY-01, GLP1R agonist NLY01) is a potent, brain-penetrant long-acting GLP1R agonist, protects against the loss of dopaminergic neurons and behavioral deficits in the α-synuclein preformed fibril (α-syn PFF) mouse model of sporadic Parkinson's disea
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DC26132 | NLRP3 Inflammasome Inhibitor I |
NLRP3 Inflammasome Inhibitor I, an intermediate substrate in the synthesis of glyburide which is free of the cyclohexylurea moiety involved in insulin release, is a novel inhibitor of the NLRP3 inflammasome.
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DC21388 | NJK14047 |
NJK14047 is a novel potent, selective p38 MAPK inhibitor with IC50 of 27 nM against p38α, suppresses RSV and influenza A virus replication by inhibiting virus-induced p38 MAPK activation.
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DC9085 | Nitrendipine |
Nitrendipine is a calcium channel blocker with marked vasodilator action.
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DC21386 | NITD-916 |
NITD-916 is a novel, direct inhibitor of the mycobacterial enoyl-reductase InhA with IC50 of 0.57 uM, exhibits MIC50 of 50 nM against Mtb.
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DC21385 | NITD-564 |
NITD-564 is a novel, direct inhibitor of the mycobacterial enoyl-reductase InhA with IC50 of 0.59 uM, exhibits MIC50 of 160 nM against Mtb.
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DC21384 | NITD-349 |
NITD-349 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 23 nM against M tuberculosis H37Rv.
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DC21383 | NITD-304 |
NITD-304 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 15 nM against M tuberculosis H37Rv.
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DC9052 | Nimesulide |
Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties.
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DC9379 | Nilvadipine |
Nilvadipine(FR34235) is a calcium channel blocker for treatment of hypertension.
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DC4192 | Nilutamide |
Nilutamide is an antiandrogen medication used in the treatment of advanced stage prostate cancer.
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DC12297 | Nigakinone |
Nigakinone is one of the most abundant alkaloids responsible for the major pharmacological activities of Kumu.
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DCAPI1571 | Nifuratel |
Nifuratel
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DC9079 | Nifedipine |
Nifedipine(Adalat), a potent vasodilator agent with calcium antagonistic action.
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DC9068 | Niclosamide |
Niclosamide(BAY2353) is used for the treatment of most tapeworm infections by inhibiting DNA replication.
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DC25090 | Nicardipine |
Nicardipine(YC-93) is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage..
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DC21742 | NIBR-3049 |
NIBR-3049 (TCS-21311) is a potent, highly selective JAK3 inhibitor with IC50 of 8 nM, displays >100-fold selectivity over JAK1, JAK2 and TYK2, also inhibits PKCα, PKCθ, and GSK3β with IC50 of 13, 68, and 3 nM, respectively..
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DC11200 | NGI-1 derivative C-19 |
NGI-1 derivative C-19 is a specific, small-molecule inhibitor of oligosaccharyltransferase (OST) catalytic subunit STT3B, without effect on STT3A.
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DC21380 | NGD-4715 |
NGD-4715 is a potent, selective, non-peptide antagonist of MCHR1 (Melanin-concentrating hormone receptor 1), has anxiolytic, antidepressant and anorectic effects..
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DC23081 | NFPS |
NFPS (ALX-5407) is a potent, selective GlyT1 inhibitor with IC50 of 2.8 and 9.8 nM for hGlyT1 and rGlyT1 respectively, >5,000-fold selectivity over rGlyT2.
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DC23016 | Nexinhib 20 |
Nexinhib 20 is a novel small molecule neutrophil exocytosis inhibitor (IC50=0.33 uM) that specifically inhibits Rab27a-JFC1 binding (IC50=2.6 uM) but does not interfere with the interaction of other Rab GTPases and effectors.
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DC12238 | Neurotoxin Inhibitor |
Neurotoxin Inhibitor is a neurotoxin inhibitor.
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DC23275 | NEU-1953(NEU1953) |
NEU-1953 (NEU1953) is a potent inhibitor of P. falciparum with EC50 of 0.43 uM (T. brucei), demonstrates improved ADME profile over the NEU-961..
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DC8100 | Netupitant |
Netupitant is a highly potent and selective, orally active neurokinin-1 receptor antagonist with Ki of 0.95 nM.
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DC9353 | Netilmicin (sulfate) |
Netilmicin Sulfate is an active aminoglycoside antibiotic against most Gram-negative and some Gram-positive bacteria, including certain strains resistant to gentamicin.
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DC23057 | Nestorone |
Nestoron2 (ST1435, Elcometrine) is a 19-norprogesterone derivative and steroidal progestin which is used as a hormonal contraceptive, a high-affinity agonist of the progesterone receptor..
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DC22175 | NEO214 |
NEO214 (NEO-214) is a novel, BBB-permeable rolipram-perillyl alcohol conjugate, shows effectivity against both TMZ-sensitive and TMZ-resistant glioma cells (T98G IC50=40 uM).
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DC20744 | Neladenoson dalanate hydrochloride |
Neladenoson dalanate is a potent, selective, orally acitve partial adenosine A1 receptor (A1AR) agonist (EC50=0.1 nM) for the treatment of chronic heart failure..
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DC20743 | Neladenoson dalanate |
Neladenoson dalanate is a potent, selective, orally acitve partial adenosine A1 receptor (A1AR) agonist (EC50=0.1 nM) for the treatment of chronic heart failure..
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DC8194 | PP3 Featured |
Negative control for the Src kinase inhibitor PP2.
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