Nefopanhydrochloride

Nef-IN-B9 (Nef inhibitor B9) is a small molecule that blocks Nef-dependent Hck activity with IC50 of 2.8 uM, while the activity against Hck alone is >20 uM.

Nebicapone (BIA 3-202, BIA3-202) is a potent, long-acting, reversible and competitive peripheral inhibitor of catechol-O-methyltransferase (COMT) with IC50 of 3.7 nM for rat brain COMT, much less potent for liver COMT with IC50 of 696 nM.

NDT 9513727 is a potent, selective and orally bioavailable C5a receptor inverse agonist with IC50 of 11.6 nM in radioligand binding assay.

NCX-4016 (Nitroaspirin.

NCT-502 is a small molecule 3-phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50=3.7 uM) that reduces the production of glucose-derived serine in cells and suppress the growth of PHGDH-dependent cancer cells.

NCGC00185684 (ML154) is a potent, selective, brain penetrant NPSR (Neuropeptide S receptor.

NCGC00071837 (PDE4-IN-5A) is a potent, selective PDE4 inhibitor with IC50 of 24 and 18 nM for PDE4A and PDE4D, respectively, weak inhibition for PDE4B (IC50=0.54 uM) and inactive for PDE1/3/5/7/9/10/11.

NCD-38 is a novel potent, selective LSD1 inhibitor with IC50 of 0.59 uM, exerts highly selective inhibitory activity on LSD1 but no other enzymes, such as MAO (IC50>100 uM).

NCD-25 is a novel potent, selective LSD1 inhibitor with IC50 of 0.48 uM, exerts highly selective inhibitory activity on LSD1 but no other enzymes, such as MAO..

NCC007 is a novel CKIα and CKIδ dual inhibitor. NCC007 that showed stronger period effects (0.32 μM for 5 h period lengthening) in a cellbased circadian assay.

NC-043 (15-Oxospiramilactone) is a diterpenoid derivative inhibitor of Wnt/β-catenin signaling that interferes with the β-catenin/TCF4 association.

NBQX disodium is the water soluble disodium salt of NBQX, which is a potent, selective and competitive AMPA receptor (AMPAR) antagonist with IC50 of 0.15 uM.

NBI-42902 is a potent inhibitor of peptide radioligand binding to the human GnRH receptor (K(i) = 0.56 nm).

NBC19 is a potent inhibitor of NLRP3 inflammasome, inhibits nigericin-induced ASC speck formation in post-differentiated THP1 cells with IC50 of 60 nM..

Nateglinide is an insulin secretagog agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).

Natamycin(Pimaricin)

N-aryl benzimidazole (NAB) is a small molecule that strongly and selectively protects diverse cell types from α-syn toxicity, promotes endosomal transport events dependent on the E3 ubiquitin ligase Rsp5/Nedd4 in wild-type yeast cells..

Naronapride (ATI-7505) is a potent, selective and orally active 5-HT4 receptor agonist with Ki of 1.4 nM.

Naquotinib (ASP-8273) is a potent, irreversible, mutant-selective inhibitor of EGFR (IC50=8-33 nM for (L858R, exon 19 deletion, L858R/T790M, and del19/T790M)).

Naquotinib (ASP-8273) is a potent, irreversible, mutant-selective inhibitor of EGFR (IC50=8-33 nM for (L858R, exon 19 deletion, L858R/T790M, and del19/T790M)).

Naphyrone (O-2482)

Nandrolone is a synthetic, anabolic steroid analog of testosterone.

NAN-190 is a 5-HT1A receptor antagonist with Ki of 0.6 nM.

Nalidixic acid (NegGram)

NAcM-COV is a specific, irreversible small molecule inhibitor targeting N-Acetyl-UBE2M interaction with DCN1 with IC50 of 28 nM in TR-FRET assays.

Nabumetone(BRL14777) is a non-steroidal anti-inflammatory drug and its active metabolite inhibits the COX.

N6-(2-Phenylethyl)adenosine is a selective A1 adenosine receptor agonist.

N3PT(N3-pyridyl thiamine) is a potent and selective transketolase(TK) inhibitor (IC50= 22 nM for Apo-TK) both in vitro and in vivo.

N2-Methylguanine is a modified nucleoside. N2-Methylguanine is an endogenous methylated nucleoside found in human fluids.