Cat. No. | Product Name | Field of Application | Chemical Structure |
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DC74108 | Opabactin |
Opabactin is an abscisic acid (ABA) mimic and agonist Arabidopsis subfamily III/II ABA receptors with nanomolar potency (7 nM).
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DC74107 | NVS1.1 |
NVS1.1 is a potent readthrough promoter, promotes the rapid and specific degradation of eukaryotic release factor 1 (eRF1) and restores functional full-length proteins in cystic fibrosis and Hurler disease models.
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DC74106 | NV930 |
NV930 is a small molecule inhibitor of tRNA-specific 2′-O-methyltransferase (FTSJ1), exerts readthrough activity in vitro and in vivo.
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DC74105 | NV914 |
NV914 is a small molecule inhibitor of tRNA-specific 2′-O-methyltransferase (FTSJ1), exerts readthrough activity in vitro and in vivo.
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DC74104 | NV848 |
NV848 is a small molecule inhibitor of tRNA-specific 2′-O-methyltransferase (FTSJ1), exerts readthrough activity in vitro and in vivo.
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DC74103 | NUP-17d-52A |
NUP-17d-52A (Plek2 inhibitor) is a specific small molecule inhibitor of Pleckstrin-2 (Plek2), binds to Plek2-DEP domain with high affinity (Kd=160 nM).
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DC74102 | NSC33353 |
NSC33353 (NSC 33353) is a small molecule inhibitor with potent anti-tumor activity against TNBC cells, enhances TNBC sensitivity to doxorubicin.
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DC74101 | NSC 773097 |
NSC 773097 is a RITA analog that produces hyperselective cytotoxicity while maintaining antitumor efficacy (A498 cell IC50=130 nM).
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DC74100 | NPD389 |
NPD389 is a potent, selective, fast-binding uncompetitive inhibitor of NADP+-dependent malic enzyme 2 (ME2) with IC50 of 4.63 uM, NPD389 is a mixed-type competitive inhibitor for the substrate L-malate and an uncompetitive inhibitor for the other substrat
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DC74099 | NOX-6-7 |
NOX-6-7 is a potent, selective GPR132 agonist with EC50 of 44 nM.
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DC74096 | NIO-1 |
NIO-1 (Novel inhibitor of OCT1) is a novel small molecule inhibitor of Octamer transcription factor OCT1, inhibits OCT1 activation with IC50 of 0.11 uM.
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DC74094 | NERx 329 |
NERx 329 (RPAi 329, NERx329) is a novel potent, specific inhibitor of replication protein A (RPA), demonstrated potent RPA inhibitory activity in vitro, in vivo, and in cellular assays.
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DC74092 | NCI-41356 |
NCI-41356 is a small molecular inhibitor of αB-crystallin (CRYAB, HSPB5), significantly reducesthe interaction between CRYAB and VEGF165.
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DC74091 | NCGC00507974 |
NCGC00507974 is a small molecule inhibitor of Mir155 reporter, dose-dependently inhibits Mir155 reporter expression with EC50 of 1.2 uM.
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DC74089 | NCGC00108248 |
NCGC00108248 is small molecule inhibitor of Mir155 reporter, dose-dependently inhibits Mir155 reporter expression with EC50 of 2.2 uM.
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DC74088 | Nalacin |
Nalacina is a small molecule that partially mimicks the effects of auxin and potent inhibitor of indole-3-acetic acid (IAA) conjugation mediated by group II GH3 (Gretchen Hagen 3) in vascular plants, inhibits Gretchen Hagen 3 (GH3) acyl acid amido synthet
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DC74087 | MY-9B |
MY-9B is a selective, allosteric and covalent inhibitor of sterile alpha toll/interleukin receptor motif containing-1 (SARM1) with IC50 of 1.2 uM, site-specifically and stereoselectively modify cysteine-311 (C311) in the noncatalytic, autoregulatory armad
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DC74086 | msR4M-L1 |
msR4M-L1 is a chemokine-selective CXCR4 ectodomain mimic that selectively binds to MIF (KD<40 nM) but not CXCL12 (>140-fold selectivity).
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DC74085 | MS0621 |
MS0621 (UNC0621, MS 0621) is a small-molecule modulator of EWSR1::FLI1-mediated chromatin, reverses EWSR1::FLI1-mediated chromatin accessibility, persistently and selectively inhibits cell proliferation in Ewing sarcoma cell lines (SK-N-MC, IC50=128 nM).
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DC74084 | MrgX1 modulator 8e |
MrgX1 inhibitor 8e is a potent, allosteric modulator of MrgX1 with EC50 of 13 nM, showed improved potency and microsomal stability than ML382.
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DC74082 | MO-I-1100 |
MO-I-1100 is a small molecule inhibitor of aspartyl-(asparaginyl)-β-hydroxylase (ASPH), inhibits the β-hydroxylase activity of ASPH about 80%, inhibits Notch signaling in HCC cancer cells.
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DC74081 | MN256.0105 |
MN256.0105 is a small-molecule APOBEC3G DNA cytosine deaminase inhibitor with IC50 of 4.3 uM.
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DC74080 | MN256.0102 |
MN256.0102 is a small-molecule APOBEC3G DNA cytosine deaminase inhibitor with IC50 of 3.9 uM.
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DC74079 | MN132.0262 |
MN132.0262 is a small molecule, dual inhibitor of A3G (APOBEC3G, IC50=20 uM).
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DC74078 | MM0299 analog 13 |
MM0299 analog 13 (MM 0299 derivative 13) is a potent, selective, orally bioavailable, brain-penetrant inhibitor of lanosterol synthase (LSS, competition EC50=28.7 nM) with anti-proliferative activity.
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DC74077 | MM0299 |
MM0299 (MM 0299) is a potent, selective inhibitor of lanosterol synthase (LSS, competition EC50=1.97 nM) with anti-proliferative activity, inhibits Mut6 cell growth (IC50=18.2 nM) and induces the synthesis of 24(S),25-epoxycholesterol (EPC).
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DC74076 | MLS000544460 |
MLS000544460 (EYA2i) is a specific, allosteric inhibitor of Eya2 phosphatase with IC50 of 4.1 uM, KD of 2.0 uM, does not bind Eya3 ED, Eya1 and Eya4 ED.
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DC74075 | ML181 |
ML181 (CYM50557) is a potent and selective GPR7 (Neuropeptides B/W receptor 1, NPBW1) antagonist probe with IC50 of 270 nM for inhibition of NPW-induced GPR7 activation.
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DC74074 | Mito-LND |
Mito-LND (Mito-lonidamine) is a tumor-selective inhibitor of oxidative phosphorylation with IC50 of 1.2 and 2.4 uM for mitochondrial complexes I and II, respectively, impacts the activity of mitochondrial complexes, ROS generation and peroxiredoxin oxidat
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DC74073 | MitoCKi |
MitoCKi (Creatine kinase inhibitor CKi-26) is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 185 nM, depletes creatine phosphagen energetics in cells.
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