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Cat. No. Product Name Field of Application Chemical Structure
DC80149 AChE-IN-98
AChE-IN-98 (Compound 26) is an AChE inhitibor, with an IC50 value of 7.3 μM for ee AChE. AChE-IN-98 is also a Coumarin derivative. AChE-IN-98 can be used in the research of Alzheimer's disease.
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DC80146 AChE/MAO-B-IN-9
AChE/MAO-B-IN-9 (Compound E12) is an orally active, selective, reversible, non-competitive AChE and MAO-B inhibitor, with an IC50 of 0.156 μM against electric eel AChE. AChE/MAO-B-IN-9 inhibits Aβ40/42 fibril formation, promotes Aβ fibril depolymerization, and inhibits Tau protein fibril formation. AChE/MAO-B-IN-9 exerts antioxidant and neuroprotective effects, and improves scopolamine-induced memory impairment in mice. AChE/MAO-B-IN-9 can be used for the research of Alzheimer's disease.
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DC80141 ABC transporter modulator-3
ABCC6 modulator-3 (Compound I-71) is a ABCC6 activator with an EC50 < 1 μM. ABCC6 modulator-3 upregulates the expression of wild-type ABCC6. ABCC6 modulator-3 is used in research on diseases associated with ABC transporter dysfunction.
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DC80137 AAK1-IN-12
AAK1-IN-12 (Compound 4) is a selective, orally active AAK1 inhibitor that can cross the blood-brain barrier. AAK1-IN-12 is applicable to the research of schizophrenia, Parkinson's disease, neuropathic pain and Alzheimer's disease.
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DC80125 8-Aminoguanosine
8-Aminoguanosine is a purine nucleoside phosphorylase inhibitor. 8-Aminoguanosine blocks purine nucleoside phosphorylation via specific binding.
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DC80119 7.9 MAG
7.9 MAG is a non-monoolein lipid and acts as a detergent for crystallization.
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DC80118 6-Nitroquipazine
6-Nitroquipazine (DU24565) is a potent and selective 5-HT transporter inhibitor, with a Ki of 0.17 nM. 6-Nitroquipazine can be used in the research of psychiatric disorders such as depression.
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DC80115 6ECA
6ECA is a selective TGR5 receptor activator with an EC50 of 3.44 μM. 6ECA shows no significant activity at FXR. 6ECA can be used for the study of diabesity.
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DC80114 6-Amino-1-hexanethiol hydrochloride
6-Amino-1-hexanethiol hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
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DC80113 5β-Cholanic acid-3,6-dione
5β-Cholanic acid-3,6-dione (3,6-Diketo-LCA) is a similar substance to Lithocholic acid (LCA). 5β-Cholanic acid-3,6-dione cannot activate the Vitamin D receptor (VDR), and can be used as a negative control for studying the relationship between LCA derivatives and VDR.
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DC80110 5-HT7R antagonist 5
5-HT7R antagonist 5 (Compound (R)-4) is a 5-HT7AR antagonist, with a Ki of 46.4 nM. 5-HT7R antagonist 5 shows anticancer effects against prostate cancer.
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DC80104 5-HT2A&5-HT2C agonist-3
5-HT2A&5-HT2C agonist-3 (compound 4e) is an orally bioavailable and blood-brain barrier penetrant agonist of 5-HT2A and 5-HT2C. 5-HT2A&5-HT2C agonist-3 increases intracellular calcium levels in cells overexpressing 5-HT2A or 5-HT2C receptors, and shows no activity against 5-HT2B receptors. 5-HT2A&5-HT2C agonist-3 can be used for the research of neuropsychiatric disorders.
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DC80096 5-Amino-2'-deoxyuridine
5-Amino-2'-deoxyuridine is a thymidine analogue and substrate for chemical reaction. 5-Amino-2'-deoxyuridine can be use in the preparation of labeled probes for DNA microarray analysis.
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DC80078 4-Bromoisophthalic acid
4-Bromoisophthalic acid (4-Bromo-1,3-benzenedicarboxylic acid) is a metal-organic framework (MOF).
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DC80067 3'-O-(2-Nitrobenzyl)-dCTP
3'-O-(2-Nitrobenzyl)-dCTP is a reversible terminator. 3'-O-(2-Nitrobenzyl)-dCTP can be recognized and incorporated by polymerases, thereby temporarily terminating primer extension during DNA synthesis. After incorporation into the extending DNA strand, 3'-O-(2-Nitrobenzyl)-dCTP temporarily halts the DNA polymerase extension reaction, and its 3'-O-(2-nitrobenzyl) blocking group can be removed by laser irradiation to regenerate a free 3'-OH for subsequent primer extension cycles. 3'-O-(2-Nitrobenzyl)-dCTP is applicable for resolving homopolymeric regions in DNA templates.
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DC80057 3-Benzylmalic acid
3-Benzylmalic acid (3-Benzylmalate) can be converted from 2-Benzylmalic acid through a HphCD-mediated hydroxyl isomerization reaction.
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DC80053 3-[4-(2-Propyn-1-yloxy)phenyl]-2H-azirine
3-[4-(2-Propyn-1-yloxy)phenyl]-2H-azirine (Compound AZ-9) is a reactive probe based on 3-phenyl-2H-azirine, enabling chemoselective bioconjugation of carboxyl residues in proteins with excellent labeling efficiency and specificity under both in vitro and in situ conditions in live cells.
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DC80046 2-Oxo-(4R)-hydroxy-5-aminovaleric acid
2-Oxo-(4R)-hydroxy-5-aminovaleric acid is a nucleoside metabolite.
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DC80045 2'-Nitroflavone
2'-Nitroflavone is a PARP1 inhibitor. 2'-Nitroflavone inhibits the proliferation, induces cell cycle arrest and apoptosis of triple-negative breast cancer cells. 2'-Nitroflavone also inhibits the migration of triple-negative breast cancer cells and endothelial cells. 2'-Nitroflavone exhibits antitumor activity and can be used in the research of tumors such as triple-negative breast cancer.
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DC80043 2-MSP(4-OMe)-5-HA-PEG8-VA-Exatecan
2-MSP(4-OMe)-5-HA-PEG8-VA-Exatecan is a Drug-linker conjugates for ADC consisting of the ADC Cytotoxin Exatecan and a linker. 2-MSP(4-OMe)-5-HA-PEG8-VA-Exatecan can be used for synthesis of ADCs.
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DC80031 23(Z),26(Z),29(Z),32(Z),35(Z)-Octatriacontapentaenoic acid
23(Z),26(Z),29(Z),32(Z),35(Z)-Octatriacontapentaenoic acid is a fatty acid.
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DC80029 20-HETE IN-3
20-HETE IN-3 is an orally bioavailable 20-HETE synthesis inhibitor. 20-HETE IN-3 can be used in the research of obesity.
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DC80028 20b-Dihydroprogesterone
20b-Dihydroprogesterone (Compond III) is a C-21 steroid found in water beetles Cybister limbatus, C. tripunctatus and C. confuses.
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DC80027 20(Z),23(Z),26(Z),29(Z),32(Z),35(Z)-Octatriacontahexaenoic acid
20(Z),23(Z),26(Z),29(Z),32(Z),35(Z)-Octatriacontahexaenoic acid is an unsaturated fatty acid.
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DC80024 2,3-Dimethylbenzoic acid
2,3-Dimethylbenzoic acid is a transition metal catalyst.
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DC80022 2-(Dimethylamino)ethylphosphonic acid
2-(Dimethylamino)ethylphosphonic acid is a nucleoside metabolite.
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DC80019 2-(2-Chloroethoxy)ethanol
2-(2-Chloroethoxy)ethanol is an unclassified residual solvent and known impurity, with an acceptance criterion of 0.10%.2-(2-Chloroethoxy)ethanol serves as a starting material in quetiapine synthesis.
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DC80016 1-Stearin-2-petroselinin-3-olein
1-Stearin-2-petroselinin-3-olein is an acylglycerol.
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DC80014 1-Palmitin-2-sapienoin-3-palmitolein
1-Palmitin-2-sapienoin-3-palmitolein is an acylglycerol.
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DC80009 1-Myristoyl-2-oleoyl-3-docosanoyl-rac-glycerol
1-Myristoyl-2-oleoyl-3-docosanoyl-rac-glycerol is an acylglycerol.
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