LBL1 |CAS 1605301-58-3|DC Chemicals

Cas No.:	1605301-58-3
Chemical Name:	N-(1-amino-7H-pyrrolo[3,2-f]quinazolin-3-yl)-2-naphthamide
Synonyms:	Lamin A inhibitor LBL1
Formula:	C₂₁H₁₅N₅O
M.Wt:	353.385
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

LBL1 (Lamin A inhibitor LBL1) is a novel pyrroloquinazoline compound with significant anticancer activity, targets nuclear lamins and binds to the coiled-coil domain of lamin A (Kd=5.11 uM); demonstrates growth inhibitory activities against MDA-MB-468 and MDA-MB-231 breast cancer cell lines with GI50 of 0.44 and 1.60 uM, respectively; binds to LA(1-387) both in vitro and in living cells.

MSDS

COA

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2018-0101

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