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Cat. No. Product Name Field of Application Chemical Structure
DC38044 Nadoxolol hydrochloride
Nadoxolol HCl is a beta-adrenergic receptor blocker.
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DC35055 Biotin-PEG3-amine
Biotin-PEG3-amineis PEG derivative containing a biotin group and a terminal primary amine group. The amine group can be coupled to carboxyl groups or 5'phosphate groups to form stable amide bonds. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC36187 Alprostadil ethyl ester
Alprostadil ethyl ester is a biochemical used in the treatment of scleroderma.
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DC34108 Novokinin
Novokinin is an angiotensin AT2 receptor agonist. Novokinin exhibits vasorelaxing and hypotensive activity via activation of the IP (prostacyclin) receptor, and suppresses food intake via activation of PGE2-EP4 interaction.
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DC36277 GKK1032B
GKK1032B is a fungal metabolite that has antiproliferative and antibacterial activities. GKK1032B inhibits the growth of HeLa S3 cervical and MCF-7 breast cancer cells and Vero cells. It also inhibits the growth of B. subtilis and M. tuberculosis.
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DC31606 Cefaloglycin
Cefaloglycin is a first-generation semisynthetic cephalosporin with antibacterial activity. Cephaloglycin binds to and inactivates penicillin-binding proteins located on the inner membrane of the bacterial cell wall. This results in the weakening of the bacterial cell wall and causes cell lysis.
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DC36776 Cynaropicrin
Cynaropicrin is the first plant natural product with in vivo activity against Trypanosoma brucei.
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DC33426 4-(p-Acetoxyphenyl)-2-butanone
Cuelure is a hormonal attractant for male Bactrocera flies.
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DC34642 Valerenic acid
Valerenic acid is a ?-subunit-dependent GABAA receptor modulator.
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DC37021 Ponceau 3R
Ponceau 3R (C.I. 16155) is an azo dye that once was used as a red food colorant.
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DC34078 Ani9
Ani9 is a potent ANO1 inhibitor. Anoctamin1 (ANO1)/transmembrane protein 16A (TMEM16A), a calcium-activated chloride channel (CaCC), is involved in many physiological functions such as fluid secretion, smooth muscle contraction, nociception and cancer progression. Ani9 may be a useful pharmacological tool for studying ANO1 and a potential development candidate for drug therapy of cancer, hypertension, pain, diarrhea and asthma.
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DC35566 m-PEG3-aldehyde
m-PEG3-aldehyde is a PEG derivative containing an aldehyde group. Aldehyde is reactive to hydrazide and aminooxy groups which are commonly used in biomolecular probes for labeling and crosslinking carbonyls (oxidized carbohydrates). The hydrophilic PEG spacer increases solubility in aqueous media.
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DC36624 Cyclohexene
Cyclohexene, decafluoro- is also known as Perfluorocyclohexene. Perfluorocycloalkene (PFCA) is a general class of fluorocarbon compounds comprising many commercially available perfluorocyclo-olefins including hexafluorocyclobutene (or perfluorocyclobutene), octafluorocyclopentene (or perfluorocyclopentene ) and decafluorocyclohexene (or perfluorocyclohexene ). Perfluorocycloalkene is a cycloalkene with no aromatic character, and has only carbon and fluorine, but no hydrogen.
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DC37026 Perflexane
Perflexane was developed as an ultrasound (US) contrast agent for use in echocardiograms to enhance US images.
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DC34191 4-CPI
4-CPI is an inhibitor of non-active site mutants of cytochrome P450 2B4.
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DC36519 Acid blue 3
Acid blue is also known as Patent Blue V, and is a dark bluish synthetic triphenylmethane dye used as a food coloring. As a food additive, it has E number E131. It is a sodium or calcium salt of [4-(α-(4-diethylaminophenyl)-5-hydroxy- 2,4-disulfophenylmethylidene)-2,5-cyclohexadien-1-ylidene] diethylammonium hydroxide inner salt. The color of the dye is pH-dependent. In aqueous solution, its color will vary from a deep blue in alkaline or weakly acidic medium to a yellow–orange in stronger acidic conditions. It is useful as a pH indicator for the range 0.8–3.0. The structure is also redox-sensitive, changing from a reduced yellow form to an oxidized red form in solution. The reduction potential of around 0.77 volts is similar to that of other triphenylmethane dyes. It is usable as a reversible redox indicator in some analytical methods.
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DC34381 Phox-I2
Phox-I2 is a second generation inhibitor of the p67phox interaction with Rac1, effective in suppressing reactive oxygen species production by human and murine neutrophils.
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DC36710 Dechloro perphenazine
Dechloro perphenazine is the dechlorinated analogue of Perphenazine (P291100), an D2 dopamine receptor antagonist; α-adrenergic receptor antagonist and σ-receptor agonist.
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DC37348 Glycocyamine
Glycocyamine is an indicator and Reagent.
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DC37207 Methyl benzoin
Methyl benzoin is a biochemical.
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DC35450 Azide-PEG8-alcohol
Azide-PEG8-alcohol is a PEG derivative containing an azide group and a terminal hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
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DC35254 Azidoethyl-SS-ethylazide
Azidoethyl-SS-ethylazide is a cleavable PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC37961 Erythromycin estolate
Erythromycin estolate is a macrolide antibiotic, produced by Streptomyces erythreus. It is the lauryl sulfate salt of the propionic ester of erythromycin. This erythromycin salt acts primarily as a bacteriostatic agent. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
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DC37380 Setoglaucine
Setoglaucine is a basic dye used to stain DNA.
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DC38026 Benzidine orange
Benzidine orange exhibits mutagenic and carcinogenic activity.
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DC37681 L 12407
L 12407 is an antiprotozoal drug of the nitroimidazole class used in veterinary medicine. It is used for the treatment of histomoniasis in turkeys and for swine dysentery.
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DC34426 2002-H20
2002-H20 is an inhibitior of Aβ42-induced cytotoxicity. It acts by binding the Alzheimer's Aβ peptide and reducing its cytotoxicity.
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DC36892 DPTIP
DPTIP is a potent and selective N-SMase2 inhibitor and brain penetrant.
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DC34055 L-703606 Oxalate
L-703606 Oxalate is a tachykinin NK1 receptor antagonist.
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DC35492 PEG21
PEG21 is a PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.
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