PEG18 is a PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.

Necrostatin-7 is a necroptosis inhibitor. It acts by inhibiting TNF-alpha-induced necroptosis in a FADD-deficient variant of human Jurkat T cells.

NHS-Biotin, Succinimidobiotin, is a primary amine reactive biotinylation reagent used in Biotin-Streptavidin binding reactions. The NHS-Biotin molecule is cell membrane permeable and can be used to covalently label intracellular proteins.

Sulbentine (or dibenzthione) is an antifungal chemical.

Pyrene is one of the simplest polyaromatic hydrocarbons (PAHs). Pyrene derivatives are known for their ability to intercalate dsDNA. Pyrene possesses intrinsic fluorescence. When two pyrene residues are located in close proximity, excimer formation can be observed by fluorescence spectroscopy. Pyrene has been therefore used to probe structures of biomolecules. Ethynylpyrene molecule contains terminal triple bond fragment for Click Chemistry, as well as other coupling reactions such as Sonogashira coupling.

JX-401 is a p38alpha inhibitor containing a 4-benzylpiperidine motif. p38alpha is hyperactive in inflammatory diseases, and various indications suggest that its inhibition would reverse inflammation.

Trimethylcolchicinic acid is an antimitotic agent disrupting microtubule action through the binding of tubulin and preventing polymerization. Has been shown to stimulate the intrinsic GTPase activity of tubulin. Induces apoptosis and activates the JNK/SAPK signals.

Diethylcarbamazine N-Oxide is a metabolite of Diethylcarbamazine (D443910) in mammals. Diethylcarbamazine N-Oxide shows more antifilarial activity than its parent compound.

Trimethylcolchicinic acid methyl ether, Antimitotic agent that intercepts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signal.

ITX3 is a nontoxic selective cell active inhibitor of the Trio/RhoG?/Rac1 pathway. It acts by validating RhoGEFs as druggable targets.

Phenyl nicotinate is a biochemical.

Phthalogen, also known as 1H-Isoindol-3-amine, 1-imino- is a dye used in developing photoreceptor-based models of visual attraction in riverine tsetse, for use in the engineering of more-attractive polyester fabrics for control devices.

Butocarboxime is used as an acaricide and insecticide.

Dihydrotetrabenazine (racemic) is an active metabolite of the vesicular monoamine transporter 2 (VMAT2) inhibitor tetrabenazine that is generated by hepatic carbonyl reductases. Dihydrotetrabenazine binds to mouse pons medulla, hypothalamus, and striatum and inhibits synaptic vesicular serotonin (5-HT) uptake. It also binds to human caudate nucleus, hippocampus, and substantia nigra pars compacta. Dihydrotetrabenazine stereoisomers bind to VMAT2 in rat striatum.

5-Methylurapidil is an alpha1A-adrenoceptor antagonist. It has also been used for competitive binding in radioligand binding assays.

Ms-PEG3-Ms is a PEG Linker.

4-Nitrobenzanilide is a biochemical.

Amidinomalonamide hydrochloride is a chemical reagent used in the preparation of pyrimidooxazines used as DGAT1 inhibitors. This drug has potential use as an anti-obesity treatment.

Boromycin is a boron-containing macrolide antibiotic that inhibits growth of B. subtilis and induces efflux of potassium ions from B. subtilis without affecting Na+/K±ATPase activity. It decreases the synthesis of protein, RNA, and DNA in B. subtilis, inhibits the growth of B. halodurans, and inhibits the futalosine pathway of menaquinone synthesis in B. halodurans. Boromycin reverses bleomycin-induced cell cycle arrest at the G2 phase in Jurkat cells. It inhibits replication of the HIV-1 strains LAV-1 and RF and the HIV-2 strain LAV-2 in MT-4 cells. It also inhibits replication of a clinical isolate of HIV-1, strain KK-1, in MT-4 cells and peripheral blood mononuclear cells.

Alkynyl Stearic Acid can be used to identify and characterize the post-translational acylation of proteins with powerful Click Chemistry.

Arginylphenylalaninamide is a fragment of FMRamide; may be used as a neurotransmitter or neuromodulator by optic lobe neurons of different types.

Kynurenine is a metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway. It causes vasodilation and hypotension induced by activation of KCNQ-encoded voltage-dependent K(+) channels..

L48H37 is a specific myeloid differentiation 2 (MD2) inhibitor.

Mal-PEG2-alcohol is a PEG derivative containing a maleimide group and a hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

SDM-25N HCl is a selective δ-opioid receptor antagonist.

Lidoflazine is a piperazine calcium channel blocker. It is a coronary vasodilator with some antiarrhythmic action.

Vigilor, also known as Fipexide hydrochloride, is a biochemical which may act as a cognition activator.

Trimebutine Maleate is a drug with antimuscarinic and weak mu opioid agonist effects. Trimebutine Maleate modulates the calcium and potassium channels, relieves abdominal pain in patients with irritable bowel syndrome. Trimebutine Maleate is used for treatment of irritable bowel syndrome and other gastrointestinal disorders.

6-Isopropyl-2-decalone is used in the synthesis of 6-Isopropyl-2-decahydronaphthalenol,which is a fragrance raw material, used in the perfumery industry.

T-2 Mycotoxin is a trichothecene mycotoxin. It is a naturally occurring mold byproduct of Fusarium spp. fungus which is toxic to humans and animals.