Cat. No. | Product Name | Field of Application | Chemical Structure |
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DC36146 | AI3-63042 |
Gallein is a Gβγ subunit signalling inhibitor which has been shown to inhibit metastatic spread of tumour cells expressing OR51E2 and exposed to its odorant ligand.
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DC37526 | Amarogentin |
Amarogentin displays immunomodulatory effects in human Mast Cells and Keratinocytes.
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DC34868 | N-Boc-N-bis(PEG2-propargyl) |
N-Boc-N-bis(PEG2-propargyl) is a branched PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC35507 | N-(PEG1-OH)-N-Boc-PEG2-propargyl |
N-(PEG1-OH)-N-Boc-PEG2-propargyl is a branched PEG derivative with a terminal hydroxy group, propargyl group, and a Boc protected amino group. The hydroxy group enables further derivatization or replacement with other reactive functional groups. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The protected amine can be deprotected by acidic conditions.
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DC34867 | NH-bis(PEG2-propargyl) |
NH-bis(PEG2-propargyl) is a branched PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34984 | Aminooxy-PEG4-t-butyl ester |
Aminooxy-PEG4-t-butyl ester is a PEG derivative containing an aminooxy group and a t-butyl ester group. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
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DC35762 | NH-bis(PEG1-azide) |
NH-bis(PEG1-azide) is a PEG derivative containing an amino group with two azide groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls. The azide groups enable PEGylation via Click Chemistry.
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DC35499 | Hydroxy-PEG5-methyl ester |
Hydroxy-PEG5-methyl ester is a PEG derivative containing a hydroxyl group and a methyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Methyl ester can be hydrolyzed under strong basic condition.
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DC35781 | N-Boc-N-bis(PEG1-azide) |
N-Boc-N-bis(PEG1-azide) is a branched PEG derivative with two terminal azide groups and a Boc protected amino group. The azide groups enable PEGylation via Click Chemistry. The protected amine can be deprotected by acidic conditions.
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DC34862 | Hydroxy-Amino-bis(PEG2-propargyl) |
Hydroxy-Amino-bis(PEG2-propargyl) is a symmetrical branched alkyne PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC35121 | N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester |
N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester is a Biotin PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC35118 | N-(Biotin)-N-bis(PEG1-alcohol) |
N-(Biotin)-N-bis(PEG1-alcohol) is a PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC35029 | Benzyloxy carbonyl-PEG3-acid |
Benzyloxy carbonyl-PEG3-acid is a Benzyl PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC35208 | Bromo-PEG3-CH2CO2tBu |
Bromo-PEG3-CH2CO2tBu is a PEG derivative containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
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DC34975 | Aminooxy-PEG1-azide |
Aminooxy-PEG1-azide is a PEG derivative containing an aminooxy group and an azide group. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
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DC34872 | N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl) |
N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl) is a branched alkyne PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC35030 | Benzyloxy carbonyl-PEG3-NHS ester |
Benzyloxy carbonyl-PEG3-NHS ester is a Benzyl PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC35005 | t-Boc-Aminooxy-PEG1-azide |
t-Boc-Aminooxy-PEG1-azide is a crosslinker containing a t-Boc-aminooxy group and an azide group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Aminooxy PEG Linkers may be useful in bioconjugation experiments.
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DC35008 | t-Boc-Aminooxy-PEG4-azide |
t-Boc-Aminooxy-PEG4-azide is a crosslinker containing a t-Boc-aminooxy group and an azide group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Aminooxy PEG Linkers may be useful in bioconjugation experiments.
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DC34869 | N-(Boc-PEG1)-N-bis(PEG2-propargyl) |
N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a branched alkyne PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34864 | N-(Propargyl-PEG2)-N-bis(PEG1-alcohol) |
N-(Propargyl-PEG2)-N-bis(PEG1-alcohol) is a branched alkyne PEG Linker. The alcohol groups can be replaced with other groups via addition reactions. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34976 | Aminooxy-PEG4-azide |
Aminooxy-PEG4-azide is a PEG derivative containing an aminooxy group and an azide group. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
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DC34928 | Amino-PEG2-t-Boc-hydrazide |
Amino-PEG2-t-Boc-hydrazide is a PEG derivative containing an amino group and a Boc-protected hydrazide. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc can be deprotected under mild acidic conditions to form a reactive hydrazide, which can then be coupled with various carbonyl groups. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC35175 | Azido-PEG2-t-Boc-hydrazide |
Azido-PEG2-t-Boc-hydrazide is a PEG derivative containing an azide group and a Boc-protected hydrazide. The azide group can react with alkyne groups, BCN, and DBCO via Click Chemistry to yield a stable triazole linkage. The Boc can be deprotected under mild acidic conditions to form a reactive hydrazide, which can then be coupled with various carbonyl groups.
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DC34796 | Alkyne-ethyl-PEG1-t-Butyl ester |
Alkyne-ethyl-PEG1-t-Butyl ester is a PEG derivative containing an alkyne group and a t-butyl protected carboxyl group. The alkyne can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.
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DC35676 | Ald-CH2-PEG4-CH2CO2tBu |
Ald-CH2-PEG4-CH2CO2tBu is a PEG Linker.
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DC35861 | N-Mal-N-bis(PEG4-acid) |
N-Mal-N-bis(PEG4-acid) is a branched PEG derivative with two terminal carboxylic acids and a maleimide group. The terminal carboxylic acids can be reacted with primary amino groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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DC35867 | N-Mal-N-bis(PEG2-t-butyl ester) |
N-Mal-N-bis(PEG2-t-butyl ester) is a branched PEG derivative with a terminal maleimide group and two terminal t-butyl esters. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The t-butyl protected carboxyl groups can be deprotected under mild acidic conditions.
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DC35795 | N-(Azido-PEG3)-N-Fluorescein-PEG3-acid |
N-(Azido-PEG3)-N-Fluorescein-PEG3-acid is a fluroescent PEG Linker.
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DC34863 | N-(Acid-PEG2)-N-bis(PEG2-propargyl) |
N-(Acid-PEG2)-N-bis(PEG2-propargyl) is a branched alkyne PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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