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Cat. No. Product Name Field of Application Chemical Structure
DC35920 Propargyl-PEG3-phosphonic acid
Propargyl-PEG3-phosphonic acid is a crosslinker containing a propargyl group and a phosphonic acid. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC34665 Monensin
Monensin is an antiprotozoal agent produced by Streptomyces cinnamonensis. Monensin is a sodium and proton selective ionophore and is widely used as such in biochemical studies, particularly as an anti-tumor agent. It has an inhibitory effect on the Wnt/β-catenin signaling cascade, which may be useful when the cascade is aberrantly activated in cancer cells. Monensin is a prospective anticancer drug for therapy of neoplasia with deregulated Wnt signaling.
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DC36103 Doxycycline monohydrate
Doxycycline monohydrate is a synthetic tetracycline derivative with similar antimicrobial activity.
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DC36920 Sonepiprazole
Sonepiprazole is a a selective dopamine D4 antagonist.
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DC38061 Isoloratadine
Isoloratadine is a Loratadine impurity. An isomer of Loratadine used for preparation of tricyclic amides and ureas useful for inhibition of G-protein function and for treatment of proliferative diseases.
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DC36169 AL-6598
AL-6598 is a DP prostaglandin receptor agonist which may lead to sustained intraocular pressure reduction. This bioactivity may be useful in the treatment of glaucoma.
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DC33751 1-(4-Pyridinyl)-1-propanone
1-(4-Pyridinyl)-1-propanone is chemical for drug synthesis
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DC37956 Laudanosine
Laudanosine is a recognized metabolite of atracurium and cisatracurium. Laudanosine decreases the seizure threshold, and thus it can induce seizures if present at sufficient threshold concentrations; however such concentrations are unlikely to be produced consequent to chemodegradable metabolism of clinically administered doses of cisatracurium or atracurium.
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DC37583 Dipyridamole tripiperidine
Dipyridamole tripiperidine is a biochemical.
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DC35233 Bromoacetamido-PEG8-acid
Bromoacetamido-PEG8-acid is a PEG derivative containing a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
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DC35944 Tos-PEG5-CH2CO2tBu
Tos-PEG5-CH2CO2tBu is a PEG derivative containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.
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DC35430 Hydroxy-PEG4-CH2CO2tBu
Hydroxy-PEG4-CH2CO2tBu is a PEG derivative containing a hydroxyl group with a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
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DC34740 Sulfo-LC-SPDP Crosslinker
Sulfo-LC-SPDP Crosslinker, or Sulfosuccinimidyl 6-(3'-[2-pyridyldithio]-propionamido)hexanoate, is a cleavable, water soluble, amino and thiol (sulfhydryl) reactive heterobifunctional protein crosslinker. The "long chain" Sulfo-LC-SPDP crosslinking reagent has a 15.7 angstrom spacer arm, and is the water soluble analog of LC-SPDP crosslinker.
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DC34780 Propargyl-PEG4-CH2CO2H
Propargyl-PEG4-CH2CO2H is a PEG derivative containing a propargyl group with a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.
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DC37020 Acid Violet 6B
Acid Violet 6B is a dye.
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DC37653 Ioxynil
Ioxynil is a herbicide. Ioxynil is a plant protection active substance and a chemical compound from the group of substituted phenols, nitriles and organic iodine compounds .
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DC35737 Azide-PEG4-Tos
Azide-PEG4-Tos is a PEG derivative containing an azide group and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The tosyl group is a good leaving group for nucleophilic substitution reactions.
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DC36936 Hydroaminacrine
Tacrine hydrochloride is a cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
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DC36880 Noratropine
Noratropine is a metabolite of Atropine (A794625).
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DC37315 Nicotinic anhydride
Nicotinic anhydride is a biochemical.
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DC35989 Tetrazine-PEG5-NHS ester
Tetrazine-PEG5-NHS ester is a PEG derivative containing a tetrazine group and an NHS ester. The hydrophilic PEG spacer increases water-solubility. It is one of the most reactive tetrazines commercially available. Hydrogen substituted tetrazines demonstrate exceptionally fast kinetics compared to methyl substituted tetrazines.
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DC37969 Pantethine
Pantethine is a derivative of vitamin B5.
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DC35517 N-Benzyl-N-bis(PEG3-OH)
N-Benzyl-N-bis(PEG3-OH) is a PEG Linker
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DC34241 TASIN-1 Hydrochloride
TASIN-1 Hydrochloride is a truncated APC selective inhibitor. It acts by selectively killing colorectal cancer cells that express truncated APC by reducing cellular cholesterol levels and inducing apoptotic cell death through the ER stress/ROS/JNK signaling in colon cancer cells.
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DC36257 Z-LRGG-AMC (trifluoroacetate salt)
Z-LRGG-AMC TFA is a fluorogenic substrate for isopeptidase T. Upon enzymatic cleavage by isopeptidase T, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify isopeptidase T activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
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DC37943 Methomyl
Methomyl is a carbamate insecticide with anticholinesterase activity.
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DC36009 Lipoamido-PEG2-alcohol
Lipoamido-PEG2-alcohol is a PEG Linker.
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DC33755 Octanophenone
Octanophenone can be analyzed by this reverse phase (RP) HPLC method with simple conditions. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 μm particles columns available for fast UPLC applications. This method is scalable and can be used for isolation impurities in preparative separation.
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DC34538 TerpendoleE
Terpendole E is an atypical L5 site inhibitor.
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DC34753 Sulfo-EGS Crosslinker
Sulfo-EGS Crosslinker, or Ethylene glycol bis(sulfosuccinimidylsuccinate), is a water soluble homobifunctional crosslinker. Sulfo-EGS Crosslinker can be used to label cell surface proteins as the molecule is not cell membrane permeable.
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