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Cat. No. Product Name Field of Application Chemical Structure
DC32439 Anaprel
Rescinnamine is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug. It is a vinca alkaloid obtained from Rauwolfia serpentina and other species of Rauwolfia.
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DC32438 Tyrphostin AG 825
Tyrphostin AG 825 is shown to be a potent inhibitor of EGFR (epidermal growth factor receptor) and Neu (HER-2) kinases.
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DC32437 Tyrphostin AG 1112
Tyrphostin AG 1112 is a Bcr-Abl kinase blocker that can activate the terminal differentiation of K562 cells and the purging of Ph+ cells.
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DC32436 Tyrphostin 51
Tyrphostin 51 is a potent inhibitor of EGFR (EGF receptor) kinase activity
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DC32435 SKI 5C
SKI 5C is a selective Sphingosine Kinase 1 (SPHK1) inhibitor.
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DC32434 Roslin 2
Roslin 2 is a p53 reactivator that disrupts the FAK and p53 interaction, and reactivates transcriptional activity of p53 with p21, Mdm-2 and Bax transcriptional targets. Roslin 2 decreases viability and clonogenicity of cancer cells, and inhibits tumor growth.
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DC32433 PF-06439015
PF-06439015 is a potent and selective inihibitor that overcomes clinical ALK (receptor tyrosine kinase anaplastic lymphoma kinase) mutations resistant to Crizotinib.
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DC32432 PF-06250112
PF-06250112 is a potent inhibitor of Bruton′s tyrosine kinase
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DC32431 PD173952
PD173952 is a Src family kinase inhibitor.
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DC32430 NP603
NP603 is a cell-permeable inhibitor of PDGFRβ, FGFR1 and VEGFR2 that binds to ATP pocket. NP603 is a very weak inhibitor of EGFR
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DC32429 GW2974
GW2974 Potent and selective dual inhibitor of EGFR.
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DC32428 DMH4
DMH4 is a potent VEGF inhibitor and an angiogenesis inhbitor.
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DC32426 Calcon
Calcon is a biochemical indicator of calcium.
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DC32425 Alizarine Yellow R
Alizarine Yellow R is a yellow colored azo dye made by the diazo coupling reaction.
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DC32424 Oxazole yellow
Oxazole yellow is a fluorescent cyanine dye that binds to DNA and is used to detect apoptotic cells. Oxazole yellow does not enter live cells. However, during apoptosis the cytoplasmic membrane becomes slightly permeable, allowing entry of the dye. Oxazole yellow is often used along with propidium iodide (catalog no. P4170), a DNA dead cell stain that does not enter either live or apoptotic cells. The λEx/λEm of Oxazole yellow is 491/509.
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DC32423 Midecamycin
Midecamycin is a naturally occurring 16-membered macrolide that fits under the category of acetoxy-substituted macrolide antibiotics. In this molecule, an acetoxy group is substituted on the position 9 of the 16-member ring and on position 4 of the terminal sugar.
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DC32422 Josamycin
Josamycin is a macrolide antibiotic.
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DC32421 L 709049
L 709049 is a biochemical.
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DC32420 Yau 17
Yau 17 is a biochemical.
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DC32419 Yatein
Yatein is a natural product isolated from from Cleistanthus boivinianu or Chamaecyparis obtusa. Yatein suppresses herpes simplex virus type 1 replication in HeLa cells by interruption the immediate-early gene expression. The mechanisms of antiviral action of yatein seem to be mediated, by inhibiting HSV-1 α gene expression, including expression of the ICP0 and ICP4 genes, and by arresting HSV-1 DNA synthesis and structural protein expression in HeLa cells. Yatein showed antiproliferative activity against the HCT-116 human colon carcinoma cell line, with an IC50 > 10 uM.
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DC32418 Molinate
Molinate is a biochemical.
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DC32417 Carbofuran
Carbofuran is one of the most toxic carbamate pesticides.
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DC32416 Yakkasterone
Yakkasterone is a major metabolite of cholesterol formed during exposure of lung epithelial cells to ozone.
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DC32415 Niraxostat
Niraxostat is a biochemical.
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DC32414 Y 27152
Y 27152 is a biochemical.
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DC32412 Propham
Propham is a biochemical.
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DC32411 N-Benzyloxycarbonylglycine
N-Benzyloxycarbonylglycine
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DC32410 Polaprezinc
Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-oxidant, anti-ulcer and anti-inflammatory activities. Upon administration, polaprezinc increases the expression of various anti-oxidant enzymes, such as superoxide dismutase 1 (SOD-1), SOD-2, heme oxygenase-1 (HO-1), glutathione S-transferase (GST), glutathione peroxidase (GSH-px), peroxidredoxin-1 (PRDX1; PRXI) and PRXD5 (PRXV) in the gastric mucosa, which protect cells against reactive oxygen species (ROS).
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DC32409 Ziram
Ziram, also known as Zinc dimethyldithiocarbamate, is a coordination complex of zinc with dimethyldithiocarbamate. It is a pale yellow solid that is used as a fungicide, the vulcanization of rubber, and other industrial applications.
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DC32406 Caerulein
Caerulein is a specific decapeptide obtained from the skin of Hila caerulea, an Australian amphibian. Caerulein is similar in action and composition to CHOLECYSTOKININ. It stimulates gastric, biliary, and pancreatic secretion; and certain smooth muscle. It is used in paralytic ileus and as diagnostic aid in pancreatic malfunction.
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