Novel Zika virus (ZIKV) NS2B-NS3pro protease inhibitor

Novel Potent Inhibitor of the HIV-1 Nucleocapsid Protein

Novel Inhibitor for RNA-Dependent RNA Polymerase of Norovirus

Novel TRPV1 modulator, also modulating both CB1 and CB2 receptors

Selective and potent potentiator of nAChRs containing an α4

Novel allosteric modulator of the β2 adrenergic receptor (β2AR), binding to a pocket formed primarily by the cytoplasmic ends of transmembrane segments 1, 2, 6 and 7 as well as intracellular loop 1 and helix 8

Inhibitor of DprE1, an epimerase required for cell wall biosynthesis

Potent dual 5-lipoxygenase (5-LOX) inhibitor and platelet-activating factor (PAF) receptor antagonist

Novel SARS-CoV Mpro inhibitor which has its P1-phenylalanine residue bound to the relatively hydrophilic S1 pocket of the enzyme and yet exhibits a high inhibitory activity against SARS-CoV Mpro, with Ki = 2.24 ± 0.58 μM

Novel peptide STAT5 inhibitor, blocking IL-2/sIL-2Rα signaling and inhibiting T reg cell development

Novel ultrapotent and selective inhibitor of of human β-Factor XIIa

Novel Potent and Specific Target Of Rapamycin Complex 2 (TORC2) Inhibitor

Novel Hedgehog pathway inhibitor, revealing the receptor GPR39

Novel inhibitor of

Novel Epigenetic Inhibitor Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with In Vivo Efficacy in Multiple Myeloma

First-in-class dual PDE5 and HDAC6-selective inhibitor

Novel Matrix Metalloproteinase Inhibitor As a Potent Antihemorrhagic Agent

Novel selective agonist of cannabinoid CB2 receptors

Novel potent and selective dual inhibitor of c-Met and ALK, potently abrogating hepatocyte growth factor (HGF)-induced c-Met phosphorylation and cell migration, phosphorylation of ALK, EML4-ALK, and ALK resistance mutants in transfected cells

Novel inhibitor of

Novel chromophore-linked metallo-β-lactamase (MBL) substrate as potential inhibitor against a panel of clinically relevant MBLs

Precursor for tumor selective PET imaging (124I-CLR1404) or therapeutic radiation (131I-CLR1404)

Full agonist of GABAA receptors, acting as anxiolytic, sedative, hypnotic, amnesic, anticonvulsant and muscle relaxant agent

Long-acting benzodiazepine, producing the active metabolite desmethyl-diazepam, which is a partial agonist of the GABAA receptor

Herbicide safener that is added to various herbicide formulations to reduce crop damage

Hypolipaemic agent, reducing hypertriglyceridemia and hypercholesterolemia

Corticosteroid Hormone Receptor Agonist

Novel inhibitor of the human enzyme dimethylarginine dimethylaminohydrolase-1 (DDAH-1)

Potent and selective CLK1 and CLK2 inhibitor

Potent CLK1 and CLK2 inhibitor, also inhibiting SRPK1 and SRPK2